公开(公告)号：US20180238910A1

公开(公告)日：2018-08-23

申请号：US15878351

申请日：2018-01-23

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Ji Yoon KANG ,  Kyeong-Sik SHIN ,  Jae-hoon JI ,  Youhee HEO ,  Kyoseon HWANG ,  Myung-Sic CHAE

IPC: G01N33/68 ,  C12Q1/6883

CPC classification number: G01N33/6896 ,  A61B5/14507 ,  A61B5/14546 ,  A61B5/1468 ,  A61B5/1486 ,  A61B5/4088 ,  C12Q1/6883 ,  C12Q2600/158 ,  G01N2333/4709 ,  G01N2800/2821 ,  G01N2800/52

Abstract: A method for providing information relevant to the diagnosis of a neurodegenerative disorder. The method includes (i) obtaining a biological sample containing vesicles from a subject, (ii) measuring the level of amyloid beta in the biological sample using an antibody specific for the N-terminus of amyloid beta, and (iii) comparing the measured level of amyloid beta in the biological sample with the level of amyloid beta in a previously prepared control sample.