Methods of recruiting fibroblasts by administering G-CSF
    1.
    发明授权
    Methods of recruiting fibroblasts by administering G-CSF 有权
    通过给予G-CSF募集成纤维细胞的方法

    公开(公告)号:US07531510B2

    公开(公告)日:2009-05-12

    申请号:US10577241

    申请日:2004-10-27

    IPC分类号: A61K38/00 A61K45/00

    CPC分类号: A61K38/193

    摘要: The object of the present invention is to achieve simple recruitment of fibroblasts into wounded tissues and engraftment of the fibroblasts in the wounded tissues, thereby healing the wounds without requiring fibroblast transplantation. Upon G-CSF administration, fibroblasts migrate into myocardial infarct lesions and prevent a reduction in cardiac function, thus alleviating cardiac remodeling.

    摘要翻译: 本发明的目的是实现将伤口组织中的成纤维细胞简单地募集到受伤组织中的成纤维细胞,从而使伤口愈合而不需要成纤维细胞移植。 在G-CSF施用后,成纤维细胞迁移到心肌梗塞病变中并防止心脏功能的降低,从而减轻心脏重塑。

    G-csf-containing substance for fibroblast recruitment and g-csf-contianing therapeutic agent for wound healing
    2.
    发明申请
    G-csf-containing substance for fibroblast recruitment and g-csf-contianing therapeutic agent for wound healing 有权
    用于成纤维细胞募集的含G-csf的物质和用于伤口愈合的g-csf-contianing治疗剂

    公开(公告)号:US20070081970A1

    公开(公告)日:2007-04-12

    申请号:US10577241

    申请日:2004-10-27

    IPC分类号: A61K38/19

    CPC分类号: A61K38/193

    摘要: The object of the present invention is to achieve simple recruitment of fibroblasts into wounded tissues and engraftment of the fibroblasts in the wounded tissues, thereby healing the wounds without requiring fibroblast transplantation. Upon G-CSF administration, fibroblasts migrate into myocardial infarct lesions and prevent a reduction in cardiac function, thus alleviating cardiac remodeling.

    摘要翻译: 本发明的目的是实现将伤口组织中的成纤维细胞简单地募集到受伤组织中的成纤维细胞,从而使伤口愈合而不需要成纤维细胞移植。 在G-CSF施用后,成纤维细胞迁移到心肌梗塞病变中并防止心脏功能的降低,从而减轻心脏重塑。

    Clamper and in-channel-head operation device
    3.
    发明授权
    Clamper and in-channel-head operation device 有权
    钳位和通道头操作装置

    公开(公告)号:US09490037B2

    公开(公告)日:2016-11-08

    申请号:US13818524

    申请日:2011-07-28

    摘要: A clamper (23) includes a clamp mechanism (231) which inserts an insertion portion (2311a) into a tube member and clamps the tube member and a lifting and lowering mechanism (232) which lifts and lowers the clamp mechanism (231) in the insertion direction of the insertion portion (2311a). The clamp mechanism (231) includes a clamp body (2311) which has the insertion portion (2311a), a cotter (2312) which protrudes from the insertion portion (2311a) to come into friction-contact with the tube member and is movable in a reciprocating manner in the insertion direction of the insertion portion (2311a), a piston rod (2313) which presses the cotter (2312) so that the cotter protrudes from the insertion portion (2311a) when being pulled toward the opposite side to the insertion direction of the insertion portion (2311a), and a rod cylinder (2315) which is integrated with the clamp body (2311) and pulls the piston rod (2313).

    摘要翻译: 夹持器(23)包括夹持机构(231),该夹紧机构将插入部分(2311a)插入到管件中并夹紧管件,并且提升和降低夹紧机构(231)的升降机构 插入部(2311a)的插入方向。 夹紧机构231包括具有插入部2311a的夹持体2311,从该插入部2311a突出而与管构件摩擦接触的开口2312, 在插入部分(2311a)的插入方向上往复运动的方式,一个活塞杆(2313),当活塞杆(2313)被拉向相对于插入部分 插入部分(2311a)的方向,以及与夹紧体(2311)一体并拉动活塞杆(2313)的杆筒(2315)。

    WATER-CHAMBER WORKING APPARATUS
    4.
    发明申请
    WATER-CHAMBER WORKING APPARATUS 有权
    水箱工作装置

    公开(公告)号:US20120255289A1

    公开(公告)日:2012-10-11

    申请号:US13517180

    申请日:2011-01-19

    申请人: Jun Fujita

    发明人: Jun Fujita

    IPC分类号: F15B13/00

    摘要: A water-chamber working apparatus 1 according to the present invention includes a movable body that can move along a tube plate 12 of a steam generator 10, an extendable member 21 that extends and retracts in a direction in which a first coupling portion 21d approach each other and a direction in which these portions move away from each other, where the first coupling portion 21d is attached to a maintenance hatch 15 via a first joint 23a including two rotation axes intersecting with each other, and the second coupling portion 21e is attached to the movable body via a second joint 23b including two rotation axes intersecting with each other, which are different from the rotation axes of the first joint 23a.

    摘要翻译: 根据本发明的水室加工装置1包括可沿着蒸汽发生器10的管板12移动的可移动体,沿第一联接部分21d接近的方向延伸和缩回的可延伸构件21 另一方和这些部分彼此远离的方向,其中第一联接部分21d经由包括彼此相交的两个旋转轴线的第一接头23a附接到维护舱口15,并且第二联接部分21e附接到 可移动体经由包括与第一接头23a的旋转轴线不同的彼此相交的两个旋转轴线的第二接头23b。

    SHOT PEENING APPARATUS
    5.
    发明申请

    公开(公告)号:US20120227454A1

    公开(公告)日:2012-09-13

    申请号:US13512404

    申请日:2010-11-02

    申请人: Jun Fujita

    发明人: Jun Fujita

    IPC分类号: C21D7/06

    摘要: To correspond to a shape of a shot-peening worked portion and to prevent a situation where shot media scatter around the worked portion. To achieve this object, a shot peening apparatus for hitting shot media B against a welded part W and for applying a compressive stress to the welded part includes a kinetic-energy applying unit 26 that applies kinetic energy to the shot media B by an oscillator 26b, and a surrounding unit that surrounds both a worked portion U including the welded part W and surroundings of the oscillator 26b, and that confines the shot media B within the surrounded region while changing a state to correspond to a shape of the worked portion U.

    摘要翻译: 对应于喷丸加工部分的形状并防止喷丸介质在加工部分周围散落的情况。 为了实现这个目的,用于将冲击介质B撞击焊接部分W并向焊接部分施加压缩应力的喷丸硬化装置包括:动能施加单元26,其通过振荡器26b向喷射介质B施加动能 以及围绕包括焊接部分W和振荡器26b的周围的加工部分U的周围单元,并且将喷射介质B限制在被包围的区域内,同时改变状态以对应于加工部分U的形状。

    Device and method for joining ceramics structural body
    6.
    发明授权
    Device and method for joining ceramics structural body 失效
    陶瓷结构体连接装置及方法

    公开(公告)号:US07883599B2

    公开(公告)日:2011-02-08

    申请号:US11808232

    申请日:2007-06-07

    摘要: There is provided a device for bonding ceramic structural bodies. In the state in which a set of ceramic structural bodies provided with a bonding agent between bonding surfaces and provided with elastic sleeves disposed on a peripheral surface of the set of the structural bodies are placed in a tubular container with an elastic sheet disposed between the elastic sleeves and the tubular container, the device is able to charge a hydrostatic pressure medium between the tubular container and the elastic sheet to press and bond the structural bodies. By bonding the ceramic structural bodies with the device, it may provide accurate positioning of the bonding surfaces. It may also provide a uniform distance between bonded surfaces, and reduce the number of bonding operations, thereby affording an excellent working efficiency.

    摘要翻译: 提供了一种用于粘结陶瓷结构体的装置。 在一组陶瓷结构体在接合表面之间设置有粘合剂并且设置有设置在该组结构体的圆周表面上的弹性套筒的状态下,放置在管状容器中,弹性片设置在弹性片 袖子和管状容器,该装置能够对管状容器和弹性片之间的流体静压介质进行加压并结合结构体。 通过将陶瓷结构体与器件结合,可以提供接合表面的精确定位。 也可以在接合面之间提供均匀的距离,并且减少接合操作的数量,从而提供优异的工作效率。

    GANKYRIN
    7.
    发明申请
    GANKYRIN 失效
    甘金

    公开(公告)号:US20090163438A1

    公开(公告)日:2009-06-25

    申请号:US12372899

    申请日:2009-02-18

    申请人: Jun Fujita

    发明人: Jun Fujita

    IPC分类号: A61K31/7088 A61P35/00

    摘要: Gankyrin having the amino acid sequence as set forth in SEQ ID NO: 2, or modified gankyrin comprising an amino acid sequence modified by the deletion and/or addition of one or a plurality of amino acids and/or the substitution with other amino acids in the amino acid sequence of SEQ ID NO: 2 and retaining the biological activity of gankyrin, a gene encoding it, and a method of preparing said protein and uses thereof.

    摘要翻译: 具有SEQ ID NO:2所示的氨基酸序列的Gankyrin或包含通过一个或多个氨基酸的缺失和/或添加修饰的氨基酸序列和/或用其他氨基酸取代的氨基酸序列的修饰的gankyrin SEQ ID NO:2的氨基酸序列,并保持gankyrin的生物活性,编码它​​的基因,以及制备所述蛋白质的方法及其用途。

    Signal processing device, signal processing method, signal processing program, recording medium storing the program, speed detector and servomechanism
    8.
    发明授权
    Signal processing device, signal processing method, signal processing program, recording medium storing the program, speed detector and servomechanism 失效
    信号处理装置,信号处理方法,信号处理程序,存储程序的记录介质,速度检测器和伺服机构

    公开(公告)号:US07528565B2

    公开(公告)日:2009-05-05

    申请号:US11312529

    申请日:2005-12-21

    IPC分类号: G05B11/01

    CPC分类号: G05B19/416 G05B2219/41373

    摘要: A signal processing device processes a position information signal (A sinθ, A cosθ) output from a sensor in accordance with a driving position of a motor and detects a driving speed of the motor. The signal processing device includes a position information signal processor (410) that processes the position information signal and calculates driving speed information of the motor, and an internal position information generator (460) that reflects a latest driving speed information (ωn) calculated by the position information signal processor (410) and generates a latest presumed position of the motor as internal position information. The position information signal processor (410) calculates driving speed information (ωn) of the motor based on a difference between the position information signal (A sinθ, A cosθ) from the sensor and the internal position information (A sinθn, A cosθn) generated by the internal position information generator (460).

    摘要翻译: 信号处理装置根据电动机的驱动位置处理从传感器输出的位置信息信号(A sintheta,A costheta),并检测电动机的驱动速度。 信号处理装置包括处理位置信息信号并计算电动机的驱动速度信息的位置信息信号处理器(410),以及内部位置信息发生器(460),其反映由所述电动机计算出的最新行驶速度信息(ω) 位置信息信号处理器(410),并且产生作为内部位置信息的电动机的最新推测位置。 位置信息信号处理器(410)基于来自传感器的位置信息信号(A sintheta,A costheta)与产生的内部位置信息(A sinthetan,A costhetan)之间的差异来计算电动机的行驶速度信息(ω) 通过内部位置信息发生器(460)。

    Sealing material, method for sealing honeycomb structure and sealed honeycomb structure
    9.
    发明授权
    Sealing material, method for sealing honeycomb structure and sealed honeycomb structure 有权
    密封材料,蜂窝结构密封方法和密封蜂窝结构

    公开(公告)号:US07300487B2

    公开(公告)日:2007-11-27

    申请号:US10505612

    申请日:2003-02-05

    申请人: Jun Fujita

    发明人: Jun Fujita

    IPC分类号: C09K3/10 B01D39/20

    摘要: There is disclosed a sealing material for sealing a ceramic structure, the sealing material containing a ceramic component, an ordinary-temperature liquid component, and a suspending agent. In a method in which opening end portions of a large number of through channels 3 divided by partition walls 2 and extending in an axial direction in a honeycomb structure 1 including the through channels, the method comprises the steps of: sealing the opening end portions using the above-described sealing material. Sealed portions 10 are formed in the opening end portions of the through channels 3 by the sealing material. There are disclosed a sealing material, a sealing method for a honeycomb structure, and a sealed honeycomb structure in which less kinks are generated in the sealed portions, and a depth in each sealed portion fluctuates little.

    摘要翻译: 公开了一种用于密封陶瓷结构的密封材料,该密封材料含有陶瓷组分,常温液体组分和悬浮剂。 在通过分隔壁2分割并在包括贯通通道的蜂窝结构体1中沿轴向延伸的多个通道3的开口端部的方法中,该方法包括以下步骤:使用 上述密封材料。 密封部分10通过密封材料形成在通道3的开口端部中。 公开了一种密封材料,蜂窝状结构体的密封方法和密封蜂窝结构体,其密封部分产生较少的扭结,并且每个密封部分的深度几乎不发生波动。

    Method of connecting ceramics structure
    10.
    发明申请
    Method of connecting ceramics structure 有权
    连接陶瓷结构的方法

    公开(公告)号:US20060225833A1

    公开(公告)日:2006-10-12

    申请号:US10542848

    申请日:2004-03-25

    IPC分类号: B32B37/00

    摘要: A method of bonding at least a first ceramics structure (101) to a second ceramics structure (102), which includes the steps of applying a pressure to the first ceramics structure (101) and the second ceramics structure (102) in such a direction that these structures move close to each other with a bonding material layer (110) interposed between the first ceramics structure (101) and the second ceramics structure (102) (FIG. A), removing a bonding material (111a) extruded from the bonding material layer (110) to an end face of a stacked body including the first ceramics structure (101) and the second ceramics structure (102) by the application of the pressure thereto (FIG. B), drying a bonding material (111b) near the end face of the stacked body (120) after the extruded bonding material (111a) is removed (FIG. C), and drying the entire part of the stacked body (120).

    摘要翻译: 至少将第一陶瓷结构(101)接合到第二陶瓷结构(102)的方法,包括以下步骤:向第一陶瓷结构(101)和第二陶瓷结构(102)施加压力 这些结构通过介于第一陶瓷结构(101)和第二陶瓷结构(102)(A))之间的接合材料层(110)彼此靠近移动,从而从第一陶瓷结构(101)和第二陶瓷结构 通过施加压力将接合材料层(110)连接到包括第一陶瓷结构(101)和第二陶瓷结构(102)的层叠体的端面(图B),干燥接合材料(111b )在挤出的接合材料(111a)被去除之后靠近堆叠体(120)的端面(图C),并且干燥整个堆叠体(120)的部分。