公开(公告)号：US11908128B2

公开(公告)日：2024-02-20

申请号：US16996087

申请日：2020-08-18

Applicant: L'Oreal

Inventor： Ruowei Jiang ,  Irina Kezele ,  Zhi Yu ,  Sophie Seite ,  Frederic Antoinin Raymond Serge Flament ,  Parham Aarabi ,  Mathieu Perrot ,  Julien Despois

IPC: G06T7/00 ,  A61B5/00 ,  G16H50/20 ,  G06Q30/0601

CPC classification number: G06T7/0012 ,  A61B5/0077 ,  A61B5/441 ,  A61B5/7267 ,  G06Q30/0631 ,  G06Q30/0633 ,  G06Q30/0641 ,  G16H50/20 ,  G06T2207/20076 ,  G06T2207/20081 ,  G06T2207/20084 ,  G06T2207/30088 ,  G06T2207/30201

Abstract: Systems and methods process images to determine a skin condition severity analysis and to visualize a skin analysis such as using a deep neural network (e.g. a convolutional neural network) where a problem was formulated as a regression task with integer-only labels. Auxiliary classification tasks (for example, comprising gender and ethnicity predictions) are introduced to improve performance. Scoring and other image processing techniques may be used (e.g. in assoc. with the model) to visualize results such as highlighting the analyzed image. It is demonstrated that the visualization of results, which highlight skin condition affected areas, can also provide perspicuous explanations for the model. A plurality (k) of data augmentations may be made to a source image to yield k augmented images for processing. Activation masks (e.g. heatmaps) produced from processing the k augmented images are used to define a final map to visualize the skin analysis.

公开(公告)号：US20160235791A1

公开(公告)日：2016-08-18

申请号：US15024620

申请日：2014-09-25

Applicant: L'OREAL

Inventor： Richard Martin ,  Sophie Seite ,  Anne Colonna

IPC: A61K35/74 ,  C12Q1/68 ,  C12N1/20 ,  G01N33/569 ,  A61K8/99 ,  A61Q19/00

CPC classification number: A61K35/74 ,  A61K8/99 ,  A61K9/0014 ,  A61K9/06 ,  A61K47/02 ,  A61K47/26 ,  A61Q19/007 ,  C12N1/20 ,  C12Q1/04 ,  C12Q1/689 ,  C12Q2600/118 ,  G01N33/56911 ,  G01N2333/195 ,  G01N2800/202 ,  G01N2800/50 ,  G01N2800/52

Abstract: This invention relates to a dermatological composition comprising, as an active ingredient, bacteria of at least one Stenotrophomonas strain and/or at least one Stenotrophomonas growth inducer, and the use thereof in the prevention and/or treatment of atopic dermatitis. This invention also relates to an in vitro method for prognosis and/or diagnosis of atopic dermatitis and a method for selecting a Stenotrophomonas growth inducer.

Abstract translation: 本发明涉及皮肤病学组合物，其包含作为活性成分的至少一种Stenotrophomonas菌株和/或至少一种Stenotrophomonas生长诱导物的细菌，以及其在预防和/或治疗特应性皮炎中的用途。 本发明还涉及用于特应性皮炎的预后和/或诊断的体外方法以及选择嗜麦芽寡养单宁生长诱导剂的方法。

公开(公告)号：US20160215326A1

公开(公告)日：2016-07-28

申请号：US15024683

申请日：2014-09-25

Applicant: L'OREAL

Inventor： Richard Martin ,  Sophie Seite

IPC: C12Q1/68

CPC classification number: C12Q1/689 ,  C12Q1/025 ,  C12Q2600/118 ,  C12Q2600/136 ,  C12Q2600/158 ,  G01N33/6893 ,  G01N2800/202 ,  G01N2800/52

Abstract: This invention relates to the characterization of the bacterial signature associated with atopic dermatitis and the use thereof in in vitro methods for prognosis and/or diagnosis of atopic dermatitis, methods for monitoring response to a treatment, methods for monitoring the development of atopic dermatitis, as well as methods for selecting compounds useful in the prevention and/or treatment of atopic dermatitis.

Abstract translation: 本发明涉及与特应性皮炎相关的细菌特征的表征及其在用于预测和/或诊断特应性皮炎的体外方法中的应用，用于监测对治疗的反应的方法，用于监测特应性皮炎发展的方法，如 以及用于选择可用于预防和/或治疗特应性皮炎的化合物的方法。