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公开(公告)号：US09766247B2
公开(公告)日：2017-09-19
申请号：US14513774
申请日：2014-10-14
Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
Inventor： Eun Joo Song , Hyunjung Lee , Eunmi Ban , Eunice EunKyeong Kim , Young Sook Yoo
CPC classification number: G01N33/68 , G01N33/502 , G01N2500/02
Abstract: Provided are a method of analyzing ubiquitin-proteasome activity with respect to a target polypeptide and a method of screening a ubiquitin-proteasome inhibitor. According to the provided methods, the pattern of lysis of a target polypeptide by a ubiquitin-proteasome in target cells may be quantitatively analyzed in a rapid and highly sensitive way, a ubiquitin-proteasome inhibitor may be screened in a rapid and highly sensitive way, and an anticancer agent and the activity thereof may be rapidly screened.
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公开(公告)号：US11408886B2
公开(公告)日：2022-08-09
申请号：US16427655
申请日：2019-05-31
Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
Inventor： Min-Jung Kang , Byung Hwa Jung , Young Sook Yoo , Thanh Binh Nguyen
Abstract: Provided are a method of screening for novel therapeutic targets to develop therapeutic agents for colon cancer, and prognostic biomarkers for colon cancer treatment which are screened using the same.
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公开(公告)号：US10266568B2
公开(公告)日：2019-04-23
申请号：US14849755
申请日：2015-09-10
Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
Inventor： Min Park , Min-Jung Kang , Byung Hwa Jung , Young Sook Yoo
IPC: C07K7/56 , C07K14/47 , G01N33/68 , G01N33/564 , G01N33/577
Abstract: Rheumatoid arthritis is efficiently diagnosed with improved patient's convenience using a rheumatoid arthritis diagnosis composition and a kit, each including cyclic citrullinated peptide (CCP), a rheumatoid arthritis diagnosis method using the CCP, the rheumatoid arthritis diagnosis composition, or the kit, a method of obtaining information for rheumatoid arthritis diagnosis, and a method of screening a novel diagnostic marker for rheumatoid arthritis.
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