公开(公告)号：US20100316542A1

公开(公告)日：2010-12-16

申请号：US12814155

申请日：2010-06-11

申请人： Kazunori MOTOTSU ,  Toshikatsu Fukuju ,  Hiroto Toyoshima

发明人： Kazunori MOTOTSU ,  Toshikatsu Fukuju ,  Hiroto Toyoshima

IPC分类号： B01L3/02

CPC分类号： B01L3/0275 ,  B01L9/543 ,  B01L2300/0858

摘要： The present invention is to present a disposable pipette tip used in a dispensing device, comprising: an attachment section for being attached to the dispensing device; and a liquid containing section for containing a liquid aspirated by the dispensing device, which is continually located to the attachment section and comprises a first part and a second part being continually located to the first part on the attachment section side, wherein the first part comprises a tip portion, an intermediate portion and a stepped portion, the tip portion including a distal end of the pipette tip, the intermediate portion continually located to the tip portion and the second part, the tip portion having an external diameter that decreases toward the distal end, and the intermediate portion having an external diameter that decreases toward the tip portion; the stepped portion is formed at a connecting position of the tip portion and the intermediate portion such that the external diameter of the intermediate portion at the connecting position is larger than that of the tip portion at the connecting position, the connecting position being closer to the distal end than the second part; the second part has an internal diameter that decreases toward the first part; the external diameter of the intermediate portion at the connecting position is larger than the internal diameter of an end of the second part on the first part side; the external diameter of the tip portion at the connecting position is smaller than the internal diameter of the end of the second part on the first part side; and length from the end of the second part on the first part side to the end of the attachment section on the opposite side of the second part is not less than twice but not more than four times as large as that of the tip portion.

摘要翻译： 本发明提供一种用于分配装置中的一次性移液管吸头，包括：用于附接到分配装置的附接部分; 以及液体容纳部分，用于容纳由所述分配装置吸入的液体，所述液体连续地位于所述附接部分上，并且包括第一部分和第二部分，其连续地位于所述附接部分侧上的所述第一部分，其中所述第一部分包括 尖端部分，中间部分和阶梯部分，所述尖端部分包括所述移液管末端的远端，所述中间部分连续地位于所述尖端部分和所述第二部分，所述尖端部分具有朝向远端 并且所述中间部分具有朝向所述末端部分减小的外径; 台阶部分形成在前端部分和中间部分的连接位置处，使得连接位置处的中间部分的外径大于连接位置处的末端部分的外径，连接位置更靠近 远端比第二部分; 第二部分具有朝向第一部分减小的内径; 连接位置处的中间部的外径大于第一部分侧的第二部分的端部的内径; 连接位置处的前端部的外径小于第一部分侧的第二部分的端部的内径; 并且从第二部分的第二部分的端部到第二部分的相对侧上的连接部分的端部的长度不小于末端部分的两倍但不超过四倍。

公开(公告)号：US20070231215A1

公开(公告)日：2007-10-04

申请号：US11730471

申请日：2007-04-02

申请人： Kazunori Mototsu ,  Toshikatsu Fukuju ,  Hiroto Toyoshima

发明人： Kazunori Mototsu ,  Toshikatsu Fukuju ,  Hiroto Toyoshima

IPC分类号： B01L3/02

CPC分类号： B01L3/0275 ,  B01L9/543 ,  B01L2300/0858

摘要： The present invention is to present a disposable pipette tip that can easily prevent a tight fit with another pipette tip without providing a separating mechanism in a supplying apparatus. The disposable pipette tip comprises: an attachment section for being attached to the dispensing device; and a liquid containing section for containing a liquid aspirated by the dispensing device, which is continually located to the attachment section, has a tapered distal end and comprises a tight fit preventing part which is located adjacent to the tapered distal end and prevents a tight fit with another pipette tip.

摘要翻译： 本发明提供一种一次性吸头，其可以容易地防止与另一移液管尖紧密配合，而不在供应装置中提供分离机构。 一次性移液管尖端包括：用于附接到分配装置的附接部分; 以及用于容纳由分配装置吸取的液体的液体容纳部分，其连续地位于附接部分，具有锥形远端，并且包括紧密配合防止部分，其紧邻锥形远端定位，并防止紧密配合 与另一个移液器提示。

公开(公告)号：US10107829B2

公开(公告)日：2018-10-23

申请号：US13315862

申请日：2011-12-09

申请人： Hiroto Toyoshima ,  Kazunori Mototsu

发明人： Hiroto Toyoshima ,  Kazunori Mototsu

IPC分类号： G01N35/00 ,  G01N27/74

摘要： The present invention is to present an analyzing method for analyzing a target substance contained in a sample using a reagent containing magnetic particles. The method comprises steps of: (a) magnetically capturing magnetic particles in a container with a first magnetic force generating member arranged on a lower side of the container accommodating a liquid specimen containing the magnetic particles; (b) transferring the container to a target substance separating section after the step (a); and (c) in the target substance separating section, discharging a cleaning liquid into the container and aspirating a liquid in the container while magnetically capturing the magnetic particles in the container with a second magnetic force generating member.

公开(公告)号：US09229018B2

公开(公告)日：2016-01-05

申请号：US13315884

申请日：2011-12-09

申请人： Hiroto Toyoshima ,  Kazunori Mototsu

发明人： Hiroto Toyoshima ,  Kazunori Mototsu

IPC分类号： G01N1/18 ,  G01N35/00 ,  G01N35/10

CPC分类号： G01N35/0098 ,  B03C1/01 ,  B03C1/0332 ,  B03C1/288 ,  B03C2201/18 ,  B03C2201/26 ,  G01N35/1002 ,  Y10T436/25375

摘要： The present invention is to present a sample analyzer for analyzing a target substance in a sample by carrying out a target substance separating process for separating a complex containing the target substance and a magnetic particle from other substances other than the complex. The sample analyzer executes the target substance separating process with respect to a second container held by a second holder with a second nozzle while executing the target substance separating process with respect to a first container held by a first holder with a first nozzle, and completes the target substance separating process with respect to the first container with the first nozzle and completes the target substance separating process with respect to the second container with the second nozzle.

摘要翻译： 本发明提供一种用于分析样品中的目标物质的样品分析装置，其通过进行用于从复合物以外的其它物质分离含有目标物质和磁性粒子的复合物的目标物质分离方法。 样品分析装置对由具有第二喷嘴的第二保持器保持的第二容器执行目标物质分离处理，同时对具有第一喷嘴的第一保持器保持的第一容器执行目标物质分离处理，并且完成 相对于具有第一喷嘴的第一容器的目标物质分离处理，并且利用第二喷嘴完成相对于第二容器的目标物质分离处理。

公开(公告)号：US20120149132A1

公开(公告)日：2012-06-14

申请号：US13315862

申请日：2011-12-09

申请人： Hiroto Toyoshima ,  Kazunori Mototsu

发明人： Hiroto Toyoshima ,  Kazunori Mototsu

IPC分类号： G01N33/50

CPC分类号： G01N35/0098 ,  B03C1/01 ,  B03C1/0332 ,  B03C1/288 ,  B03C2201/18 ,  B03C2201/26 ,  G01N27/745

摘要： The present invention is to present an analyzing method for analyzing a target substance contained in a sample using a reagent containing magnetic particles. The method comprises steps of: (a) magnetically capturing magnetic particles in a container with a first magnetic force generating member arranged on a lower side of the container accommodating a liquid specimen containing the magnetic particles; (b) transferring the container to a target substance separating section after the step (a); and (c) in the target substance separating section, discharging a cleaning liquid into the container and aspirating a liquid in the container while magnetically capturing the magnetic particles in the container with a second magnetic force generating member.

摘要翻译： 本发明是提供使用含有磁性粒子的试剂来分析样品中所含有的目标物质的分析方法。 该方法包括以下步骤：（a）磁性捕获容器中的磁性颗粒，其中第一磁力产生元件布置在容器的下侧，容纳含有磁性颗粒的液体样本; （b）在步骤（a）之后将容器转移到目标物质分离部分; 和（c）在目标物质分离部分中，用第二磁力产生部件磁性捕获容器内的磁性颗粒，将清洗液排放到容器中并吸入容器中的液体。

公开(公告)号：US20120149127A1

公开(公告)日：2012-06-14

申请号：US13315884

申请日：2011-12-09

申请人： Hiroto Toyoshima ,  Kazunori Mototsu

发明人： Hiroto Toyoshima ,  Kazunori Mototsu

IPC分类号： G01N1/18

CPC分类号： G01N35/0098 ,  B03C1/01 ,  B03C1/0332 ,  B03C1/288 ,  B03C2201/18 ,  B03C2201/26 ,  G01N35/1002 ,  Y10T436/25375

摘要： The present invention is to present a sample analyzer for analyzing a target substance in a sample by carrying out a target substance separating process for separating a complex containing the target substance and a magnetic particle from other substances other than the complex. The sample analyzer executes the target substance separating process with respect to a second container held by a second holder with a second nozzle while executing the target substance separating process with respect to a first container held by a first holder with a first nozzle, and completes the target substance separating process with respect to the first container with the first nozzle and completes the target substance separating process with respect to the second container with the second nozzle.

摘要翻译： 本发明提供一种用于分析样品中的目标物质的样品分析装置，其通过进行用于从复合物以外的其它物质分离含有目标物质和磁性粒子的复合物的目标物质分离方法。 样品分析装置对由具有第二喷嘴的第二保持器保持的第二容器执行目标物质分离处理，同时对具有第一喷嘴的第一保持器保持的第一容器执行目标物质分离处理，并且完成 相对于具有第一喷嘴的第一容器的目标物质分离处理，并且利用第二喷嘴完成相对于第二容器的目标物质分离处理。

公开(公告)号：US09285383B2

公开(公告)日：2016-03-15

申请号：US14024187

申请日：2013-09-11

申请人： Hiroto Toyoshima ,  Kouichi Masutani

发明人： Hiroto Toyoshima ,  Kouichi Masutani

IPC分类号： G01N35/04 ,  G01N35/10

CPC分类号： G01N35/04 ,  G01N2035/0406 ,  G01N2035/0465 ,  G01N2035/103

摘要： A specimen analyzer comprises a measurement mechanism section configured to measure a specimen by using a first consumable and a second consumable having a shape different from a shape of the first consumable, a first inlet for loading the first consumable, a supplying section configured to supply the first consumable loaded through the first inlet, to the measurement mechanism section, a sorter configured to sort the first consumable and the second consumable from each other, and a storage for housing the second consumable sorted by the sorter.

摘要翻译： 一种检体分析装置，其特征在于，包括：测定机构部，其通过使用具有与上述第一消耗品的形状不同的形状的第一消耗品和第二消耗品来测定试样;第一入口，用于装载上述第一消耗品;供给部， 第一消耗品通过第一入口装载到测量机构部分，分类器，其被配置为将第一消耗品和第二消耗品彼此分类;以及存储器，用于容纳由分类器排序的第二消耗品。

公开(公告)号：US20090226344A1

公开(公告)日：2009-09-10

申请号：US12288562

申请日：2008-10-21

申请人： Tomoyuki Nishida ,  Takatomo Kudo ,  Hiroto Toyoshima

发明人： Tomoyuki Nishida ,  Takatomo Kudo ,  Hiroto Toyoshima

IPC分类号： B01J19/00

CPC分类号： G01N35/1011 ,  G01N2035/0491 ,  G01N2035/0494 ,  G01N2035/1013

摘要： A sample analyzer is disclosed which enables to confirm the position of a pipette of dispensing section not depend on instruction directed a start of a position confirmation operation from the operator, and to prevent a pipette from being damaged or credibility of analysis results from declining.Concretely, the sample analyzer comprises a pipette, a pipette moving mechanism and a position confirming member disposed at a position where the pipette can be moved by the pipette moving mechanism. The position confirming member comprises a space into which a tip end of the pipette can be inserted. When the sample analyzer carries out the position confirmation process, the tip end of the pipette is moved by the pipette moving mechanism so as to be inserted into the space of the position confirming member. When a sensor sensed that the tip end of the pipette collides with the position confirming member, the sample analyzer stops the movement of the pipette and notify that the pipette of the pipette moving mechanism has a problem.

摘要翻译： 公开了一种样本分析器，其能够确认分配部分的移液管的位置不依赖于指示来自操作者的开始位置确认操作的指令，并且防止移液管被损坏或分析结果的可信性下降。 具体地，样本分析仪包括移液管，移液管移动机构和设置在移液管能够被移液管移动机构移动的位置的位置确认部件。 位置确认部件包括可以插入移液管的前端的空间。 当样品分析仪进行位置确认处理时，移液管的前端由移液管移动机构移动，以插入位置确认部件的空间。 当传感器感测到移液管的尖端与位置确认部件碰撞时，样品分析仪停止移液管的移动并通知移液管移动机构的移液管有问题。

公开(公告)号：US09255939B2

公开(公告)日：2016-02-09

申请号：US12288562

申请日：2008-10-21

申请人： Tomoyuki Nishida ,  Takatomo Kudo ,  Hiroto Toyoshima

发明人： Tomoyuki Nishida ,  Takatomo Kudo ,  Hiroto Toyoshima

IPC分类号： G01N35/10 ,  G01N35/04

CPC分类号： G01N35/1011 ,  G01N2035/0491 ,  G01N2035/0494 ,  G01N2035/1013

摘要： A sample analyzer comprises a pipette, a pipette moving mechanism and a position confirming member disposed at a position where the pipette can be moved by the pipette moving mechanism. The position confirming member comprises a space into which a tip end of the pipette can be inserted. When the sample analyzer carries out the position confirmation process, the tip end of the pipette is moved by the pipette moving mechanism so as to be inserted into the space of the position confirming member. When a sensor sensed that the tip end of the pipette collides with the position confirming member, the sample analyzer stops the movement of the pipette and notify that the pipette of the pipette moving mechanism has a problem.

摘要翻译： 样品分析器包括移液管，移液管移动机构和位置确认部件，其位于移液管能够被移液管移动机构移动的位置。 位置确认部件包括可以插入移液管的前端的空间。 当样品分析仪进行位置确认处理时，移液管的前端由移液管移动机构移动，以插入位置确认部件的空间。 当传感器感测到移液管的尖端与位置确认部件碰撞时，样品分析仪停止移液管的移动并通知移液管移动机构的移液管有问题。