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公开(公告)号:US07070793B1
公开(公告)日:2006-07-04
申请号:US09509744
申请日:1998-09-28
申请人: Kazutoh Takesako , Shigetoshi Mizutani , Masahiro Endo , Junko Ogawa , Takashi Okado , Ikunoshin Kato
发明人: Kazutoh Takesako , Shigetoshi Mizutani , Masahiro Endo , Junko Ogawa , Takashi Okado , Ikunoshin Kato
CPC分类号: C07K14/40 , A61K38/00 , A61K39/00 , Y10S530/824
摘要: To provide a novel antigenic protein and a nucleic acid encoding the antigenic protein, which are useful for prophylaxis, treatment and diagnosis of diseases caused by fungi including Candida albicans. An antigenic protein characterized in that the antigenic protein is recognized by antiserum derived from a mammal having Candida albicans-infection resistance; and a nucleic acid encoding an antigenic protein which is recognized by antiserum derived from a mammal having Candida albicans-infection resistance.
摘要翻译: 提供新型抗原蛋白和编码抗原蛋白的核酸,其可用于预防,治疗和诊断由真菌引起的疾病,包括白色念珠菌。 一种抗原蛋白,其特征在于抗原蛋白由来自具有白念珠菌感染抗性的哺乳动物的抗血清识别; 以及编码由来自具有白念珠菌感染抗性的哺乳动物的抗血清识别的抗原性蛋白质的核酸。
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公开(公告)号:US20050276821A1
公开(公告)日:2005-12-15
申请号:US11119769
申请日:2005-05-03
申请人: Kazutoh Takesako , Shigetoshi Mizutani , Masahiro Endo , Junko Ogawa , Takashi Okado , Ikunoshin Kato
发明人: Kazutoh Takesako , Shigetoshi Mizutani , Masahiro Endo , Junko Ogawa , Takashi Okado , Ikunoshin Kato
IPC分类号: G01N33/50 , A61K38/00 , A61K39/00 , A61K49/00 , A61P13/02 , A61P15/00 , A61P31/04 , C07K14/40 , C07K16/14 , C12N5/10 , C12N15/09 , C12N15/31 , C12Q1/68 , G01N33/53 , G01N33/569 , C07H21/04 , C12N1/18 , C12N15/74
CPC分类号: C07K14/40 , A61K38/00 , A61K39/00 , Y10S530/824
摘要: To provide a novel antigenic protein and a nucleic acid encoding the antigenic protein, which are useful for prophylaxis, treatment and diagnosis of diseases caused by fungi including Candida albicans. An antigenic protein characterized in that the antigenic protein is recognized by antiserum derived from a mammal having Candida albicans-infection resistance; and a nucleic acid encoding an antigenic protein which is recognized by antiserum derived from a mammal having Candida albicans-infection resistance.
摘要翻译: 提供新型抗原蛋白和编码抗原蛋白的核酸,其可用于预防,治疗和诊断由真菌引起的疾病,包括白色念珠菌。 一种抗原蛋白,其特征在于抗原蛋白由来自具有白念珠菌感染抗性的哺乳动物的抗血清识别; 以及编码由来自具有白念珠菌感染抗性的哺乳动物的抗血清识别的抗原性蛋白质的核酸。
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公开(公告)号:US20090227493A1
公开(公告)日:2009-09-10
申请号:US11915734
申请日:2006-05-26
申请人: Ryutaro Nakashima , Junko Ogawa , Akira Okuno
发明人: Ryutaro Nakashima , Junko Ogawa , Akira Okuno
IPC分类号: A61K38/22 , A61K31/427
CPC分类号: A61K31/427 , A61K38/26 , A61K45/06 , A61K2300/00
摘要: The present invention provides a pharmaceutical composition (preferably a drug for therapeutic and/or prophylactic treatment of diabetes) comprising a GLP-1 receptor agonist and the insulin resistance improving agent 5-[4-(6-methoxy-1-methyl-1H-benzimidazol-2-ylmethoxy)benzyl]thiazolidine-2,4-dione, or a pharmacologically acceptable salt thereof, in combination.
摘要翻译: 本发明提供了包含GLP-1受体激动剂和胰岛素抵抗性改善剂5- [4-(6-甲氧基-1-甲基-1H-苯并咪唑)的药物组合物(优选用于治疗和/或预防性治疗糖尿病的药物) 苯并咪唑-2-基甲氧基)苄基]噻唑烷-2,4-二酮或其药理学上可接受的盐。
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公开(公告)号:US20090137626A1
公开(公告)日:2009-05-28
申请号:US11922670
申请日:2006-07-11
申请人: Akira Okuno , Taishi Yoshida , Junko Ogawa
发明人: Akira Okuno , Taishi Yoshida , Junko Ogawa
IPC分类号: A61K31/47 , A61K31/4439 , A61K31/155 , A61P3/10 , A61K31/192 , A61K31/422
CPC分类号: A61K45/06 , A61K31/155 , A61K31/192 , A61K31/4184 , A61K31/421 , A61K31/425 , A61K31/4439 , A61K31/47
摘要: [Object] To provide a highly safe method for treating diabetes that demonstrates superior effects and is capable of inhibiting adverse side effects.[Means for Solution] A pharmaceutical containing a PPARγ agonist, and a pharmaceutical composition in combination with a biguanide agent and a PPARγ agonist.
摘要翻译: 提供一种高度安全的治疗糖尿病的方法,其表现出优异的效果并且能够抑制不良副作用。 [解决方案]含有PPARγ激动剂的药物,以及与双胍类药剂和PPARγ激动剂组合的药物组合物。
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