公开(公告)号：US5141741A

公开(公告)日：1992-08-25

申请号：US444960

申请日：1989-12-04

申请人： Keiichiro Ishida ,  Yoshimi Sato ,  Makoto Egawa ,  Keiji Takeuchi

发明人： Keiichiro Ishida ,  Yoshimi Sato ,  Makoto Egawa ,  Keiji Takeuchi

IPC分类号： A61K8/49 ,  A61K8/60 ,  A61Q1/02 ,  A61Q17/04

CPC分类号： A61Q17/04 ,  A61K8/498 ,  A61K8/602 ,  A61Q1/02 ,  Y10S424/05 ,  Y10S514/844 ,  Y10S514/845 ,  Y10S514/846 ,  Y10S514/847

摘要： A novel anti-sunburn skin-care preparation, such as creams, foundations, milky lotions and the like, is proposed which contains, as the ultraviolet-absorbing and -shielding ingredient, a salt of ellagic acid with a polyvalent metal, e.g., calcium, barium and magnesium. The skin-care preparation is free from the problem of irritation and sensitization of human skin and exhibits excellent anti-sunburn effect with durability.

摘要翻译： 提出了一种抗紫外线护肤制剂，例如乳膏，地基，乳液等，其中含有作为紫外线吸收和遮蔽成分的鞣花酸与多价金属的盐，例如钙 ，钡和镁。 护肤品不含人皮肤刺激和敏化的问题，具有优异的抗晒伤效果和耐久性。

公开(公告)号：US06066312A

公开(公告)日：2000-05-23

申请号：US893648

申请日：1997-07-11

申请人： Makoto Egawa ,  Yukiko Marui

发明人： Makoto Egawa ,  Yukiko Marui

IPC分类号： A61K8/49 ,  A61K8/60 ,  A61K8/86 ,  A61Q19/02 ,  C07H3/04 ,  C07H17/04 ,  A61K7/48

CPC分类号： C07H3/04 ,  A61K8/498 ,  A61K8/60 ,  A61K8/86 ,  A61Q19/02 ,  Y10S514/844

摘要： A composition for external application having excellent percutaneous absorption property and skin-lightening and whitening effects, is disclosed, which composition comprises at least one particulate material selected from specific ellagic acid-based compound and an alkali metal salt of the ellagic acid-based compound, wherein the particulate material has an average particle diameter of not more than 50 .mu.m and contains particles having a particle diameter of not more than 70 .mu.m in an amount of not less than 70% by weight based on the weight of the particulate material.

摘要翻译： 公开了具有优异的经皮吸收性和皮肤亮白美白效果的外用组合物，该组合物含有选自鞣花酸类化合物的特定鞣花酸系化合物和碱金属盐中的至少一种微粒材料， 其中所述颗粒材料的平均粒径不大于50μm，并且包含粒径不大于70μm的颗粒，其量不小于基于颗粒材料的重量的70重量％。

公开(公告)号：US5017368A

公开(公告)日：1991-05-21

申请号：US472438

申请日：1990-01-31

申请人： Keikichi Sugiyama ,  Koji Takada ,  Akira Fukushima ,  Makoto Egawa

发明人： Keikichi Sugiyama ,  Koji Takada ,  Akira Fukushima ,  Makoto Egawa

IPC分类号： A61K8/00 ,  A61K8/34 ,  A61K8/36 ,  A61K8/49 ,  A61K8/64 ,  A61Q5/00 ,  A61Q5/10 ,  A61Q7/00

CPC分类号： A61K8/498 ,  A61K8/64 ,  A61Q5/10 ,  A61Q7/00

摘要： A composition for application to hair or scalp comprises (A) at least one compound selected from the group consisting of (i) forskolin and derivatives thereof and (ii) peptides having a basic skeletal structure represented by the following general formula (I):-P-Glu-His-Q-Arg-Trp-Gly-Lys- (I)(wherein P represents an L-norleucine or L-methionine residue; Q represents a D- or L-phenylalamine residue; and Glu, His, Arg, Trp, Gly and Lys are L-glutamic acid, L-histidine, L-arginine, L-tryptophan, glycine and L-lysine residues respectively); or the component A and (B) at least one compound selected from the group consisting of aliphatic acids, alcohols and derivatives thereof having an odd number of carbon atoms. The composition for hair or scalp exhibits excellent effect of preventing graying of the hair and restoring grayed hair to its natural color upon externally applied to the scalp and is highly safe as regards to the possibility of causing skin damage. Therefore, the composition can be widely used in various forms capable of being externally applied to the scalp.