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公开(公告)号：US07541350B2
公开(公告)日：2009-06-02
申请号：US10918779
申请日：2004-08-13
CPC分类号： A61K9/0078 , A61K9/0043 , A61K31/56 , A61K31/58 , A61K47/38
摘要： There is provided a pharmaceutical formulation comprising an aqueous suspension of particulate compound of formula (I) or a solvate thereof.
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公开(公告)号：US06858596B2
公开(公告)日：2005-02-22
申请号：US10067020
申请日：2002-02-04
IPC分类号： A61K9/10 , A61K9/00 , A61K31/56 , A61K31/568 , A61K31/57 , A61K31/58 , A61K47/02 , A61K47/18 , A61K47/34 , A61K47/36 , A61K47/38 , A61L9/04 , A61P5/44 , A61P11/02 , A61P29/00 , A61P37/08 , C07J3/00 , C07J17/00 , C07J53/00 , C07J71/00
CPC分类号： A61K9/0078 , A61K9/0043 , A61K31/56 , A61K31/58 , A61K47/38
摘要： There is provided a pharmaceutical formulation comprising an aqueous suspension of particulate compound of formula (I) or a solvate thereof.
摘要翻译： 提供了包含式（I）的颗粒化合物或其溶剂化物的水性悬浮液的药物制剂。
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![Pyrazolo[3,4-b]pyridine compound, and its use as a PDE4 inhibitor](/abs-image/US/2010/05/04/US07709497B2/abs.jpg.150x150.jpg)
3.发明授权公开(公告)号：US07709497B2
公开(公告)日：2010-05-04
申请号：US10598838
申请日：2005-03-15
申请人： Siegfried Benjamin Christensen, IV , Caroline Mary Cook , Christopher David Edlin , Martin Redpath Johnson , Paul Spencer Jones , Mika Kristian Lindvall , Amyn Pyarali Sayani , Naimisha Trivedi , Lionel Trottet
发明人： Siegfried Benjamin Christensen, IV , Caroline Mary Cook , Christopher David Edlin , Martin Redpath Johnson , Paul Spencer Jones , Mika Kristian Lindvall , Amyn Pyarali Sayani , Naimisha Trivedi , Lionel Trottet
IPC分类号： A61K31/44 , A01N43/42 , C07D471/02 , C07D491/02 , C07D498/02
CPC分类号： C07D471/04
摘要： The invention provides 4-{[1-(aminocarbonyl)-4-piperidinyl]amino}-N-[(3,4-dimethylphenyl)methyl]-1-ethyl-1H-pyrazolo[3,4-b]pyridine-5-carboxamide, which is the compound of formula (I): or a salt thereof.
摘要翻译： 本发明提供4 - {[1-（氨基羰基）-4-哌啶基]氨基} -N - [（3,4-二甲基苯基）甲基] -1-乙基-1H-吡唑并[3,4-b]吡啶-5 甲酰胺，其为式（I）的化合物或其盐。
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![Pyrazolo[3,4-B]Pyridine Compound, and Its Use as a Pde4 Inhibitor](/abs-image/US/2008/10/16/US20080255186A1/abs.jpg.150x150.jpg)
4.发明申请Pyrazolo[3,4-B]Pyridine Compound, and Its Use as a Pde4 Inhibitor 审中-公开吡唑并[3,4-B]吡啶化合物及其作为Pde4抑制剂的用途公开(公告)号：US20080255186A1
公开(公告)日：2008-10-16
申请号：US12067994
申请日：2006-09-29
IPC分类号： A61K31/437 , C07D471/04 , A61P17/00
CPC分类号： C07D471/04
摘要： The invention provides N-{[1,6-diethyl-4-(tetrahydro-2H-pyran-4-ylamino)-1H-pyrazolo[3,4-b]pyridin-5-yl]methyl}-3-methyl-5-isoxazolecarboxamide or a salt thereof, such as the compound or a pharmaceutically acceptable salt thereof. The invention also provides the use of the compound or salt as an inhibitor of phosphodiesterase type IV (PDE4.
摘要翻译： 本发明提供了N - {[1,6-二乙基-4-（四氢-2H-吡喃-4-基氨基）-1H-吡唑并[3,4-b]吡啶-5-基]甲基} -3-甲基 - 5-异恶唑甲酰胺或其盐，例如化合物或其药学上可接受的盐。 本发明还提供了化合物或盐作为IV型磷酸二酯酶抑制剂（PDE4）的用途。
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