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公开(公告)号：US20080032992A1
公开(公告)日：2008-02-07
申请号：US11772264
申请日：2007-07-02
IPC分类号： A61K31/497 , A61K31/454 , A61P7/02 , C07D401/14
CPC分类号： C07D401/12 , C07D401/14 , C07D413/04 , C07D413/14
摘要： The present invention relates to certain new pyridin analogues of Formula (I) to processes for preparing such compounds, to their utility as P2Y12 inhibitors and as anti-thrombotic agents etc, their use as medicaments in cardiovascular diseases as well as pharmaceutical compositions containing them.
摘要翻译： 本发明涉及式（I）的某些新的吡啶类似物，用于制备此类化合物的方法，其用途为P2Y 12 N抑制剂和作为抗血栓形成剂等，它们用作心血管疾病中的药物 以及含有它们的药物组合物。
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公开(公告)号：US20080200448A1
公开(公告)日：2008-08-21
申请号：US11972876
申请日：2008-01-11
申请人： Thomas Antonsson , Peter Bach , Kay Brickmann , Ruth Bylund , Fabrizio Giordanetto , Johan Johansson , Fredrik Zetterberg
发明人： Thomas Antonsson , Peter Bach , Kay Brickmann , Ruth Bylund , Fabrizio Giordanetto , Johan Johansson , Fredrik Zetterberg
IPC分类号： A61K31/4427 , C07D401/04 , A61K31/4439 , A61K31/4545 , A61P7/02
CPC分类号： C07D401/04 , C07D401/14 , C07D405/14 , C07D417/14 , C07F7/0812
摘要： The present invention relates to certain new pyridin analogues of Formula (I) to processes for preparing such compounds, to their utility as P2Y12 inhibitors and as anti-trombotic agents etc, their use as medicaments in cardiovascular diseases as well as pharmaceutical compositions containing them.
摘要翻译： 本发明涉及式（I）的某些新的吡啶类似物，用于制备此类化合物的方法，其用途为P2Y 12 N抑制剂和抗血栓形成剂等，它们用作心血管疾病中的药物 以及含有它们的药物组合物。
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公开(公告)号：US20080176827A1
公开(公告)日：2008-07-24
申请号：US11972654
申请日：2008-01-11
申请人： Thomas Antonsson , Peter Bach , Kay Brickmann , Ruth Bylund , Fabrizio Giordanetto , Johan Johansson , Fredrik Zetterberg
发明人： Thomas Antonsson , Peter Bach , Kay Brickmann , Ruth Bylund , Fabrizio Giordanetto , Johan Johansson , Fredrik Zetterberg
IPC分类号： A61K31/397 , C07D211/00 , A61K31/445 , C07D401/04 , A61P9/00 , A61K31/4439 , A61K31/4427
CPC分类号： C07D401/04
摘要： The present invention relates to certain new pyridin analogues of Formula (I) to processes for preparing such compounds, to their utility as P2Y12 inhibitors and as anti-trombotic agents etc, their use as medicaments in cardiovascular diseases as well as pharmaceutical compositions containing them.
摘要翻译： 本发明涉及式（I）的某些新的吡啶类似物，用于制备此类化合物的方法，其用途为P2Y 12 N抑制剂和抗血栓形成剂等，它们用作心血管疾病中的药物 以及含有它们的药物组合物。
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公开(公告)号：US20090318464A1
公开(公告)日：2009-12-24
申请号：US12307279
申请日：2007-07-02
IPC分类号： A61K31/497 , C07D409/14 , C07D211/84 , A61K31/4545 , A61P7/04
CPC分类号： C07D401/12 , C07D401/14 , C07D413/04 , C07D413/14
摘要： The present invention relates to certain new pyridin analogues of Formula (I) to processes for preparing such compounds, to their utility as P2Y12 inhibitors and as anti-trombotic agents etc, their use as medicaments in cardiovascular diseases as well as pharmaceutical compositions containing them.
摘要翻译： 本发明涉及式（I）的某些新的吡啶类似物，用于制备这些化合物的方法，其用作P2Y12抑制剂和抗血栓形成剂等，它们作为心血管疾病中的药物的用途以及含有它们的药物组合物。
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公开(公告)号：US20110059981A9
公开(公告)日：2011-03-10
申请号：US12307279
申请日：2007-07-02
IPC分类号： A61K31/497 , C07D409/14 , C07D211/84 , A61K31/4545 , A61P7/04
CPC分类号： C07D401/12 , C07D401/14 , C07D413/04 , C07D413/14
摘要： The present invention relates to certain new pyridin analogues of Formula (I) to processes for preparing such compounds, to their utility as P2Y12 inhibitors and as anti-trombotic agents etc, their use as medicaments in cardiovascular diseases as well as pharmaceutical compositions containing them.
摘要翻译： 本发明涉及式（I）的某些新的吡啶类似物，用于制备这些化合物的方法，其用作P2Y12抑制剂和抗血栓形成剂等，它们作为心血管疾病中的药物的用途以及含有它们的药物组合物。
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公开(公告)号：US20090227555A2
公开(公告)日：2009-09-10
申请号：US11813289
申请日：2008-06-23
申请人： Peter Bach , Jonas Bostrom , Kay Brickmann , Leifeng Cheng , Fabrizio Giordanetto , Robert Groneberg , Darren Harvey , Michael O'Sullivan , Fredrik Zetterberg
发明人： Peter Bach , Jonas Bostrom , Kay Brickmann , Leifeng Cheng , Fabrizio Giordanetto , Robert Groneberg , Darren Harvey , Michael O'Sullivan , Fredrik Zetterberg
IPC分类号： A61K31/496 , C07D487/04 , A61K31/4439 , C07D401/04 , C12N5/06 , A61K31/551 , A61K31/4545
CPC分类号： C07D413/14 , C07D401/04 , C07D401/14 , C07D405/14 , C07D409/12 , C07D409/14 , C07D413/12 , C07D417/14
摘要： The present invention relates to certain novel pyridin compounds of Formula (I) to processes for preparing such compounds, to their utility as P2Y12 inhibitors and as anti-thrombotic agents etc, and processes for their preparation, their use as medicaments in cardiovascular diseases as well as pharmaceutical compositions containing them.
摘要翻译： 本发明涉及式（I）的某些新的吡啶化合物，用于制备这些化合物的方法，其作为P2Y12抑制剂和抗血栓形成剂等的用途及其制备方法，它们作为心血管疾病的药物 作为含有它们的药物组合物。
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公开(公告)号：US20090042852A1
公开(公告)日：2009-02-12
申请号：US11813289
申请日：2006-01-04
申请人： Peter Bach , Jonas Bostrom , Kay Brickmann , Leifeng Cheng , Fabrizio Giordanetto , Robert D. Groneberg , Darren Martin Harvey , Michael F. O'Sullivan , Fredrik Zetterberg , Krister Osterlund
发明人： Peter Bach , Jonas Bostrom , Kay Brickmann , Leifeng Cheng , Fabrizio Giordanetto , Robert D. Groneberg , Darren Martin Harvey , Michael F. O'Sullivan , Fredrik Zetterberg , Krister Osterlund
IPC分类号： A61K31/496 , C07D487/04 , A61K31/4439 , C07D401/04 , C12N5/06 , A61K31/551 , A61K31/4545
CPC分类号： C07D413/14 , C07D401/04 , C07D401/14 , C07D405/14 , C07D409/12 , C07D409/14 , C07D413/12 , C07D417/14
摘要： The present invention relates to certain novel pyridin compounds of Formula (I) to processes for preparing such compounds, to their utility as P2Y12 inhibitors and as anti-trombotic agents etc, and processes for their preparation, their use as medicaments in cardiovascular diseases as well as pharmaceutical compositions containing them.
摘要翻译： 本发明涉及式（I）的某些新颖的吡啶化合物，用于制备这些化合物的方法，其用途为P2Y12抑制剂和抗血栓形成剂等，及其制备方法，它们用作心血管疾病中的药物 作为含有它们的药物组合物。
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公开(公告)号：US20080312208A1
公开(公告)日：2008-12-18
申请号：US11995326
申请日：2006-07-04
申请人： Soren Andersen , Peter Bach , Kay Brickmann , Fabrizio Giordanetto , Fredrik Zetterberg , Krister Osterlund
发明人： Soren Andersen , Peter Bach , Kay Brickmann , Fabrizio Giordanetto , Fredrik Zetterberg , Krister Osterlund
IPC分类号： A61K31/4427 , A61K31/496 , C07D401/04 , A61K31/4545 , A61P7/02
CPC分类号： C07D401/04 , C07D213/85 , C07D213/89 , C07D401/14 , C07D409/14 , C07D413/14
摘要： The present invention relates to certain new pyridin analogues of Formula (I) Chemical formula should be inserted here. Please see paper copy Formula (I) to processes for preparing such compounds, to their utility as P2Y12 inhibitors and as anti-thrombotic agents etc, their use as medicaments in cardiovascular diseases as well as pharmaceutical compositions containing them.
摘要翻译： 本发明涉及某些式（I）的新的吡啶类似物，此处应插入化学式。 请参阅纸（I）的制备这些化合物的方法，其作为P2Y12抑制剂和抗血栓形成剂的用途，它们作为心血管疾病药物的用途以及含有它们的药物组合物。
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公开(公告)号：US20080300232A1
公开(公告)日：2008-12-04
申请号：US10599110
申请日：2005-03-21
申请人： Kay Brickmann , Bryan J. Egner , Fabrizio Giordanetto , Tord Inghardt , Anna Linusson Jonsson , Fritiof Ponten
发明人： Kay Brickmann , Bryan J. Egner , Fabrizio Giordanetto , Tord Inghardt , Anna Linusson Jonsson , Fritiof Ponten
IPC分类号： A61K31/397 , C07D401/02 , A61K31/454 , C07D213/02 , A61P3/04 , A61P3/10 , A61P25/00 , A61K31/4545 , C07D239/24 , A61K31/506
CPC分类号： C07D403/06 , C07D401/06 , C07D401/10 , C07D401/14 , C07D405/06 , C07D405/14 , C07D409/14
摘要： Compounds of formula I, processes for preparing such compounds, their use in the treatment of obesity, psychiatric disorders, cognitive disorders, memory disorders, schizophrenia, epilepsy, and related conditions, and neurological disorders such as dementia, multiple sclerosis, Parkinson's disease, Huntington's chorea and Alzheimer's disease and pain related disorders and to pharmaceutical compositions containing them.
摘要翻译： 式I化合物，制备这些化合物的方法，它们在治疗肥胖，精神障碍，认知障碍，记忆障碍，精神分裂症，癫痫和相关病症中的用途，以及神经障碍如痴呆，多发性硬化，帕金森病，亨廷顿病 舞蹈病和阿尔茨海默病和疼痛相关疾病以及含有它们的药物组合物。
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公开(公告)号：US20100137277A1
公开(公告)日：2010-06-03
申请号：US12522724
申请日：2008-01-11
申请人： Thomas Antonsson , Peter Bach , David Brown , Ruth Bylund , Fabrizio Giordanetto , Johan Johansson
发明人： Thomas Antonsson , Peter Bach , David Brown , Ruth Bylund , Fabrizio Giordanetto , Johan Johansson
IPC分类号： A61K31/397 , C07D401/04 , A61K31/4545 , A61P7/02 , A61K31/4439
CPC分类号： C07D401/04 , C07D413/14
摘要： The present invention relates to certain new pyridin analogues of Formula (I) to processes for preparing such compounds, to their utility as P2Y12 inhibitors and as anti-trombotic agents etc, their use as medicaments in cardiovascular diseases as well as pharmaceutical compositions containing them.
摘要翻译： 本发明涉及式（I）的某些新的吡啶类似物，用于制备这些化合物的方法，其作为P2Y12抑制剂和抗血栓形成剂的用途，其作为心血管疾病中的药物的用途以及含有它们的药物组合物。
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