Eye lens material and method of manufacturing thereof
    2.
    发明授权
    Eye lens material and method of manufacturing thereof 失效
    眼镜片材料及其制造方法

    公开(公告)号:US08318865B2

    公开(公告)日:2012-11-27

    申请号:US10593682

    申请日:2005-05-18

    IPC分类号: C08C19/24

    摘要: The present invention is a method of manufacturing an eye lens material having a process in which a phosphorylcholine group-containing chemical compound represented by the following formula (1) is reacted and covalently bonded to the surface of an eye lens material having hydroxyl groups wherein the chemical compound represented by the following formula (2) is reacted and covalently bonded through ester-bonding to the eye lens material in an organic solvent.The object of the present invention is to provide an eye lens material that prevents protein adsorption and a method of manufacturing thereof.

    摘要翻译: 本发明是一种眼镜透镜材料的制造方法,其具有下述通式(1)所示的含磷酰胆碱基的化合物与具有羟基的眼晶状体材料的表面反应并共价键合的方法,其中, 由下式(2)表示的化合物通过酯键在有机溶剂中与眼晶体材料反应并共价键合。 本发明的目的是提供一种防止蛋白质吸附的眼用透镜材料及其制造方法。

    Method for producing protein adsorption-preventing ocular lens material
    3.
    发明授权
    Method for producing protein adsorption-preventing ocular lens material 失效
    产生蛋白质吸附防止眼透镜材料的方法

    公开(公告)号:US08277834B2

    公开(公告)日:2012-10-02

    申请号:US10592772

    申请日:2005-05-18

    IPC分类号: A61K31/80

    CPC分类号: C08J7/12 A61F2/16 G02B1/043

    摘要: The present invention is a method of manufacturing an eye lens material having a process in which a phosphorylcholine group-containing chemical compound represented by the following formula (1) is reacted and covalently bonded onto the surface of an eye lens material wherein a chemical compound having an end amino group is introduced to said eye lens material and then the chemical compound represented by the following formula (2) or (3) is introduced through said chemical compound having an end amino group.The object of the present invention is to provide a method of manufacturing a contact lens that prevents protein adsorption.

    摘要翻译: 本发明是一种眼透镜材料的制造方法,其具有以下处理:将由下式(1)表示的含磷酰胆碱基的化合物反应并共价键合到眼晶状体材料的表面上,其中具有 将末端氨基引入所述眼晶状体材料中,然后通过具有末端氨基的化合物引入由下式(2)或(3)表示的化合物。 本发明的目的是提供一种制造防止蛋白质吸附的隐形眼镜的方法。

    Method of manufacturing protein adsorption preventing eye lens material
    4.
    发明授权
    Method of manufacturing protein adsorption preventing eye lens material 失效
    制造蛋白质吸附防眼眼镜材料的方法

    公开(公告)号:US08236873B2

    公开(公告)日:2012-08-07

    申请号:US10593544

    申请日:2005-05-18

    IPC分类号: G02B1/04

    CPC分类号: C08J7/12 A61F2/16 G02B1/043

    摘要: An eye lens material preventing protein adsorption is manufactured by reacting in a reaction medium of either water, an organic solvent, or a water/organic solvent mixture an eye lens material having OH groups with a phosphorylcholine group-containing compound of formula (1), thereby forming an acetal bond according to formula (2) which covalently bonds the phosphorylcholine group-containing compound to a surface of the eye lens material.

    摘要翻译: 通过在水,有机溶剂或水/有机溶剂混合物,具有OH基的眼晶状体材料与含磷酰胆碱基团的式(1)化合物的反应介质中反应来制造防止蛋白质吸附的眼镜片材料, 从而形成根据式(2)的缩醛键,其将含磷酰胆碱基团的化合物共价键合到眼晶状体材料的表面。

    Polysiloxane having phosphorylcholine group and process for producing the same
    6.
    发明授权
    Polysiloxane having phosphorylcholine group and process for producing the same 失效
    具有磷酸胆碱基团的聚硅氧烷及其制造方法

    公开(公告)号:US07875692B2

    公开(公告)日:2011-01-25

    申请号:US10534399

    申请日:2003-11-20

    IPC分类号: C08G77/04 C08G77/26

    摘要: A polysiloxane having a phosphorylcholine group represented by the following general formula (1). To develop a method to obtain a polysiloxane having a phosphorylcholine group with ease and great versatility and provide a polysiloxane having a phosphorylcholine group in order to obtain a polysiloxane that has a wide range of application as a biocompatible material and a cosmetic material.

    摘要翻译: 具有由以下通式(1)表示的磷酸胆碱基的聚硅氧烷。 为了开发获得具有磷酸胆碱基团的聚硅氧烷的方法,并且具有广泛性,并提供具有磷酸胆碱基团的聚硅氧烷,以获得作为生物相容性材料和化妆品材料具有广泛应用的聚硅氧烷。

    Protein Adsorption Prevention Eye Lens Material And Method For Producing Same
    10.
    发明申请
    Protein Adsorption Prevention Eye Lens Material And Method For Producing Same 失效
    蛋白质吸附防护眼镜材料及其制作方法

    公开(公告)号:US20090156741A1

    公开(公告)日:2009-06-18

    申请号:US10593544

    申请日:2005-05-18

    IPC分类号: C08F8/40

    CPC分类号: C08J7/12 A61F2/16 G02B1/043

    摘要: The present invention is a method of manufacturing an eye lens material having a process in which a phosphorylcholine group-containing chemical compound represented by the following formula (1) is reacted and covalently bonded onto the surface of an eye lens material wherein the chemical compound represented by the following formula (2) is reacted and covalently bonded through acetal bonding to the eye lens material having OH groups in water, an organic solvent, or a water/organic solvent mixture.The object of the present invention is to provide an eye lens material that prevents protein adsorption and a method of manufacturing thereof.

    摘要翻译: 本发明是一种眼透镜材料的制造方法,其具有下述式(1)所示的含有磷酰胆碱基的化合物反应并共价结合在眼晶状体材料的表面上的方法,其中, 通过下式(2)通过缩醛键与在水,有机溶剂或水/有机溶剂混合物中具有OH基团的眼晶状体材料反应并共价键合。 本发明的目的是提供一种防止蛋白质吸附的眼用透镜材料及其制造方法。