摘要:
The above-described methods and apparatus are believed to be of particular benefit for patients suffering heart failure including cardiac dysfunction, chronic HF, and the like and all variants as described herein and including those known to those of skill in the art to which the invention is directed. It will understood that the present invention offers the possibility of monitoring and therapy of a wide variety of acute and chronic cardiac dysfunctions. The current invention provides systems and methods for delivering therapy for cardiac hemodynamic dysfunction via the innervated myocardial substrate receives one or more discrete pulses of electrical stimulation during the refractory period of said innervated myocardial substrate.
摘要:
An extra-systolic stimulation (ESS) therapy addresses cardiac dysfunction including heart failure. ESS therapy employs atrial and/or ventricular extra-systoles via pacing-level stimulation to a heart. These extra-systoles must be timed correctly to achieve beneficial effects on myocardial mechanics (efficacy) while maintaining an extremely low level of risk of arrhythmia induction and excellent ICD-like arrhythmia sensing and detection (security). The present invention relates to therapy delivery guidance and options for improved ESS therapy delivery. These methods may be employed individually or in combinations in an external or implantable ESS therapy delivery device.
摘要:
An implantable medical device is configured so that all of the major components including a housing and attached leads are disposed within the vasculature of a patient. A tether extends from the housing of the device to an implant location where the tether is secured to tissue outside of the vasculature. In this manner, an intravascular medical device may be implanted at a location remote from final placement, delivered via the vasculature and anchored at the initial entry point.
摘要:
An implantable medical device is configured so that all of the major components including a housing and attached leads are disposed within the vasculature of a patient. A tether extends from the housing of the device to an implant location where the tether is secured to tissue outside of the vasculature. In this manner, an intravascular medical device may be implanted at a location remote from final placement, delivered via the vasculature and anchored at the initial entry point.
摘要:
An implantable medical device is configured so that all of the major components including a housing and attached leads are disposed within the vasculature of a patient. A tether extends from the housing of the device to an implant location where the tether is secured to tissue outside of the vasculature. In this manner, an intravascular medical device may be implanted at a location remote from final placement, delivered via the vasculature and anchored at the initial entry point.
摘要:
Technologies are presented that provide automated non-monetary bidding based on bidder-specific data. A method includes receiving, from a bid acceptance server, an information request associated with a bidder; collecting and analyzing data regarding one or more data points associated with the bidder and requested in the information request; packaging analysis results into a bid; and providing the bid to the bid acceptance server. The data points may be limited based on input from the bidder. The data analyzed may include electronically-available data associated with the bidder. The method may be performed at the bid acceptance server, at a device of a bidder, or at a combination of the two. Submitted bids may be ranked by the bid acceptance server according to a given algorithm.
摘要:
An integrated bipolar implantable medical electrical lead, which may be employed by a cardiac defibrillator, has a single low voltage electrode and a single high voltage electrode and employs a relatively robust and fail-safe configuration of three conductors. Each of the three conductors extends within an individual lumen of a tri-lumen insulative body of the lead. First and second conductors of the three connect, in parallel, the low voltage electrode to a first contact of a connector terminal assembly of the lead, and a third conductor of the three connects the high voltage electrode to a second and a third contact of the connector terminal assembly. A configuration of the third conductor differs from that of the first and second conductors in order to make the third conductor more susceptible to fracture, relative to the first and second conductors, after many years of chronic implant under extreme loading conditions.
摘要:
A casing pipe and drill rod handler for joining the drill rod in a casing pipe. A pipe sled is provided on a drilling rig, the pipe sled comprising an elongated track with a cart slidably mounted on the track to accommodate the casing pipe. A drill rod guide is provided at one end of the track to guide a drill rod as it is positioned and then inserted into the casing pipe.
摘要:
A barrel system for a paintball marker including a breach removably connected to the paintball marker and a composite front detachably connected to the breach. The composite front of the barrel system includes a hollow bore through which a paintball is propelled, a non-metallic inner layer surrounding the bore, and a non-metallic outer layer surrounding the inner layer. The non-metallic inner layer is preferably manufactured from a plurality of unidirectional graphite fibers embedded within an epoxy resin. The non-metallic outer layer is preferably manufactured from a plurality of graphite fibers that are woven together and embedded with an epoxy resin for surrounding and reinforcing the inner layer. The non-metallic inner layer of the composite front is smoothly and continuously tapered to cause the hollow bore to be tapered from a relatively narrow diameter to a relatively wide diameter in the direction of travel of the paintball.
摘要:
The present invention is a sweeper incorporating multiple rotation elements mounted adjacently in an rotationally offset sequence on a common driven axle. Each rotation element comprises a central shaft support from which extends lightweight extension arms that have laterally elongated spatulate paddles at their ends. The extension arms may be curved so that in operation a terminal edge of each paddle lags the rest of the paddle surface in approaching and sweeping across the floor surface and is quite easily deflected upward from a floor surface.