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    Intrapericardial lead
    1.
    发明授权
    Intrapericardial lead 有权
    心包积液

    公开(公告)号：US07899555B2

    公开(公告)日：2011-03-01

    申请号：US11691335

    申请日：2007-03-26

    申请人： Kevin L. Morgan ,  Steven R. Conger ,  Anna Barlow ,  Stuart Rosenberg ,  Wenbo Hou ,  Michael Yang ,  Sheldon Williams

    发明人： Kevin L. Morgan ,  Steven R. Conger ,  Anna Barlow ,  Stuart Rosenberg ,  Wenbo Hou ,  Michael Yang ,  Sheldon Williams

    IPC分类号： A61N1/05

    CPC分类号： A61N1/059 ,  A61N1/057 ,  A61N1/0587 ,  A61N2001/058

    摘要： The intrapericardial lead includes a lead body having a proximal portion and a flexible, pre-curved distal end portion. The distal end portion carries at least one electrode assembly containing an electrode adapted to engage pericardial tissue. The distal end portion further carries a pre-curved flexible wire member having ends attached to spaced apart points along the distal end portion of the lead body, the flexible wire member having a normally expanded state wherein an intermediate portion of the wire member is spaced apart from the distal end portion, and a generally straightened state wherein the wire member and the distal end portion are disposed in a more parallel, adjacent relationship so as to present a small frontal area to facilitate delivery into the pericardial space. The wire member re-expands to its normal state after delivery into the percaridal space to anchor the distal end portion of the lead body relative to the pericardial tissue.

    摘要翻译： 心包内引线包括具有近端部分和柔性的预弯曲远端部分的引线体。 远端部分携带至少一个电极组件，其包含适于接合心包组织的电极。 远端部分还承载预弯曲的柔性线构件，其具有沿着引线本体的远端部附接到间隔开的点的端部，柔性线构件具有正常膨胀状态，其中线构件的中间部分间隔开 以及大致直线状态，其中所述线构件和所述远端部分布置成更平行的相邻关系，以便呈现小的前部区域以便于输送到心包空间中。 导线部件在输送到大面积空间之后，再膨胀至其正常状态，以相对于心包组织锚固引线主体的远端部分。

    INTRAPERICARDIAL LEAD
    2.
    发明申请
    INTRAPERICARDIAL LEAD 有权
    国内领先

    公开(公告)号：US20070239244A1

    公开(公告)日：2007-10-11

    申请号：US11691335

    申请日：2007-03-26

    申请人： Kevin L. Morgan ,  Steven R. Conger ,  Anna Barlow ,  Stuart Rosenberg ,  Wenbo Hou ,  Michael Yang ,  Sheldon Williams

    发明人： Kevin L. Morgan ,  Steven R. Conger ,  Anna Barlow ,  Stuart Rosenberg ,  Wenbo Hou ,  Michael Yang ,  Sheldon Williams

    IPC分类号： A61N1/05

    CPC分类号： A61N1/059 ,  A61N1/057 ,  A61N1/0587 ,  A61N2001/058

    摘要： The intrapericardial lead includes a lead body having a proximal portion and a flexible, pre-curved distal end portion. The distal end portion carries at least one electrode assembly containing an electrode adapted to engage pericardial tissue. The distal end portion further carries a pre-curved flexible wire member having ends attached to spaced apart points along the distal end portion of the lead body, the flexible wire member having a normally expanded state wherein an intermediate portion of the wire member is spaced apart from the distal end portion, and a generally straightened state wherein the wire member and the distal end portion are disposed in a more parallel, adjacent relationship so as to present a small frontal area to facilitate delivery into the pericardial space. The wire member re-expands to its normal state after delivery into the percaridal space to anchor the distal end portion of the lead body relative to the pericardial tissue.

    摘要翻译： 心包内引线包括具有近端部分和柔性的预弯曲远端部分的引线体。 远端部分携带至少一个电极组件，其包含适于接合心包组织的电极。 远端部分还承载预弯曲的柔性线构件，其具有沿着引线本体的远端部附接到间隔开的点的端部，柔性线构件具有正常膨胀状态，其中线构件的中间部分间隔开 以及大致直线状态，其中所述线构件和所述远端部分布置成更平行的相邻关系，以便呈现小的前部区域以便于输送到心包空间中。 导线部件在输送到大面积空间之后，再膨胀至其正常状态，以相对于心包组织锚固引线主体的远端部分。

    INTRAPERICARDIAL LEAD
    3.
    发明申请
    INTRAPERICARDIAL LEAD 有权
    国内领先

    公开(公告)号：US20110106233A1

    公开(公告)日：2011-05-05

    申请号：US13005448

    申请日：2011-01-12

    申请人： Kevin L. Morgan ,  Steven R. Conger ,  Anna Barlow ,  Stuart Rosenberg ,  Wenbo Hou ,  Michael Yang ,  Sheldon Williams

    发明人： Kevin L. Morgan ,  Steven R. Conger ,  Anna Barlow ,  Stuart Rosenberg ,  Wenbo Hou ,  Michael Yang ,  Sheldon Williams

    IPC分类号： A61N1/05

    CPC分类号： A61N1/059 ,  A61N1/057 ,  A61N1/0587 ,  A61N2001/058

    摘要： The intrapericardial lead includes a lead body having a proximal portion and a flexible, pre-curved distal end portion. The distal end portion carries at least one electrode assembly containing an electrode adapted to engage pericardial tissue. The distal end portion further carries a pre-curved flexible wire member having ends attached to spaced apart points along the distal end portion of the lead body, the flexible wire member having a normally expanded state wherein an intermediate portion of the wire member is spaced apart from the distal end portion, and a generally straightened state wherein the wire member and the distal end portion are disposed in a more parallel, adjacent relationship so as to present a small frontal area to facilitate delivery into the pericardial space. The wire member re-expands to its normal state after delivery into the pericardial space to anchor the distal end portion of the lead body relative to the pericardial tissue.

    摘要翻译： 心包内引线包括具有近端部分和柔性的预弯曲远端部分的引线体。 远端部分携带至少一个电极组件，其包含适于接合心包组织的电极。 远端部分还承载预弯曲的柔性线构件，其具有沿着引线本体的远端部附接到间隔开的点的端部，柔性线构件具有正常膨胀状态，其中线构件的中间部分间隔开 以及大致直线状态，其中所述线构件和所述远端部分布置成更平行的相邻关系，以便呈现小的前部区域以便于输送到心包空间中。 导线部件在输送到心包空间之后再膨胀至正常状态，以相对于心包组织锚固引线主体的远端部分。

    Intrapericardial lead with precurved distal end portion
    4.
    发明授权
    Intrapericardial lead with precurved distal end portion 有权
    具有前端远端部分的心包内引线

    公开(公告)号：US08406902B2

    公开(公告)日：2013-03-26

    申请号：US13005448

    申请日：2011-01-12

    申请人： Kevin L. Morgan ,  Steven R. Conger ,  Anna Barlow ,  Stuart Rosenberg ,  Wenbo Hou ,  Michael Yang ,  Sheldon Williams

    发明人： Kevin L. Morgan ,  Steven R. Conger ,  Anna Barlow ,  Stuart Rosenberg ,  Wenbo Hou ,  Michael Yang ,  Sheldon Williams

    IPC分类号： A61N1/05

    CPC分类号： A61N1/059 ,  A61N1/057 ,  A61N1/0587 ,  A61N2001/058

    摘要： The intrapericardial lead includes a lead body having a proximal portion and a flexible, pre-curved distal end portion. The distal end portion carries at least one electrode assembly containing an electrode adapted to engage pericardial tissue. The distal end portion further carries a pre-curved flexible wire member having ends attached to spaced apart points along the distal end portion of the lead body, the flexible wire member having a normally expanded state wherein an intermediate portion of the wire member is spaced apart from the distal end portion, and a generally straightened state wherein the wire member and the distal end portion are disposed in a more parallel, adjacent relationship so as to present a small frontal area to facilitate delivery into the pericardial space. The wire member re-expands to its normal state after delivery into the pericardial space to anchor the distal end portion of the lead body relative to the pericardial tissue.

    摘要翻译： 心包内引线包括具有近端部分和柔性的预弯曲的远端部分的引线体。 远端部分携带至少一个电极组件，其包含适于接合心包组织的电极。 远端部分还承载预弯曲的柔性线构件，其具有沿着引线本体的远端部附接到间隔开的点的端部，柔性线构件具有正常膨胀状态，其中线构件的中间部分间隔开 以及大致直线状态，其中所述线构件和所述远端部分布置成更平行的相邻关系，以便呈现小的前部区域以便于输送到心包空间中。 导线部件在输送到心包空间之后再膨胀至正常状态，以相对于心包组织锚固引线主体的远端部分。

    Epicardial lead
    6.
    发明授权
    Epicardial lead 有权
    心外膜导联

    公开(公告)号：US07949411B1

    公开(公告)日：2011-05-24

    申请号：US11626132

    申请日：2007-01-23

    申请人： Michael Yang ,  Sheldon Williams ,  Wenbo Hou ,  Kevin L. Morgan ,  Xiaoyi Min

    发明人： Michael Yang ,  Sheldon Williams ,  Wenbo Hou ,  Kevin L. Morgan ,  Xiaoyi Min

    IPC分类号： A61N1/05

    CPC分类号： A61N1/0563 ,  A61N1/057

    摘要： Embodiments include electrical leads and methods of using electrical leads that may be used for delivering both cardioversion/defibrillation signals and pacing signals and sensing to target tissue. Some of these embodiments may also be used to sense and transmit electrical signals from target tissue. Some electrical lead embodiments are configured to be delivered into a patient's intrapericardial space by non-invasive methods.

    摘要翻译： 实施例包括电引线和使用电引线的方法，其可以用于将心律转复/除颤信号和起搏信号以及感测传送到目标组织。 这些实施例中的一些也可以用于感测和传输来自目标组织的电信号。 一些电引线实施例被配置为通过非侵入性方法递送到患者的心包内空间。

    Methods and systems to monitor and identify transient ischemia
    7.
    发明授权
    Methods and systems to monitor and identify transient ischemia 有权
    监测和鉴别短暂性脑缺血的方法和系统

    公开(公告)号：US08447389B2

    公开(公告)日：2013-05-21

    申请号：US12861573

    申请日：2010-08-23

    申请人： Steve Koh ,  Michael Yang ,  Ryan Rooke ,  Stuart Rosenberg ,  Wenbo Hou

    发明人： Steve Koh ,  Michael Yang ,  Ryan Rooke ,  Stuart Rosenberg ,  Wenbo Hou

    IPC分类号： A61B5/0452

    CPC分类号： A61B5/0422 ,  A61B5/686 ,  A61B5/7282 ,  A61B2576/023 ,  A61N1/365 ,  A61N1/3702

    摘要： A system and method are provided for monitoring ischemic development. The system and method identify a non-physiologic event and obtain cardiac signals along multiple sensing vectors, wherein at least a portion of the sensing vectors extend to or from electrodes located proximate to the left ventricle. The system and method monitor a segment of interest in the cardiac signals obtained along the multiple sensing vectors to identify deviations in the segment of interest from a baseline. The system and method record at least one of timing or segment shift information associated with the deviations in the segments of interest; and identify at least one of size, direction of development or rate of progression of an ischemia region based on the at least one of timing or segment shift information.

    摘要翻译： 提供了一种用于监测缺血发育的系统和方法。 系统和方法识别非生理事件并且沿着多个感测向量获得心脏信号，其中至少一部分感测向量延伸到位于靠近左心室的电极。 系统和方法监测沿着多个感测向量获得的心脏信号中的感兴趣区段，以识别感兴趣区段中的偏离基线。 系统和方法记录与感兴趣的部分中的偏差相关联的定时或分段移位信息中的至少一个; 并且基于定时或段位移信息中的至少一个来识别缺血区域的大小，发育方向或进展速度中的至少一个。

    Electrode and lead stability indexes and stability maps based on localization system data
    8.
    发明授权
    Electrode and lead stability indexes and stability maps based on localization system data 有权
    基于定位系统数据的电极和铅稳定性指标和稳定性图

    公开(公告)号：US08401645B2

    公开(公告)日：2013-03-19

    申请号：US12562003

    申请日：2009-09-17

    申请人： Stuart Rosenberg ,  Thao Thu Nguyen ,  Kyungmoo Ryu ,  Kjell Norén ,  Allen Keel ,  Wenbo Hou ,  Michael Yang

    发明人： Stuart Rosenberg ,  Thao Thu Nguyen ,  Kyungmoo Ryu ,  Kjell Norén ,  Allen Keel ,  Wenbo Hou ,  Michael Yang

    IPC分类号： A61N1/00 ,  A61B5/04

    CPC分类号： A61N1/3702 ,  A61B5/042 ,  A61B5/0424 ,  A61B2560/0276 ,  A61N1/368 ,  A61N1/371

    摘要： A method includes selecting an electrode located in a patient; acquiring position information with respect to time for the electrode where the acquiring uses the electrode for repeatedly measuring electrical potentials in an electrical localization field established in the patient; calculating a stability metric for the electrode based on the acquired position information with respect to time; and deciding if the selected electrode, as located in the patient, has a stable location for sensing biological electrical activity, for delivering electrical energy or for sensing biological electrical activity and delivering electrical energy. Position information may be acquired during one or both of intrinsic or paced activation of a heart and respective stability indexes calculated for each activation type.

    摘要翻译： 一种方法包括选择位于患者体内的电极; 获取相对于所述电极的时间的位置信息，其中所述电极在所述患者中建立的电定位场中使用所述电极重复测量电位; 基于获取的相对于时间的位置信息计算电极的稳定性度量; 并且确定位于患者体内的所选择的电极是否具有用于感测生物电活动的稳定位置，用于传递电能或用于感测生物电活动和递送电能。 位置信息可以在心脏的固有或起搏激活和对于每种激活类型计算的各个稳定性指标的一个或两个期间获取。

    METHODS AND SYSTEMS TO MONITOR AND IDENTIFY TRANSIENT ISCHEMIA
    10.
    发明申请
    METHODS AND SYSTEMS TO MONITOR AND IDENTIFY TRANSIENT ISCHEMIA 有权
    监测和识别过渡期ISCHEMIA的方法和系统

    公开(公告)号：US20120046564A1

    公开(公告)日：2012-02-23

    申请号：US12861573

    申请日：2010-08-23

    申请人： Steve Koh ,  Michael Yang ,  Ryan Rooke ,  Stuart Rosenberg ,  Wenbo Hou

    发明人： Steve Koh ,  Michael Yang ,  Ryan Rooke ,  Stuart Rosenberg ,  Wenbo Hou

    IPC分类号： A61B5/0402

    CPC分类号： A61B5/0422 ,  A61B5/686 ,  A61B5/7282 ,  A61B2576/023 ,  A61N1/365 ,  A61N1/3702

    摘要： A system and method are provided for monitoring ischemic development. The system and method identify a non-physiologic event and obtain cardiac signals along multiple sensing vectors, wherein at least a portion of the sensing vectors extend to or from electrodes located proximate to the left ventricle. The system and method monitor a segment of interest in the cardiac signals obtained along the multiple sensing vectors to identify deviations in the segment of interest from a baseline. The system and method record at least one of timing or segment shift information associated with the deviations in the segments of interest; and identify at least one of size, direction of development or rate of progression of an ischemia region based on the at least one of timing or segment shift information.

    摘要翻译： 提供了一种用于监测缺血发育的系统和方法。 系统和方法识别非生理事件并且沿着多个感测向量获得心脏信号，其中至少一部分感测向量延伸到位于靠近左心室的电极。 系统和方法监测沿着多个感测向量获得的心脏信号中的感兴趣区段，以识别感兴趣区段中的偏离基线。 系统和方法记录与感兴趣的部分中的偏差相关联的定时或分段移位信息中的至少一个; 并且基于定时或段位移信息中的至少一个来识别缺血区域的大小，发育方向或进展速度中的至少一个。