公开(公告)号：US5300107A

公开(公告)日：1994-04-05

申请号：US964737

申请日：1992-10-22

申请人： Kenneth B. Stokes ,  Keith J. Proctor ,  Tommy D. Bennett ,  Rick D. McVenes

发明人： Kenneth B. Stokes ,  Keith J. Proctor ,  Tommy D. Bennett ,  Rick D. McVenes

IPC分类号： A61N1/05 ,  A61N1/362

CPC分类号： A61N1/057

摘要： A myocardial pacing lead includes two sets of at least two tines placed to oppose each other. The lead is pressed against the epicardium and is rotated until a rough porous tip abrades the epicardium and allows the tip and the first row of tines to penetrate the myocardium. Excessive penetration and lead migration is prevented by the second row of tines which is mounted backward and just proximal from the first row of tines. The first row of tines anchor on the inside surface of the epicardium which prevents dislodgment. Dacron pads on the second row of tines assures chronic fixation by adhering to the outer surface of the patient's epicardium.

摘要翻译： 心肌起搏引线包括两组至少两根相对放置的齿。 将引线压向心外膜并旋转直到粗糙的多孔尖端磨损心外膜，并允许尖端和第一排刺入心肌。 通过第二排尖齿被安装在第一排尖端的后方并刚好靠近的第二排齿可以防止过度的穿透和牵伸移动。 第一排尖齿锚定在心外膜的内表面上，防止脱落。 第二排尖齿上的涤纶垫片通过粘附在患者的心外膜的外表面上来确保慢性固定。

公开(公告)号：US5443492A

公开(公告)日：1995-08-22

申请号：US189565

申请日：1994-02-02

申请人： Kenneth B. Stokes ,  Keith J. Proctor ,  Rick D. McVenes

发明人： Kenneth B. Stokes ,  Keith J. Proctor ,  Rick D. McVenes

IPC分类号： A61N1/05 ,  A61N1/04

CPC分类号： A61N1/0568 ,  A61N1/0573 ,  A61N2001/0578

摘要： An implantable lead for establishing electrical contact between a medical device and body tissue, in which an active fixation mechanism secures the lead in place while allowing a distal electrode on the lead to mechanically "float" with respect to the body tissue. In one embodiment, the active fixation mechanism comprises a curved hook disposed on the lead at a point spaced proximally back from the distal end of the lead. The curved hook defines a helix around at least a portion of the lead's circumference. A hollow introducer needle is slidably disposed on the lead. The hollow needle provided with a longitudinal slit in a distal section of is length, such that the distal section of the needle can be advanced over the distal end of the lead, past the fixation hook, which is received in the longitudinal slit. With the needle slid over the distal end of the lead, the needle is stabbed tangentially into an implant site, bringing the fixation hook proximal to the surface of the body tissue. Then, the needle is twisted (bringing about a twisting of the lead), causing the curved fixation hook to pierce and engage the body tissue, securing the lead in place. Then the needle is withdrawn from the body tissue and removed from the lead. In an alternative embodiment, the lead can be placed by an endocardial approach using a flexible cannula with a longitudinally slotted tip.

摘要翻译： 一种用于在医疗装置和身体组织之间建立电接触的可植入引线，其中主动固定机构将引线固定在适当位置，同时允许引线上的远端电极相对于身体组织机械地“浮动”。 在一个实施例中，主动固定机构包括设置在引线上的远离引导件远端的近距离间隔的点的弯曲钩。 弯曲的钩子围绕引线的周边的至少一部分限定螺旋。 中空导引针可滑动地设置在引线上。 中空针在远端部分设置有长度方向的狭缝，使得针的远端部分能够超过引线的远端延伸穿过容纳在纵向狭缝中的固定钩。 当针滑过导线的远端时，针被切向地刺入植入部位，使固定钩靠近身体组织的表面。 然后，针头扭转（导致引线扭转），导致弯曲的固定钩刺穿并接合身体组织，将导线固定到位。 然后将针从身体组织中取出并从铅中取出。 在替代实施例中，引线可以通过使用具有纵向开口尖端的柔性套管的心内膜方式放置。

公开(公告)号：US5489294A

公开(公告)日：1996-02-06

申请号：US189825

申请日：1994-02-01

申请人： Rick D. McVenes ,  Kenneth B. Stokes ,  Peter J. Pohndorf ,  Keith J. Proctor

发明人： Rick D. McVenes ,  Kenneth B. Stokes ,  Peter J. Pohndorf ,  Keith J. Proctor

IPC分类号： A61N1/05

CPC分类号： A61N1/0587

摘要： A chronic myocardial pacing lead for the delivery of stimulation energy to and the sensing of electrical signals from the myocardium of a human heart. In one embodiment the lead is bipolar, having a sleeve electrode implanted into the myocardium and a pad electrode positioned on the epicardium. The lead includes a drug for delivery through the sleeve electrode to the myocardium. The disclosed lead is highly flexible to minimize tissue reaction, this permits the lead to offer relatively low pacing thresholds, high impedance, and excellent sensing in a configuration which is relatively easy to implant.

摘要翻译： 慢性心肌起搏导致刺激能量的传递和对来自人心脏心肌的电信号的感测。 在一个实施例中，引线是双极的，其具有植入心肌的套管电极和位于心外膜上的焊盘电极。 引线包括用于通过套筒电极递送至心肌的药物。 所公开的引线是高度灵活的以最小化组织反应，这允许导线在相对容易植入的构造中提供相对较低的起搏阈值，高阻抗和优异的感测。

公开(公告)号：US5330525A

公开(公告)日：1994-07-19

申请号：US55128

申请日：1993-04-29

申请人： Keith J. Proctor

发明人： Keith J. Proctor

IPC分类号： A61N1/05

CPC分类号： A61N1/0587

摘要： An epicardial lead having an electrode extending from the bottom thereof in combination with an anchoring system adapted to secure the lead to the heart without the use of complex procedures or tools. In a preferred embodiment the epicardial lead comprises an electrode body having two oppositely disposed arms, each arm fixed for rotation, each arm having an arcuate anchor mounted to the bottom surface, each arcuate anchor having as the center of the arcuate shape the axis of rotation of the respective arm. Rotating the arms causes each arcuate anchor to move in a circular fashion such that when each arm is moved from an open position to a closed position the respective anchor is moved to engage and move through the cardiac tissue and thereby secure the lead to the heart.

摘要翻译： 一种心外膜引线，其具有从其底部延伸的电极以及适于将引线固定到心脏而不使用复杂程序或工具的锚定系统。 在优选实施例中，心外膜引线包括具有两个相对布置的臂的电极体，每个臂固定用于旋转，每个臂具有安装到底表面的弓形锚固件，每个弓形锚固件具有作为弧形形状的中心的旋转轴线 的相应臂。 旋转臂使得每个弓形锚固件以圆形方式移动，使得当每个臂从打开位置移动到关闭位置时，相应的锚移动以接合并移动穿过心脏组织，从而将引线固定到心脏。

公开(公告)号：US5047208A

公开(公告)日：1991-09-10

申请号：US314615

申请日：1989-02-23

申请人： Jeffrey A. Schweitzer ,  Keith J. Proctor

发明人： Jeffrey A. Schweitzer ,  Keith J. Proctor

IPC分类号： A61B5/00 ,  G01N21/77 ,  G01N21/80 ,  G01N33/84

CPC分类号： A61B5/145 ,  A61B5/14539 ,  G01N21/7703 ,  G01N33/84 ,  G01N21/80 ,  Y10T436/204998

摘要： Colorimetric, fiber optic sensors for measuring pH, PCO.sub.2 and/or other chemical parameters of the blood. The sensors are fabricated using a single optical fiber, which is provided with a chamber at its distal end containing a pH sensitive dye. Located distal to the chamber is a white reflective surface located within 0.04" from the end of the optical fiber, which enhances the performance of the sensor.

摘要翻译： 用于测量血液pH，PCO2和/或其他化学参数的比色光纤传感器。 传感器使用单个光纤制造，该光纤在其远端设置有包含pH敏感染料的腔室。 位于腔室的远侧是位于光纤末端0.04“内的白色反射表面，这增强了传感器的性能。

公开(公告)号：US4538623A

公开(公告)日：1985-09-03

申请号：US597953

申请日：1984-04-09

申请人： Keith J. Proctor ,  John D. Doring

发明人： Keith J. Proctor ,  John D. Doring

IPC分类号： A61N1/05 ,  A61N1/04

CPC分类号： A61N1/056

摘要： A threaded pacing electrode assembly for use in implantable electrical leads. The electrode is provided with an exposed portion adapted to make electrical contact with body tissue and with a cylindrical portion proximal to the exposed portion provided with a helical screw thread. A conductor coil which has an inner diameter smaller than the outer diameter of the cylindrical portion is mounted to the exterior of the cylindrical portion, coiled within the screw thread. A transparent insulating sleeve covers the cylindrical portion, is frictionally retained by the thread, and assists in maintaining the conductor coils in contact with the cylindrical portion.

摘要翻译： 用于可植入电引线的螺纹起搏电极组件。 电极设置有适于与身体组织电接触的暴露部分，以及靠近设置有螺旋螺纹的暴露部分的圆柱形部分。 具有小于圆筒部外径的内径的导体线圈安装在圆筒部的外部，螺旋在螺纹内。 透明绝缘套管覆盖圆柱形部分，被螺纹摩擦保持，并有助于保持导体线圈与圆柱形部分接触。