公开(公告)号：US20080048110A1

公开(公告)日：2008-02-28

申请号：US11878241

申请日：2007-07-23

申请人： Kisaburo DEGUCHI ,  Atsumu HIRABAYASHI ,  Hiroki ITO ,  Takashi BABA

发明人： Kisaburo DEGUCHI ,  Atsumu HIRABAYASHI ,  Hiroki ITO ,  Takashi BABA

IPC分类号： H01J49/00

CPC分类号： G01N33/6848 ,  H01J49/004

摘要： To analyze glycans and peptide sequences without liberating glycans from glycosylated peptides, a glycan structure is analyzed through negative-ion CID, in which sialic acid and fucose are resistant to elimination, and a peptide sequence is analyzed through positive-ion ECD.

摘要翻译： 为了分析聚糖和肽序列而不从糖基化肽释放聚糖，通过负离子CID分析聚糖结构，其中唾液酸和岩藻糖对消除具有抗性，并且通过正离子ECD分析肽序列。

公开(公告)号：US20090256070A1

公开(公告)日：2009-10-15

申请号：US12422382

申请日：2009-04-13

申请人： Hisashi NAGANO ,  Takashi BABA ,  Hiroyuki SATAKE

发明人： Hisashi NAGANO ,  Takashi BABA ,  Hiroyuki SATAKE

IPC分类号： B01D59/44

CPC分类号： H01J49/4245

摘要： A compact, low-cost, and simple ion trap capable of operating at a low vacuum level is provided along with technology for utilizing that ion trap to perform mass spectroscopy and analyzing ion mobility without a drop in measurement accuracy. Ions are trapped in a one dimensional potential formed by a potential comprised of a direct current voltage and a potential comprised of an alternating current voltage. The trapped ions are made to collide with an electrode by changing at least the applied direct current voltage or alternating current voltage, and are detected as an electrical current value.

摘要翻译： 提供了能够以低真空度操作的紧凑，低成本且简单的离子阱，以及利用该离子阱进行质谱分析和分析离子迁移率而不降低测量精度的技术。 离子被俘获在由直流电压和由交流电压构成的电位组成的电位形成的一维电位中。 通过至少改变施加的直流电压或交流电压使捕获的离子与电极碰撞，并且被检测为电流值。

公开(公告)号：US20100219337A1

公开(公告)日：2010-09-02

申请号：US12713522

申请日：2010-02-26

申请人： Yuichiro HASHIMOTO ,  Hideki HASEGAWA ,  Takashi BABA ,  Izumi WAKI

发明人： Yuichiro HASHIMOTO ,  Hideki HASEGAWA ,  Takashi BABA ,  Izumi WAKI

IPC分类号： H01J49/42

CPC分类号： H01J49/427 ,  H01J49/067 ,  H01J49/4225

摘要： A mass spectrometer introducing ions produced at an ion source, and including quadrupole rods which have an inlet and an outlet and to which a radio-frequency voltage is applied, the mass spectrometer, i.e., a mass spectrometry device implemented by a linear trap which exhibits high ejection efficiency, high mass resolution, and low ejection energy, executes the following steps: Trapping at least part of the ions by a trap potential generated on the central axis of a quadrupole field, oscillating part of the trapped ions in an intermediate direction between the mutually-adjacent quadrupole rods, ejecting the oscillated ions by an extraction field, and detecting the ejected ions or introducing the ejected ions into another detection process.

摘要翻译： 引入在离子源产生的离子的质谱仪，并且包括具有入口和出口的四极棒，并且施加射频电压，质谱仪即由线性陷阱实现的质谱装置，其显示出 高喷射效率，高质量分辨率和低喷射能量执行以下步骤：通过在四极场的中心轴上产生的捕获电位捕获至少一部分离子，将捕获的离子的一部分在中间方向上振荡 相邻的四极杆，通过提取场喷射振荡的离子，并检测喷射的离子或将喷射的离子引入另一检测过程。