公开(公告)号：US20230226215A1

公开(公告)日：2023-07-20

申请号：US17937437

申请日：2022-09-30

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY ,  REONEBIO

Inventor： In-San KIM ,  Gi-Hoon NAM ,  Yeon-Sun HONG ,  Seong Eon CHO

IPC: A61K47/69 ,  A61K38/18 ,  A61K38/17 ,  A61K35/28 ,  A61P17/02 ,  A61K9/06

CPC classification number: A61K47/6911 ,  A61K38/1808 ,  A61K38/179 ,  A61K38/1796 ,  A61K38/177 ,  A61K38/1774 ,  A61K35/28 ,  A61P17/02 ,  A61K9/06

Abstract: The present invention provides a recombinant exosome comprising a membrane-bound EGF protein on the surface of the recombinant exosome and provides a use of the recombinant exosome.

公开(公告)号：US20240050523A1

公开(公告)日：2024-02-15

申请号：US18447152

申请日：2023-08-09

Applicant: SHIFTBIO INC. ,  KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Gi-Hoon NAM ,  Gi Beom KIM ,  Jae Hyun KIM ,  Yeji LEE ,  Jiyoung GOO ,  Seongeun CHO ,  Cherlhyun JEONG ,  In-San KIM

IPC: A61K38/17 ,  A61K9/127 ,  A61K47/65 ,  A61P1/16 ,  A61P29/00 ,  A61K47/69 ,  A61K47/64

CPC classification number: A61K38/1709 ,  A61K9/127 ,  A61K38/177 ,  A61K47/65 ,  A61P1/16 ,  A61P29/00 ,  A61K47/6911 ,  A61K47/64

Abstract: The present invention generally relates to an extracellular vesicle (EV) comprising a subunit of a heterodimeric transcription factor, an EV polypeptide, and a monomeric cis-cleaving intein and a method of using the EV.

公开(公告)号：US20230381226A1

公开(公告)日：2023-11-30

申请号：US18322723

申请日：2023-05-24

Applicant: SHIFTBIO INC. ,  Korea Institute of Science and Technology

Inventor： In San KIM ,  Seungyoon PARK ,  Gi-Hoon NAM ,  Inkyu LEE

IPC: A61K35/12 ,  C12N15/85 ,  C12N5/00

CPC classification number: A61K35/12 ,  C12N15/85 ,  C12N5/0006 ,  C12N2800/107

Abstract: The present invention provides surface-engineered extracelluar vesicles, compositions comprising the surface-engineered extracelluar vesicles, methods for preparing the surface-engineered extracelluar vesicles, and methods for using the surface-engineered extracelluar vesicles or the compositions.