-
公开(公告)号：US20180003676A1
公开(公告)日：2018-01-04
申请号：US15702062
申请日：2017-09-12
发明人： Young Keun KIM , Jun Hua WU , Ji Hyun MIN , Ji-Sung LEE , Jae-Ho JUNG
CPC分类号： G01N27/72 , A61K49/1827 , A61K49/1851 , A61K49/1866 , A61K49/1875 , C01G45/12 , C01P2002/72 , C01P2002/85 , C01P2004/04 , C01P2004/62 , C01P2004/64 , C01P2006/42 , G01N33/587
摘要： The present invention relates to a magnetic nanoparticle having a Curie temperature which is within a biocompatible temperature range, a method for preparing same, and a nanocomposite and a target substance detection composition comprising the magnetic nanoparticle. As the magnetic nanoparticle of the present invention has a Curie temperature within the temperature range of 0 degrees centigrade to 41 degrees centigrade, the ferromagnetic and paramagnetic properties of the magnetic nanoparticle may be controlled within a biocompatible temperature range at a temperature at which a biological control agent is not destroyed, and the temperature of the magnetic nanoparticle is adjusted to control the magnetic properties thereof such that the properties of the magnetic nanoparticle may be used only when ferromagnetic properties are required, such as in the case of signal amplification in detecting, separating, and delivering biological control agents. Accordingly, the magnetic nanoparticle of the present invention can minimize adverse effects of ferromagnetic properties thereof, and can be used in the effective detection and separation of biological control agents.
-
公开(公告)号：US20170095579A1
公开(公告)日：2017-04-06
申请号：US15335896
申请日：2016-10-27
发明人： Young Keun KIM , Jun Hua WU , Ji Hyun MIN , Ji-Sung LEE , Jae-Ho JUNG , Woo Seung HAM
CPC分类号： G01N27/72 , A61K49/0032 , A61K49/0041 , A61K49/0058 , A61K49/0093 , C01G45/12 , C01P2002/72 , C01P2004/04 , C01P2004/64 , C01P2006/42 , G01N33/5375 , G01N33/5434 , G01N33/587
摘要： The present invention relates to a composition for target substance detection using a magnetic nanoparticle having a Curie temperature which is within a biocompatible temperature range, a target substance detection system, and a method for obtaining an image of a living body or specimen. As the magnetic nanoparticle of the present invention has a Curie temperature within the temperature range of 0° C. to 41° C., the ferromagnetic and paramagnetic properties of the magnetic nanoparticle may be controlled within a biocompatible temperature range at a temperature at which a biological control agent is not destroyed, and the temperature of the magnetic nanoparticle is adjusted to control the magnetic properties thereof such that the properties of the magnetic nanoparticle may be used only when ferromagnetic properties are required, such as in the case of signal amplification in detecting, separating, and delivering biological control agents. Accordingly, the present invention can provide a biological substance detection system which satisfies both a decrease in non-specific binding and signal amplification using a magnetic nanoparticle having a Curie temperature which is within a biocompatible temperature range, and can be reused after detection.
-
搜索结果
2 条记录 (耗时 0.015 秒)
