摘要:
The present invention relates to a spacer, such as a polymeric spacer, for use with an implant device, e.g., a bone plate, for splinting a fracture of a bone. The spacer includes a body defining a bone healing surface, wherein at least a portion of the bone healing surface has a coating which includes a therapeutic agent, a polymeric carrier, and a buffer medium to stimulate bone growth and/or promote fracture healing. A kit is also disclosed which includes one or more of the spacers, at least one bone plate, and optionally one or more bone screws for securing the bone plate to bone. A method for promoting fracture healing in bone is further disclosed which includes securely situating a coated portion of the spacer adjacent bone.
摘要:
The present invention relates to a spacer, such as a polymeric spacer, for use with an implant device, e.g., a bone plate, for splinting a fracture of a bone. The spacer includes a body defining a bone healing surface, wherein at least a portion of the bone healing surface has a coating which includes a therapeutic agent, a polymeric carrier, and a buffer medium to stimulate bone growth and/or promote fracture healing. A kit is also disclosed which includes one or more of the spacers, at least one bone plate, and optionally one or more bone screws for securing he bone plate to bone. A method for promoting fracture healing in bone is further disclosed which includes securely situating a coated portion of the spacer adjacent bone.
摘要:
A birefringent device, which is configured to be mounted in an optical path of an optical system, has an effective area in a pupil plane. The birefringent device affects different polarization states differently and position-dependently. The birefringent device realizes a first pupil function assigned to a first polarization state and a second different pupil function assigned to a second polarization state. The pupil functions may be optimized to achieve various specific optical properties like extended depth of field.
摘要:
An intramedullary implantation system includes a nail with a head having a first locking element. A targeting guide includes a tubular body and a bore with first and second open ends. A locking device includes a shaft with a distal end having a non-threaded second locking element such that the locking device has a first angular orientation relative to the tubular body in which the first and second locking elements are engaged to secure the nail to the targeting guide. The locking device has a second angular orientation relative to the tubular body in which the first locking element is disengaged from the second locking element.