公开(公告)号：US12180505B2

公开(公告)日：2024-12-31

申请号：US17246376

申请日：2021-04-30

Applicant: Korea University Research and Business Foundation

Inventor： Heemin Kang ,  Young Keun Kim ,  Sunhong Min ,  Yoo Sang Jeon ,  Hyojun Choi

IPC: C12N5/0775 ,  C07K5/09

Abstract: Disclosed are a nanobarcode for controlling adhesion and differentiation of stem cells and a method of controlling adhesion and differentiation of stem cells by using nanobarcodes. The method of controlling adhesion and differentiation of stem cells of the present invention may efficiently control adhesion and differentiation of stem cells in vivo or in vitro by tuning periodicity and sequences of a ligand peptide (RGD) of a nanobarcode.

公开(公告)号：US20240387081A1

公开(公告)日：2024-11-21

申请号：US18406988

申请日：2024-01-08

Applicant: Korea University Research and Business Foundation

Inventor： Heemin KANG ,  Sunhong Min ,  Hyunshik Hong ,  Seong Yeol Kim ,  Kanghyeon Kim ,  Chowon Kim

IPC: H01F1/00

Abstract: Disclosed is a magnetic structure having a spike structure, the magnetic structure comprising: a core including at least one magnetic nanoparticle; a buffer disposed on an outer surface of the core; a shell disposed on an outer surface of the buffer, and at least one spike structure protruding outwardly from the shell, wherein the spike structure is controlled to have various shapes.

公开(公告)号：US12297456B2

公开(公告)日：2025-05-13

申请号：US18199013

申请日：2023-05-18

Applicant: Korea University Research and Business Foundation

Inventor： Heemin Kang ,  Young Keun Kim ,  Sunhong Min ,  Yoo Sang Jeon ,  Hyojun Choi

IPC: C12N5/0775 ,  C07K5/09

Abstract: Disclosed are a nanobarcode for controlling adhesion and differentiation of stem cells and a method of controlling adhesion and differentiation of stem cells by using nanobarcodes. The method of controlling adhesion and differentiation of stem cells of the present invention may efficiently control adhesion and differentiation of stem cells in vivo or in vitro by tuning periodicity and sequences of a ligand peptide (RGD) of a nanobarcode.

公开(公告)号：US11981751B2

公开(公告)日：2024-05-14

申请号：US17246403

申请日：2021-04-30

Applicant: Korea University Research and Business Foundation

Inventor： Heemin Kang ,  Young Keun Kim ,  Sunhong Min ,  Yoo Sang Jeon ,  Hyojun Choi

IPC: C07K5/08 ,  C07K5/09 ,  C12N5/0786

CPC classification number: C07K5/0817 ,  C12N5/0645

Abstract: Disclosed are a nanobarcode for controlling adhesion and polarization of macrophages and a method of controlling adhesion and polarization of macrophages by using nanobarcodes. The method of controlling adhesion and polarization of macrophages of the present invention may efficiently control adhesion and phenotypic polarization of macrophages in vivo or in vitro by tuning periodicity and sequences of ligand peptide (RGD) of a nanobarcode.