公开(公告)号：US4734361A

公开(公告)日：1988-03-29

申请号：US877848

申请日：1986-06-24

Applicant: Kanehisa Murao ,  Tsuyoshi Takahashi ,  Tsutomu Kaneko

Inventor： Kanehisa Murao ,  Tsuyoshi Takahashi ,  Tsutomu Kaneko

IPC: A23C9/123 ,  C12Q1/04 ,  C12N1/20 ,  C12N1/36 ,  C12R1/225

CPC classification number: C12R1/225 ,  A23C9/1234 ,  A23C9/1238 ,  Y10S435/853

Abstract: The novel variant Lactobacillus bulgaricus sensitive at a lower temperature, that is, showing a weak tendency towards formation of lactic acid in a range of the lower temperature, and the method for the selection of the variant, are disclosed. By employing the variant, it is possible to produce a fermented milk or lactic acid beverage in which the rate of increase in the sour taste after preservation at a lower temperature is significantly lowered.Cultures of the variant Lactobacillus bulgaricus have been deposited with the Fermentation Research Institute, Agency of Industrial Science and Technology and accorded the number of FERM BP-1041.

Abstract translation: 公开了在较低温度下敏感的保加利亚乳杆菌新型变体，即在较低温度范围内显示出弱酸形成的倾向，以及选择该变体的方法。 通过使用该变型，可以制造发酵乳或乳酸饮料，其中在较低温度下保存后的酸味的增加率显着降低。 变种保加利亚乳杆菌的培养物已经保藏在发酵研究所，工业科学和技术局，并符合FERM BP-1041的数量。

公开(公告)号：US20070292457A1

公开(公告)日：2007-12-20

申请号：US11576032

申请日：2005-10-11

Applicant: Yoshio Toyama ,  Kanehisa Murao

Inventor： Yoshio Toyama ,  Kanehisa Murao

IPC: A61K9/107 ,  A61K47/36 ,  A61P1/00

CPC classification number: A23L33/40 ,  A23V2002/00 ,  A23V2250/5114 ,  A23V2250/54246 ,  A23V2250/50366 ,  A23V2250/50364

Abstract: A object of the present invention is to provide a novel system whereby an enteral nutrient or an enriched liquid food can be solidified so that it can be easily administered within a short period of time without liguefying in the body to thereby lighten a care-giver's burden in tube feeding such as gastrostomic feeding. As the results of studies, it is found out that such a nutrient or an enriched liquid food can be quickly thickened or solidified at a temperature of 40° C. or below by using a starch adhesive, which contains as the main component sodium iota-carrageenan, sodium kappa-carrageenan, sodium lambda-carrageenan or a mixture thereof, without dissolving the starch adhesive by heating. Further, it was confirmed that it is an administration method almost free from water liberation when the solidified product was administered from a syringe, thus the present invention was completed. That is, the use of the above carrageenan as a starch adhesive (a semi-solidifying agent) makes it possible to produce the desired semi-solidified enteral nutrient as described above.

Abstract translation: 本发明的目的是提供一种新颖的系统，其中肠内营养物质或富含液体的食物可被固化，使得其可以在短时间内容易地施用，而不会引起身体损伤，从而减轻护理人员的负担 管饲，如胃食管饲。 作为研究结果，发现通过使用淀粉粘合剂，可以在40℃以下的温度下快速增稠或固化这样的营养物或富集的液体食品，淀粉粘合剂含有作为主要成分的碘酸钠， 角叉菜胶，角叉菜胶卡钠钠，λ-角叉菜胶钠或其混合物，不通过加热溶解淀粉粘合剂。 此外，确认当从注射器给药固化产品时，几乎没有水分释放的给药方法，从而完成了本发明。 也就是说，使用上述角叉菜胶作为淀粉粘合剂（半固化剂）使得可以如上所述生产所需的半固化肠内营养物。