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公开(公告)号：US12064237B2
公开(公告)日：2024-08-20
申请号：US16980196
申请日：2019-03-12
申请人： Menicon Co., Ltd.
IPC分类号： A61B5/145 , A45C11/00 , A45C15/00 , A61B3/10 , A61B3/16 , A61B5/00 , A61B10/00 , G01N33/543 , G06N20/00 , G16H10/40 , G16H50/30
CPC分类号： A61B5/14532 , A45C11/005 , A45C15/00 , A61B3/101 , A61B3/16 , A61B5/0004 , A61B5/14507 , A61B5/14546 , A61B5/411 , A61B5/412 , A61B5/4824 , A61B5/6821 , A61B5/6847 , A61B5/7275 , A61B10/0045 , G01N33/54366 , G06N20/00 , G16H10/40 , G16H50/30 , A61B2010/0067
摘要： Determination system including: a computing device (i) obtaining information related to an eye of a target person from a plurality of data sources and (ii) making a determination of a predetermined matter related to the target person based on at least part of the information. The plurality of data sources include two or more of a sensor included in a contact lens of the target person, a sensor included in a storage container of the contact lens, a measurement device which carries out measurement related to the eye of the target person, tear fluid of the target person, a storage solution of the contact lens and, a diagnostic process of the target person.
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公开(公告)号：US20240210734A1
公开(公告)日：2024-06-27
申请号：US18590579
申请日：2024-02-28
发明人： Long Que , Gil Ben-Shlomo , Chao Song
CPC分类号： G02C7/049 , A61B3/16 , A61B5/14507 , A61B5/4839 , A61B5/6821 , A61B90/39 , A61F9/0008 , G02B1/043 , G02B1/10 , A61F2250/0024 , A61F2250/0097
摘要： Various embodiments disclosed relate to contact lens including nanopores. A contact lens can include a nanoporous film including nanopores that are on an inner surface of the contact lens, and a backing lens on the nanoporous film. Various embodiments further include a biomarker-sensing region of the nanoporous film, a drug storage and delivery region of the nanoporous film, or a combination thereof.
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公开(公告)号：US12016691B2
公开(公告)日：2024-06-25
申请号：US16584997
申请日：2019-09-27
发明人： Satoru Suehara , Akihiro Takahashi
CPC分类号： A61B5/208 , A61B5/14507 , A61B5/201 , A61B5/204 , A61B5/6852 , A61B5/7271 , A61B5/743
摘要： A monitoring system which constitutes an oxygen measurement system includes: an oxygen partial pressure calculation unit that calculates an oxygen partial pressure in urine based on an output signal from the oxygen measurement device; a monitor that displays the oxygen partial pressure calculated by the oxygen partial pressure calculation unit; and a display control unit that changes a format of display of the oxygen partial pressure displayed by the monitor according to the flow rate of urine acquired based on the output signal from the oxygen measurement device.
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公开(公告)号：US11980462B2
公开(公告)日：2024-05-14
申请号：US16789316
申请日：2020-02-12
发明人： Joseph Wang , Patrick Mercier
IPC分类号： A61B5/1486 , A61B5/00 , A61B5/145 , A61C19/04 , H01M8/0239 , H01M8/16 , H01M8/22 , A61B10/00 , G01N27/327
CPC分类号： A61B5/1486 , A61B5/14507 , A61B5/6802 , A61B5/682 , A61C19/04 , H01M8/0239 , H01M8/16 , H01M8/22 , A61B5/14532 , A61B5/14546 , A61B5/7225 , A61B10/0051 , A61B2560/0214 , A61B2560/0462 , A61B2562/0295 , G01N27/3272 , Y02E60/50
摘要： Methods, systems, and devices are disclosed mouth-based biosensors and biofuel cells. In one aspect, an electrochemical sensor device for detecting analytes in saliva includes a substrate including an electrically insulative material, a first electrode disposed on the substrate at a first location, in which the first electrode includes a surface including a chemical agent (e.g., a catalyst or a reactant) corresponding to an analyte in saliva; and a second electrode disposed on the substrate at a second location separated from the first electrode by a spacing region, the first and second electrodes capable of sustaining a redox reaction involving the chemical agent and the analyte to produce an electrical signal, such that, when the device is present in the mouth of a user and electrically coupled to an electrical circuit, the device is operable to detect the analyte in the user's saliva.
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公开(公告)号：US11963721B2
公开(公告)日：2024-04-23
申请号：US16961333
申请日：2019-01-11
IPC分类号： A61B3/10 , A61B3/12 , A61B3/14 , A61B5/00 , A61B5/145 , A61B5/1455 , A61B6/03 , G01J3/02 , G06V10/143 , G06V10/60 , G06V20/69 , G06V40/18 , G16H10/40 , G16H30/40 , G16H50/20 , G16H70/60 , G06V10/58
CPC分类号： A61B3/10 , A61B3/12 , A61B3/14 , A61B5/0075 , A61B5/14507 , A61B5/1455 , A61B5/4088 , A61B5/7264 , A61B6/037 , G01J3/0229 , G06V10/143 , G06V10/60 , G06V20/693 , G06V20/695 , G06V40/18 , G16H10/40 , G16H30/40 , G16H50/20 , G16H70/60 , G06V10/58
摘要： The present disclosure relates to a method and a system for quantifying a biomarker of a biological tissue. Two spectral sub-intervals are determined from a plurality of images of the tissue acquired at discrete wavelengths within a main wavelength interval using an imaging sensor in a manner such that the combination of the image data in the at least two spectral sub-intervals are correlated with a clinical variable of interest. The tissue is illuminated using one or more light sources with wavelengths within the at least two spectral sub-intervals. A measurement is of the light reflected by the tissue is acquired using an imaging sensor; and a measure of the biomarker of the tissue is calculated using the acquired measurement. The main wavelength interval is broader than each of the at least two spectral sub-intervals and at least one spectral confounder causing a spectral variability of the acquired image is present in the tissue.
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6.发明公开公开(公告)号：US20240074708A1
公开(公告)日：2024-03-07
申请号：US18459746
申请日：2023-09-01
发明人： In Su Jang , Min Su Kwon , Hee Jung Kwon , Sung Hwan Chung , Eun Hye Im , Ji Won Kye , Eun Hyun Shim , Hee Jin Kim , Mi Rim Kim , Hyun Seok Cho , Dong Cheol Kim
CPC分类号： A61B5/7275 , A61B5/14507 , A61B5/14532 , G16H50/30
摘要： It is disclosed a blood glucose prediction system and method using saliva-based artificial intelligence deep learning technique. According to one example embodiment, a postprandial blood glucose prediction system may comprise a learning modeling unit for learning a glucose change inference model to infer a pattern difference between blood glucose change and salivary glucose change according to eating by considering a physical indicator, and learning a postprandial blood glucose inference model to infer a correlation between postprandial salivary glucose and postprandial blood glucose by considering the pattern difference; a target information acquiring unit for acquiring a physical indicator and postprandial salivary glucose of a target; a pattern difference estimating unit for estimating a pattern difference of the target by using the glucose change inference model with the physical indicator of the target as an input parameter; and a postprandial blood glucose predicting unit for predicting postprandial blood glucose of the target by using the postprandial blood glucose inference model with the postprandial salivary glucose and the estimated pattern difference of the target as an input parameter.
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公开(公告)号：US11883164B2
公开(公告)日：2024-01-30
申请号：US17574447
申请日：2022-01-12
申请人： Dexcom, Inc.
IPC分类号： A61B5/1486 , A61B5/1473 , A61B5/1495 , A61B5/05 , A61B5/1468 , A61B5/145 , A61B5/00 , A61B5/15 , A61B17/34 , A61M5/172 , A61M5/158 , A61M5/142
CPC分类号： A61B5/14532 , A61B5/0002 , A61B5/0004 , A61B5/0031 , A61B5/05 , A61B5/1411 , A61B5/1451 , A61B5/1473 , A61B5/1486 , A61B5/1495 , A61B5/14503 , A61B5/14507 , A61B5/14514 , A61B5/14546 , A61B5/14735 , A61B5/14865 , A61B5/6801 , A61B5/6833 , A61B5/6848 , A61B5/6849 , A61B5/68335 , A61B5/72 , A61B17/3468 , A61B5/14 , A61B5/145 , A61B5/1468 , A61B5/150022 , A61B2017/3492 , A61B2560/0223 , A61B2560/045 , A61B2560/063 , A61B2562/18 , A61M5/14244 , A61M5/1723 , A61M2005/1585 , Y02A90/10
摘要： Systems and methods for processing sensor analyte data are disclosed, including initiating calibration, updating calibration, evaluating clinical acceptability of reference and sensor analyte data, and evaluating the quality of sensor calibration. The sensor can be calibrated using a calibration set of one or more matched sensor and reference analyte data pairs. Reference data resulting from benchtop testing an analyte sensor prior to its insertion can be used to provide initial calibration of the sensor data. Reference data from a short term continuous analyte sensor implanted in a user can be used to initially calibrate or update sensor data from a long term continuous analyte sensor.
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公开(公告)号：US20240000350A1
公开(公告)日：2024-01-04
申请号：US18469257
申请日：2023-09-18
申请人： Medtronic, Inc.
发明人： John E. Burnes , James K. Carney , Jonathan L. Kuhn , Mark J. Phelps , Jesper Svenning Kristensen , Rodolphe Katra
IPC分类号： A61B5/1459 , A61B5/145 , A61B5/00 , A61B5/0205 , A61B5/1473 , A61B5/20 , A61N1/375 , G01N21/64 , A61B5/07
CPC分类号： A61B5/1459 , A61B5/14546 , A61B5/4833 , A61B5/4848 , A61B5/4866 , A61B5/02055 , A61B5/4381 , A61B5/14735 , A61B5/6861 , A61B5/7278 , A61B5/0071 , A61B5/201 , A61N1/3756 , A61B5/0031 , A61B5/686 , A61B5/14507 , G01N21/6428 , A61B5/076 , A61B5/0036 , A61B5/4839 , G01N21/6408 , A61B5/08
摘要： In some examples, a medical system includes a medical device. The medical device may include a housing configured to be implanted in a target site of a patient, a light emitter configured to emit a signal configured to cause a fluorescent marker to emit a fluoresced signal into the target site, and a light detector that may be configured to detect the fluoresced signal. The medical system may include processing circuitry configured to determine a characteristic of the fluorescent marker based on the emitted signal and the fluoresced signal. The characteristic of the fluorescent marker may be indicative of a presence of a compound in the patient, and the processing circuitry may be configured to track the presence of the compound of the patient based on the characteristic of the fluorescent marker.
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公开(公告)号：US11857347B2
公开(公告)日：2024-01-02
申请号：US17787704
申请日：2020-12-17
IPC分类号： A01K11/00 , A61B5/00 , A01K29/00 , A61B5/01 , A61B5/07 , A61B5/145 , A61B5/1459 , A61B5/1495
CPC分类号： A61B5/6861 , A01K29/00 , A61B5/01 , A61B5/073 , A61B5/1459 , A61B5/1495 , A61B5/14507 , A61B5/4238 , A61B2503/40 , A61B2560/0214
摘要： An apparatus for monitoring nutrition, especially fermentation in a rumen of a ruminant, is designed to be orally applied to the ruminant and to stay permanently in the rumen. The apparatus includes: a) at least one sensing unit for sensing a characteristic value of dissolved carbon dioxide in the liquor of rumen and/or reticulum; and b) at least one first communication unit for the wireless communication of data with a respective second communication unit outside the ruminant. The sensing unit includes at least one attenuated total reflectance (ATR) sensor.
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公开(公告)号：US20230404546A1
公开(公告)日：2023-12-21
申请号：US18240083
申请日：2023-08-30
申请人： Fishburne May, LLC
IPC分类号： A61B10/00 , A61B5/145 , A61B5/1473 , A61B5/00
CPC分类号： A61B10/0051 , A61B5/14507 , A61B5/14539 , A61B5/1473 , A61B5/4261 , A61B2010/0003 , A61B2010/0006 , A61B2010/0074 , A61B2562/0295 , A61B5/14546 , A61B5/01
摘要： Bodily fluid indicator devices, systems, and methods are provided. Such devices, systems, and methods can effectively indicate whether the amount of bodily fluid being produced is within a measurable range, or can characterize various components or features of a bodily fluid. In an exemplary embodiment, a bodily fluid indicator device includes a substrate having a surface. Some portions of the surface are covered with a region of absorbent material and other portions of the surface are devoid of the absorbent material. A graduated scale or a reactive feature can be printed on the absorbent material. The device is configured to indicate an amount and/or a composition a bodily fluid present on an area of a patient or subject.
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