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公开(公告)号：US20060261005A1
公开(公告)日：2006-11-23
申请号：US11496187
申请日：2006-07-31
IPC分类号： B01D39/00
CPC分类号： B01D71/06 , A61M1/3633 , B01D39/163 , B01D61/14 , D04H3/05 , Y10T156/1798 , Y10T428/24 , Y10T428/24479
摘要： A non-woven polymeric matrix for separating leukocytes from a blood sample includes a non-woven three dimensional matrix formed from polymeric fibers having a predetermined pore volume fraction including a defined channel configuration, a predetermined pore size in the range of from about 10 μm to about 250 μm, and a plurality of connections between the plurality of fibers. The matrix is configured so as to remove at least about 98% of leukocytes from at least one unit of packed red blood cells. Methods of making and using the matrix are also provided.
摘要翻译： 用于从血液样品分离白细胞的无纺聚合物基质包括由具有预定孔体积分数的聚合物纤维形成的无纺三维基质，所述孔体积分数包括限定的通道构型，预定孔径在约10μm至 约250μm，以及多个光纤之间的多个连接。 该基质配置成从至少一个单位的填充的红细胞中除去至少约98％的白细胞。 还提供了制备和使用基质的方法。
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公开(公告)号：US07661541B2
公开(公告)日：2010-02-16
申请号：US11496187
申请日：2006-07-31
CPC分类号： B01D71/06 , A61M1/3633 , B01D39/163 , B01D61/14 , D04H3/05 , Y10T156/1798 , Y10T428/24 , Y10T428/24479
摘要： A non-woven polymeric matrix for separating leukocytes from a blood sample includes a non-woven three dimensional matrix formed from polymeric fibers having a predetermined pore volume fraction including a defined channel configuration, a predetermined pore size in the range of from about 10 μm to about 250 μm, and a plurality of connections between the plurality of fibers. The matrix is configured so as to remove at least about 98% of leukocytes from at least one unit of packed red blood cells. Methods of making and using the matrix are also provided.
摘要翻译： 用于从血液样品分离白细胞的无纺聚合物基质包括由具有预定孔体积分数的聚合物纤维形成的无纺三维基质，所述孔体积分数包括限定的通道构型，预定孔径在约10μm至 约250μm，以及多个光纤之间的多个连接。 该基质配置成从至少一个单位的填充的红细胞中除去至少约98％的白细胞。 还提供了制备和使用基质的方法。
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公开(公告)号：US07083697B2
公开(公告)日：2006-08-01
申请号：US10331213
申请日：2002-12-30
CPC分类号： B01D71/06 , A61M1/3633 , B01D39/163 , B01D61/14 , D04H3/05 , Y10T156/1798 , Y10T428/24 , Y10T428/24479
摘要： A non-woven polymeric matrix for separating leukocytes from a blood sample includes a non-woven three dimensional matrix formed from polymeric fibers having a predetermined pore volume fraction including a defined channel configuration, a predetermined pore size in the range of from about 10 μm to about 250 μm, and a plurality of connections between the plurality of fibers. The matrix is configured so as to remove at least about 98% of leukocytes from at least one unit of packed red blood cells. Methods of making and using the matrix are also provided.
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4.发明授权Coating dispensing system and method using a solenoid head for coating medical devices 有权涂布分配系统和使用螺线管头的方法用于涂覆医疗装置公开(公告)号：US07785652B2
公开(公告)日：2010-08-31
申请号：US12467580
申请日：2009-05-18
CPC分类号： A61L31/18 , A61F2/82 , A61F2/86 , A61F2250/0067 , A61L31/10 , A61L31/16 , A61L2300/602 , A61L2300/606 , A61L2420/02 , B05B5/082 , B05B12/122 , B05B12/124 , B05B12/16 , B05B13/0228 , B05B13/0442
摘要： System and method for coating a medical appliance is provided. In accord with one embodiment, a system for applying a coating to a medical appliance having accessible patterned surfaces is provided. The system may include: a processor, an appliance support, and a solenoid type fluid dispensing head having an electromagnetically controlled valve. In the system, the appliance support may be adapted to hold the medical appliance and to provide direct access for a coating to contact the exposed external patterned surfaces of the medical appliance. The solenoid type fluid dispensing head in this system may move with respect to the medical appliance and may be in communication with a source of coating and with the processor. The processor in this system may contain commands that instruct the solenoid type fluid dispensing head to force coating onto the accessible patterned surfaces of the medical appliance in a pattern that correlates with the accessible patterned surfaces of the medical appliance.
摘要翻译： 提供了用于涂覆医疗器具的系统和方法。 根据一个实施例，提供了一种用于将涂层施加到具有可访问的图案化表面的医疗器具的系统。 该系统可以包括：处理器，器具支架和具有电磁控制阀的螺线管型流体分配头。 在系统中，器具支撑件可以适于保持医疗器具，并且提供用于涂层的直接接触以接触医疗器具的暴露的外部图案化表面。 该系统中的螺线管式流体分配头可以相对于医疗器具移动，并且可以与涂层和处理器连通。 该系统中的处理器可以包含命令，该命令指示螺线管型流体分配头以与医疗器具的可访问的图案化表面相关联的图案强制涂覆到医疗器具的可接近图案化表面上。
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5.发明申请COATING DISPENSING SYSTEM AND METHOD USING A SOLENOID HEAD FOR COATING MEDICAL DEVICES 有权涂覆分配系统和使用用于涂敷医疗装置的电磁头的方法公开(公告)号：US20090226601A1
公开(公告)日：2009-09-10
申请号：US12467580
申请日：2009-05-18
IPC分类号： B05D3/14
CPC分类号： A61L31/18 , A61F2/82 , A61F2/86 , A61F2250/0067 , A61L31/10 , A61L31/16 , A61L2300/602 , A61L2300/606 , A61L2420/02 , B05B5/082 , B05B12/122 , B05B12/124 , B05B12/16 , B05B13/0228 , B05B13/0442
摘要： System and method for coating a medical appliance is provided. In accord with one embodiment, a system for applying a coating to a medical appliance having accessible patterned surfaces is provided. The system may include: a processor, an appliance support, and a solenoid type fluid dispensing head having an electromagnetically controlled valve. In the system, the appliance support may be adapted to hold the medical appliance and to provide direct access for a coating to contact the exposed external patterned surfaces of the medical appliance. The solenoid type fluid dispensing head in this system may move with respect to the medical appliance and may be in communication with a source of coating and with the processor. The processor in this system may contain commands that instruct the solenoid type fluid dispensing head to force coating onto the accessible patterned surfaces of the medical appliance in a pattern that correlates with the accessible patterned surfaces of the medical appliance.
摘要翻译： 提供了用于涂覆医疗器具的系统和方法。 根据一个实施例，提供了一种用于将涂层施加到具有可访问的图案化表面的医疗器具的系统。 该系统可以包括：处理器，器具支架和具有电磁控制阀的螺线管型流体分配头。 在系统中，器具支撑件可以适于保持医疗器具，并且提供用于涂层的直接接触以接触医疗器具的暴露的外部图案化表面。 该系统中的螺线管式流体分配头可以相对于医疗器具移动，并且可以与涂层和处理器连通。 该系统中的处理器可以包含命令，该命令指示螺线管型流体分配头以与医疗器具的可访问的图案化表面相关联的图案强制涂覆到医疗器具的可接近图案化表面上。
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