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1.
公开(公告)号:US06463327B1
公开(公告)日:2002-10-08
申请号:US09533880
申请日:2000-03-22
申请人: Keith G. Lurie , Todd M. Zielinski , Wolfgang Voelckel , Robert Patterson , Nemer Samniah , Scott McKnite , Karl Lindner
发明人: Keith G. Lurie , Todd M. Zielinski , Wolfgang Voelckel , Robert Patterson , Nemer Samniah , Scott McKnite , Karl Lindner
IPC分类号: A61N136
CPC分类号: A61H31/00 , A61H31/005 , A61H31/006 , A61H31/007 , A61H2031/002 , A61H2201/165 , A61H2201/5007 , A61H2201/5043 , A61H2201/5048 , A61H2201/5061 , A61M16/0084 , A61M16/04 , A61M16/0434 , A61M16/06 , A61M16/0683 , A61M16/205 , A61M16/209 , A61M2016/0027 , A61M2230/08 , A61M2230/205 , A61M2230/50 , A61N1/0456 , A61N1/046 , A61N1/3601 , A61N1/36014 , A61N1/39 , A61N2/002
摘要: Provided are exemplary devices and methods for electrically stimulating the phrenic nerve. In one embodiment, electrodes are placed posterior and anterior in the region of the cervical vertebrae. Electrical current having a multi-phasic waveform is periodically applied to the electrodes to stimulate the phrenic nerve, thereby causing the diaphragm to contract.
摘要翻译: 提供用于电刺激膈神经的示例性装置和方法。 在一个实施例中,电极在颈椎的区域中的后部和前部放置。 周期性地向电极施加具有多相波形的电流以刺激膈神经,从而使隔膜收缩。
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2.
公开(公告)号:US06587726B2
公开(公告)日:2003-07-01
申请号:US10158528
申请日:2002-05-29
申请人: Keith G. Lurie , Todd M. Zielinski , Wolfgang Voelckel , Robert Patterson , Nemer Samniah , Scott McKnite , Karl Lindner
发明人: Keith G. Lurie , Todd M. Zielinski , Wolfgang Voelckel , Robert Patterson , Nemer Samniah , Scott McKnite , Karl Lindner
IPC分类号: A61N118
CPC分类号: A61H31/00 , A61H31/005 , A61H31/006 , A61H31/007 , A61H2031/002 , A61H2201/165 , A61H2201/5007 , A61H2201/5043 , A61H2201/5048 , A61H2201/5061 , A61M16/0084 , A61M16/04 , A61M16/0434 , A61M16/06 , A61M16/0683 , A61M16/205 , A61M16/209 , A61M2016/0027 , A61M2230/08 , A61M2230/205 , A61M2230/50 , A61N1/0456 , A61N1/046 , A61N1/3601 , A61N1/36014 , A61N1/39 , A61N2/002
摘要: The invention provides exemplary devices and methods electrically stimulating the phrenic nerve. In one embodiment, electrodes are placed posterior and anterior in the region of the cervical vertebrae. Electrical current having a multi-phasic waveform is periodically applied to the electrodes to stimulate the phrenic nerve, thereby causing the diaphragm to contract.
摘要翻译: 本发明提供了电刺激膈神经的示例性装置和方法。 在一个实施例中,电极在颈椎的区域中的后部和前部放置。 周期性地向电极施加具有多相波形的电流以刺激膈神经,从而使隔膜收缩。
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公开(公告)号:US06776156B2
公开(公告)日:2004-08-17
申请号:US09967029
申请日:2001-09-28
申请人: Keith G. Lurie , Wolfgang Voelckel
发明人: Keith G. Lurie , Wolfgang Voelckel
IPC分类号: A61M1600
CPC分类号: A61M16/208 , A61H31/00 , A61H2201/105 , A61M16/0825 , A61M16/107
摘要: A method for administering a drug to a patient comprises coupling a valve system to the patient's airway. The valve system is configured to prevent or impede respiratory gases from flowing into the lungs for at least some time such that the intrathoracic pressure is less than atmospheric pressure. A drug is introduced into the patient, and the intrathoracic pressure is lowered using the valve system to cause blood to flow into the thorax and thereby increasing vital organ perfusion to enhance the circulation of the drug.
摘要翻译: 向患者施用药物的方法包括将阀系统连接到患者的气道。 阀系统被配置为防止或阻止呼吸气体流入肺中至少一段时间,使得胸内压力小于大气压。 将药物引入患者体内,使用阀门系统降低胸内压力,使血液流入胸腔,从而增加重要的器官灌注,增强药物的循环。
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公开(公告)号:US06935336B2
公开(公告)日:2005-08-30
申请号:US10920678
申请日:2004-08-17
申请人: Keith G. Lurie , Wolfgang Voelckel
发明人: Keith G. Lurie , Wolfgang Voelckel
CPC分类号: A61M16/208 , A61H31/00 , A61H2201/105 , A61M16/0825 , A61M16/107
摘要: A method for administering a drug to a patient comprises coupling a valve system to the patient's airway. The valve system is configured to prevent or impede respiratory gases from flowing into the lungs for at least some time such that the intrathoracic pressure is less than atmospheric pressure. A drug is introduced into the patient, and the intrathoracic pressure is lowered using the valve system to cause blood to flow into the thorax and thereby increasing vital organ perfusion to enhance the circulation of the drug.
摘要翻译: 向患者施用药物的方法包括将阀系统连接到患者的气道。 阀系统被配置为防止或阻止呼吸气体流入肺中至少一段时间,使得胸内压力小于大气压。 将药物引入患者体内,使用阀门系统降低胸内压力,使血液流入胸腔,从而增加重要的器官灌注,增强药物的循环。
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公开(公告)号:US06425393B1
公开(公告)日:2002-07-30
申请号:US09386868
申请日:1999-08-31
IPC分类号: A62B700
CPC分类号: A61M16/04 , A61H31/00 , A61H31/005 , A61H31/006 , A61H31/007 , A61H2031/001 , A61H2201/1238 , A61M16/0078 , A61M16/0084 , A61M16/06 , A61M16/1065 , A61M16/107 , A61M16/20 , A61M16/208 , A61M16/209
摘要: The invention provides exemplary methods and valves used to alter a person's breathing. In one method, an exit valve is interfaced with a person's airway. The exit valve is configured such that respiratory gases are prevented from exiting the person's lungs when the exit valve is closed and are permitted to exit the person's lungs when the exit valve is opened. The exit valve is configured to open when a valve actuating pressure is met or exceeded. In a further step, the valve actuating pressure is varied over time.
摘要翻译: 本发明提供用于改变人的呼吸的示例性方法和阀。 在一种方法中,出口阀与人的气道接口。 出口阀构造成使得当出口阀关闭时防止呼吸气体离开人的肺,并且当排出阀打开时允许其离开人的肺。 出口阀构造成当阀门执行压力达到或超过时打开。 在另一步骤中,阀致动压力随时间变化。
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公开(公告)号:US20050016541A1
公开(公告)日:2005-01-27
申请号:US10920678
申请日:2004-08-17
申请人: Keith Lurie , Wolfgang Voelckel
发明人: Keith Lurie , Wolfgang Voelckel
CPC分类号: A61M16/208 , A61H31/00 , A61H2201/105 , A61M16/0825 , A61M16/107
摘要: A method for administering a drug to a patient comprises coupling a valve system to the patient's airway. The valve system is configured to prevent or impede respiratory gases from flowing into the lungs for at least some time such that the intrathoracic pressure is less than atmospheric pressure. A drug is introduced into the patient, and the intrathoracic pressure is lowered using the valve system to cause blood to flow into the thorax and thereby increasing vital organ perfusion to enhance the circulation of the drug.
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