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公开(公告)号：US06980294B2
公开(公告)日：2005-12-27
申请号：US11017506
申请日：2004-12-20
IPC分类号： G01N21/64
CPC分类号： G01N21/6458 , G01N21/6408 , G02B21/0076
摘要： A biomolecule analyzer of the present invention analyzes dynamic behaviors of biomolecules, and comprises image obtaining means for obtaining an image corresponding to at least one observation area of a biological sample containing biomolecules held in a measurable state, designation means for designating an arbitrary point on the image obtained by the image obtaining means, arrangement means for arranging a measuring point in a point position on the sample corresponding to the point designated by the designation means so that the measuring point may continuously coincide with the point position, measurement means for measuring a signal derived from dynamic information of an object to be measured from the measuring point arranged by the arrangement means, and analysis means for analyzing measuring results of the measurement means.
摘要翻译： 本发明的生物分子分析仪分析生物分子的动态行为，并且包括图像获取装置，用于获得与包含保持在可测量状态的生物分子的生物样品的至少一个观察区域相对应的图像，用于指定在可测量状态下的任意点的指定装置 由图像获得装置获得的图像，用于将测量点布置在与由指定装置指定的点相对应的样本上的点位置的测量点的布置装置，使得测量点可以与点位置连续一致，用于测量信号的测量装置 从由所述布置装置布置的测量点的待测物体的动态信息导出;以及分析装置，用于分析测量装置的测量结果。
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公开(公告)号：US07355701B2
公开(公告)日：2008-04-08
申请号：US11290264
申请日：2005-11-30
申请人： Kiyochika Ishibashi
发明人： Kiyochika Ishibashi
CPC分类号： G01N21/6456
摘要： A spectroscopy analysis apparatus contains a focusing unit which focuses light from a light source on a sample, an optical scanner which scans the light on the sample, an optical detector which detects light intensity of the light emitted from the sample, and a cross-correlation calculating unit which calculates cross-correlation between the measurement points by associating light intensity with scanning position of the optical scanner, light intensity, which is detected with the optical detector, from plural measurement points on the sample, whose position is controlled with the optical scanner.
摘要翻译： 光谱分析装置包括聚焦单元，其将来自光源的光聚焦在样品上，扫描样品上的光的光学扫描器，检测从样品发射的光的光强度的光学检测器和互相关 计算单元，其通过将光强度与光学扫描仪的扫描位置相关联并且由光学检测器检测到的光强度与样品上的多个测量点相关联来计算测量点之间的互相关，其位置由光学扫描器 。
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公开(公告)号：US07336355B2
公开(公告)日：2008-02-26
申请号：US11529017
申请日：2006-09-28
IPC分类号： G01N21/64
CPC分类号： G01N21/6408 , G01N21/6428 , G01N2021/6419 , G01N2021/6441
摘要： There is provided a fluorescence spectroscopic apparatus includes an exciting optical unit configured to irradiate the same sample area with a plurality of excitation lights of different wavelength bands, an optical unit configured to repeatedly guide fluorescences emitted by the sample in response to the respective excitation lights, to a detection unit, and a calculation unit configured to perform analysis on the basis of a comparison of output signals corresponding to the fluorescences from the detection unit, wherein the exciting optical unit includes an excitation light varying unit configured to intermittently vary the intensity of at least one excitation light.
摘要翻译： 提供了一种荧光分光装置，包括：激发光学单元，被配置为用不同波长带的多个激发光照射相同的样本区域;光学单元，被配置为响应于各个激发光反复引导样品发射的荧光， 检测单元和计算单元，其被配置为基于与来自检测单元的荧光相对应的输出信号的比较来执行分析，其中激发光学单元包括激励光改变单元，其被配置为间歇地改变在 至少一个激发光。
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公开(公告)号：US20060109461A1
公开(公告)日：2006-05-25
申请号：US11290264
申请日：2005-11-30
申请人： Kiyochika Ishibashi
发明人： Kiyochika Ishibashi
CPC分类号： G01N21/6456
摘要： A spectroscopy analysis apparatus contains a focusing unit which focuses light from a light source on a sample, an optical scanner which scans the light on the sample, an optical detector which detects light intensity of the light emitted from the sample, and a cross-correlation calculating unit which calculates cross-correlation between the measurement points by associating light intensity with scanning position of the optical scanner, light intensity, which is detected with the optical detector, from plural measurement points on the sample, whose position is controlled with the optical scanner.
摘要翻译： 光谱分析装置包括聚焦单元，其将来自光源的光聚焦在样品上，扫描样品上的光的光学扫描器，检测从样品发射的光的光强度的光学检测器和互相关 计算单元，其通过将光强度与光学扫描仪的扫描位置相关联并且由光学检测器检测到的光强度与样品上的多个测量点相关联来计算测量点之间的互相关，其位置由光学扫描器 。
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5.发明授权
公开(公告)号：US5087423A
公开(公告)日：1992-02-11
申请号：US422597
申请日：1989-10-17
申请人： Kiyochika Ishibashi
发明人： Kiyochika Ishibashi
CPC分类号： G01N35/0092 , G01N35/04 , G01N2035/0468 , G01N2035/047 , G01N2035/0472
摘要： An automatic analyzing apparatus in which a plurality of analyzing modules, a plurality of analyzing routes and at least one bypass route bypassing at least one analyzing module are arranged. Each analyzing module is capable of analyzing samples with respect to one or more items, and samples successively supplied from the introduction sides of the modules are selectively delivered into each module in accordance with the possible analyzing items of each module and the analyzing items of the samples to be analyzed. The sample cup can pass the module via a bypass or can be returned to the introduction side of the module via a bypass, in accordance with the items to be analyzed, the effective distribution of the sample cups can be performed.
摘要翻译： 一种自动分析装置，其中布置有多个分析模块，多个分析路线和绕过至少一个分析模块的至少一个旁路路线。 每个分析模块能够分析关于一个或多个项目的样本，并且根据每个模块的可能分析项目和样本的分析项目，将从模块的引入侧连续提供的样本选择性地传递到每个模块中 待分析。 样品杯可以通过旁路通过模块，或者可以通过旁路将模块返回到模块的引入侧，根据要分析的项目，可以执行样品杯的有效分布。
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公开(公告)号：US20070024964A1
公开(公告)日：2007-02-01
申请号：US11529017
申请日：2006-09-28
IPC分类号： G02B21/00
CPC分类号： G01N21/6408 , G01N21/6428 , G01N2021/6419 , G01N2021/6441
摘要： There is provided a fluorescence spectroscopic apparatus includes an exciting optical unit configured to irradiate the same sample area with a plurality of excitation lights of different wavelength bands, an optical unit configured to repeatedly guide fluorescences emitted by the sample in response to the respective excitation lights, to a detection unit, and a calculation unit configured to perform analysis on the basis of a comparison of output signals corresponding to the fluorescences from the detection unit, wherein the exciting optical unit includes an excitation light varying unit configured to intermittently vary the intensity of at least one excitation light.
摘要翻译： 提供了一种荧光分光装置，包括：激发光学单元，被配置为用不同波长带的多个激发光照射相同的样本区域;光学单元，被配置为响应于各个激发光反复引导样品发射的荧光， 检测单元和计算单元，其被配置为基于与来自检测单元的荧光相对应的输出信号的比较来执行分析，其中激发光学单元包括激励光改变单元，其被配置为间歇地改变在 至少一个激发光。
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公开(公告)号：US20050213090A1
公开(公告)日：2005-09-29
申请号：US11017506
申请日：2004-12-20
IPC分类号： G01N21/64
CPC分类号： G01N21/6458 , G01N21/6408 , G02B21/0076
摘要： A biomolecule analyzer of the present invention analyzes dynamic behaviors of biomolecules, and comprises image obtaining means for obtaining an image corresponding to at least one observation area of a biological sample containing biomolecules held in a measurable state, designation means for designating an arbitrary point on the image obtained by the image obtaining means, arrangement means for arranging a measuring point in a point position on the sample corresponding to the point designated by the designation means so that the measuring point may continuously coincide with the point position, measurement means for measuring a signal derived from dynamic information of an object to be measured from the measuring point arranged by the arrangement means, and analysis means for analyzing measuring results of the measurement means.
摘要翻译： 本发明的生物分子分析仪分析生物分子的动态行为，并且包括图像获取装置，用于获得与包含保持在可测量状态的生物分子的生物样品的至少一个观察区域相对应的图像，用于指定在可测量状态下的任意点的指定装置 由图像获得装置获得的图像，用于将测量点布置在与由指定装置指定的点相对应的样本上的点位置的测量点的布置装置，使得测量点可以与点位置连续一致，用于测量信号的测量装置 从由所述布置装置布置的测量点的待测物体的动态信息导出;以及分析装置，用于分析测量装置的测量结果。
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公开(公告)号：US5200052A
公开(公告)日：1993-04-06
申请号：US802872
申请日：1991-12-06
申请人： Kiyochika Ishibashi
发明人： Kiyochika Ishibashi
IPC分类号： G01N1/00 , G01N27/28 , G01N27/416 , G01N33/487 , G01N35/08
CPC分类号： G01N35/08 , G01N33/4915
摘要： An ion concentration analyzer for determining ion concentration in blood or urine. This analyzer comprises a flow cell provided with an ion selecting electrode and a syringe having a metal piston rod for introducing sample liquid into the flow cell. A metal member is disposed at a mid portion of a pipe connecting the flow cell and the syringe, and is electrically connected to the piston rod.
摘要翻译： 用于测定血液或尿液中的离子浓度的离子浓度分析仪。 该分析仪包括设置有离子选择电极的流动池和具有用于将样品液体引入到流动池中的金属活塞杆的注射器。 金属构件设置在连接流动池和注射器的管道的中部，并且与活塞杆电连接。
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