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    Laser nephelometric system
    2.
    发明授权
    Laser nephelometric system 失效
    激光浊度计系统

    公开(公告)号：US4408880A

    公开(公告)日：1983-10-11

    申请号：US304578

    申请日：1981-09-22

    申请人： Yashuhiro Tsuji ,  Kiyoshige Wakabayashi ,  Mitsuo Watanabe

    发明人： Yashuhiro Tsuji ,  Kiyoshige Wakabayashi ,  Mitsuo Watanabe

    IPC分类号： G01N15/02 ,  G01N21/49 ,  G01N21/00

    CPC分类号： G01N21/49 ,  G01N2015/0222

    摘要： A laser nephelometric system measures the concentration of various substances in a solution particularly in blood or serum. The system receives a number of data elements each indicative of the intensity of light scattered from the solution at its sampling time. These data elements are processed in accordance with a statistical analysis. Based upon the fact that the relative variation of the scattered light intensity increases as the scattered light decreases, a first screening of data elements is performed so that the band of selection for data elements accords with the above fact. Further a second screening of data elements is performed in order to reduce the effect of the unnecessary light resulting from the other reflecting objects, such as dust, air bubbles and other substances. The average of the screened data elements provides an accurate value of the intensity of scattered light due to the substances to be measured, i.e. measurand.

    摘要翻译： 激光比浊法测量溶液中各种物质的浓度，特别是血液或血清中的浓度。 系统接收多个数据元素，每个数据元素指示在其采样时间从解决方案散射的光的强度。 这些数据元素根据统计分析进行处理。 基于散射光强度的相对变化随着散射光的减小而增加的事实，执行数据元素的第一次筛选，使得数据元素的选择频带符合上述事实。 此外，进行数据元素的第二次筛选以便减少由诸如灰尘，气泡和其它物质的其它反射物体引起的不必要的光的影响。 筛选的数据元素的平均值提供了由于待测量的物质即被测量的散射光的强度的准确值。

    Light scattering immunoassay involving particles with selective frequency band apparatus
    3.
    发明授权
    Light scattering immunoassay involving particles with selective frequency band apparatus 失效
    涉及具有选择性频带装置的颗粒的光散射免疫测定

    公开(公告)号：US4446239A

    公开(公告)日：1984-05-01

    申请号：US368610

    申请日：1982-04-15

    申请人： Yasuhiro Tsuji ,  Kiyoshige Wakabayashi

    发明人： Yasuhiro Tsuji ,  Kiyoshige Wakabayashi

    IPC分类号： G01N21/49 ,  G01N15/14 ,  G01N21/47 ,  G01N33/543 ,  G01N33/54

    CPC分类号： G01N33/54313 ,  G01N21/47 ,  Y10S436/805 ,  Y10S436/807 ,  Y10S436/817

    摘要： A technique for measuring the degree of an antigen-antibody reaction by preparing a suspension of insoluble microscopic carrier particles of at least one type carrying an antigen, an antibody or a hapten, forming an agglutination promoting or inhibiting reaction system among the insoluble carrier particles based on an antigen-antibody reaction using the suspension and one or more antigen, antibody or hapten, irradiating the solution of the reaction system with laser light and detecting the light scattered from the reaction system at one or more specific angles, detecting a signal indicative of one or more specific frequency bands from the resulting scatter spectrum, and thenceforth calculating the quantity of antigen, antibody or hapten in a specimen on the basis of the detected signal. The intensity spectrum output of filter 11 for frequency band selection is in the form of a square root and is converted into the original intensity spectrum by means of a squaring circuit 12. The output of the squaring circuit is recorded by a recorder 10.

    摘要翻译： 一种用于通过制备至少一种携带抗原，抗体或半抗原的不溶性微观载体颗粒的悬浮液来测量抗原 - 抗体反应程度的技术，其形成不溶性载体颗粒之间的凝集促进或抑制反应系统 在使用悬浮液和一种或多种抗原，抗体或半抗原的抗原 - 抗体反应上，用激光照射反应体系的溶液，并以一个或多个特定角度检测从反应体系散射的光，检测指示 来自所得散射光谱的一个或多个特定频带，然后基于检测到的信号计算样品中的抗原，抗体或半抗原的量。 用于频带选择的滤波器11的强度谱输出是平方根的形式，并通过平方电路12转换成原强度谱。平方电路的输出由记录器10记录。

    Liquid uptake and discharge apparatus
    5.
    发明授权
    Liquid uptake and discharge apparatus 失效
    液体吸收和排出装置

    公开(公告)号：US4429583A

    公开(公告)日：1984-02-07

    申请号：US362161

    申请日：1982-03-26

    申请人： Mitsuo Watanabe ,  Shigeyuki Kimura ,  Hideki Konishi ,  Yasuhiro Tsuji ,  Kiyoshige Wakabayashi

    发明人： Mitsuo Watanabe ,  Shigeyuki Kimura ,  Hideki Konishi ,  Yasuhiro Tsuji ,  Kiyoshige Wakabayashi

    IPC分类号： G01N33/48 ,  B01L3/02 ,  G01N35/10 ,  G01F11/06

    CPC分类号： B01L3/0227 ,  B01L3/0206

    摘要： An apparatus for taking up and discharging liquid has at least one piston cylinder which responds to a command by taking up or discharging liquid, the arrangement being such that the number of liquid uptake operations is preset, with the piston cylinder being instructed to perform the discharge operation when the number of uptake operations actually performed is detected to exceed said preset number. A plurality of different liquid specimens can be mixed, and the mixture diluted when so desired, through a simple operation which assures great accuracy.

    摘要翻译： 用于吸收和排出液体的装置具有至少一个活塞缸，其通过吸取或排出液体来响应命令，该排列使得预先设定液体摄取操作的数量，同时指示活塞气缸进行排放 当检测到实际执行的摄取操作的数量超过所述预设数量时的操作。 可以混合多种不同的液体样品，并且当需要时通过简单的操作稀释混合物，这确保了高精度。