公开(公告)号：US20180116936A1

公开(公告)日：2018-05-03

申请号：US15339026

申请日：2016-10-31

Applicant: L'OREAL

Inventor： Zhi PAN ,  Ashleigh MURTAUGH ,  Fan HU ,  Yan YU

IPC: A61K8/49 ,  A61K8/36 ,  A61K8/67 ,  A61K8/60 ,  A61K8/97 ,  A61K8/06 ,  A61Q19/08

CPC classification number: A61K8/498 ,  A61K8/062 ,  A61K8/064 ,  A61K8/36 ,  A61K8/365 ,  A61K8/4926 ,  A61K8/4953 ,  A61K8/602 ,  A61K8/675 ,  A61K8/676 ,  A61K8/97 ,  A61K2800/10 ,  A61K2800/522 ,  A61K2800/592 ,  A61Q19/00 ,  A61Q19/08

Abstract: Compositions comprising an isolate or extract comprising mangiferin, one or more of ferulic acid, Vitamin C, and baicalin, present in amounts sufficient to produce synergistic antioxidant activity and provided for cosmetic and other uses.

公开(公告)号：US20210338564A1

公开(公告)日：2021-11-04

申请号：US17377477

申请日：2021-07-16

Applicant: L'OREAL

Inventor： Andrea ELSEN-WAHRER ,  Jim SINGER ,  Paul BONVALLET ,  Zhi PAN

IPC: A61K8/97 ,  A61K8/60 ,  A61K8/368 ,  A61K8/49 ,  A61K8/44 ,  A61K8/22 ,  A61K8/19 ,  A61K8/24 ,  A61K8/34 ,  A61K8/42 ,  A61K8/23 ,  A61Q5/08 ,  A61Q5/10 ,  A61K8/365 ,  A61K8/36 ,  A61Q5/06

Abstract: The present invention relates to a cosmetic treatment and processes for treating keratinous materials, in particular for altering the color of hair as in hair coloration, hair color lightening or removal, and treatment of artificially colored hair, wherein the composition can include at least one antioxidant, applied separately or combined or combinable with one or more components of a color altering system in amounts sufficient to confer protection when the treatment composition is applied to keratinous material and thereby enhance and protect one or more sensorial features, and preserve the mechanical properties and native amino acid structure of the keratinous material.

公开(公告)号：US20190224100A1

公开(公告)日：2019-07-25

申请号：US16369912

申请日：2019-03-29

Applicant: L'OREAL

Inventor： Zhi PAN ,  Maolin Guo ,  Anne-Laure Suzanne Bernard ,  Yim Sunghan

IPC: A61K8/60 ,  A61K8/06 ,  A61K8/49 ,  A61K8/891 ,  A61Q17/04 ,  A61K8/97 ,  A61K8/99 ,  A61K8/67

Abstract: The present disclosure relates to compositions and methods for providing full spectrum photo protection to skin, which includes protection from infrared (IR) radiation and/or visible light in addition to protection from UV radiation. The compositions typically include: (a) baicalin; (b) one or more antioxidants selected from the group consisting of VENUCEANE (Thermus thermophiles ferment), polydatin, hesperetin, mango leaf extract, vitamin C; (c) optionally, one or more solubilizers; and (d) a cosmetically acceptable carrier. The compositions are unique in that the combination of (a), (b), optional (c), and (d) alone, provide at least full spectrum protection from ultraviolet radiation (UV), visible light, and infrared radiation (IR). The composition can additionally, optionally, include one or more UV filters to further enhance protection from UV radiation.

公开(公告)号：US20190298638A1

公开(公告)日：2019-10-03

申请号：US15939422

申请日：2018-03-29

Applicant: L'OREAL

Inventor： Zhi PAN ,  Anne -Laure Suzanne BERNARD ,  Yang DENG

IPC: A61K8/60 ,  A61Q17/04 ,  A61K8/35 ,  A61K8/34 ,  A61K8/36 ,  A61K8/37 ,  A61K8/40 ,  A61K8/49 ,  A61K8/86 ,  A61K8/891 ,  A61K8/895

Abstract: Methods for providing broad spectrum photo protection to skin using antioxidants that provide UVA protection to skin are described. The methods include topically applying a cosmetic composition comprising: (a) at least one antioxidant having an Oxygen Radical Absorbance Capacity (ORAC) of at least 10,000 μmol TE/g and a Hydroxyl Radical Absorbance Capacity (HORAC) of at least 2,600 μmol GAE/g; (b) at least one organic UV filter; and (c) a cosmetically acceptable carrier; wherein the cosmetic composition provides an increase in UVAPPD PF of at least 30% relative to an otherwise identical cosmetic composition without the antioxidant(s) of (a). The disclosure also relates to the cosmetic compositions useful in the described methods.

公开(公告)号：US20190029930A1

公开(公告)日：2019-01-31

申请号：US16047632

申请日：2018-07-27

Applicant: L'OREAL

Inventor： Yang DENG ,  Alexandra Jane Elise FARRAN ,  Anne-Laure Suzanne BERNARD ,  Hy Si BUI ,  Zhi PAN

IPC: A61K8/06 ,  A61Q19/08 ,  A61K8/81 ,  A61K8/31 ,  A61K8/58

Abstract: The disclosure relates to compositions, films, and methods for improving the appearance of the skin. Compositions comprise an oil phase comprising at least one thermoplastic elastomer, at least one adhesive polymer, and a surfactant; an aqueous phase comprising water, a solvent, and a salt; and at least one filler, which together form an association in the composition. Methods comprise applying the compositions to the skin to tighten the skin or hide skin imperfections, by forming a film on the skin.

公开(公告)号：US20180177706A1

公开(公告)日：2018-06-28

申请号：US15390220

申请日：2016-12-23

Applicant: L'OREAL

Inventor： Zhi PAN ,  Anne-Laure Suzanne BERNARD ,  Hy Si BUI ,  Fan HU

IPC: A61K8/73 ,  A61K8/97 ,  A61K8/49 ,  A61K9/00

CPC classification number: A61K8/735 ,  A61K8/9794 ,  A61K9/0014 ,  A61K9/0019 ,  A61K9/0021 ,  A61K31/704 ,  A61K31/728 ,  A61K36/88 ,  A61K45/06 ,  A61K47/36 ,  A61K47/46 ,  A61K2800/91 ,  A61P17/00 ,  A61Q19/001 ,  A61Q19/007 ,  A61K2300/00

Abstract: Compositions comprising a hyaluronic acid adjuvant system comprising hyaluronic acid, purple rice extract and dipotassium glycyrrhizate, present together in amounts sufficient to produce synergistic anti-hyaluronidase activity, and provided for cosmetic and other uses.

公开(公告)号：US20180116950A1

公开(公告)日：2018-05-03

申请号：US15339036

申请日：2016-10-31

Applicant: L'OREAL

Inventor： Zhi PAN ,  Ashleigh MURTAUGH ,  Fan HU

IPC: A61K8/97 ,  A61K8/60 ,  A61K8/67 ,  A61K8/49 ,  A61K8/06 ,  A61Q19/08

Abstract: Compositions comprising at least one polyphenol selected from the group consisting of Silybum Marianum extract, Origanum Vulgare leaf extract, and Coptis Chinensis root extract, and baicalin, and Vitamin E, all present in amounts sufficient to produce synergistic antioxidant activity and provided for cosmetic and other uses.

公开(公告)号：US20230310534A1

公开(公告)日：2023-10-05

申请号：US18118316

申请日：2023-03-07

Applicant: L'OREAL ,  Yale University

Inventor： Kelly Marie GEORGE ,  Zhi PAN ,  Laurent MARROT ,  Miao WANG ,  Douglas Edgar BRASH ,  Sanjay PREMI ,  Leticia C.P. GONCALVES

IPC: A61K36/704 ,  A61K31/01 ,  A61K36/04 ,  A61K47/12 ,  A61K47/24 ,  A61K36/539 ,  A61K36/287 ,  A61K31/192 ,  A61K31/12 ,  A61K31/353 ,  A61K36/48 ,  A61K31/19 ,  A61K31/44 ,  A61K36/355 ,  A61K31/015 ,  A61K31/366 ,  A61K8/9717 ,  A61K8/44 ,  A61K8/49 ,  A61K8/9789 ,  A61K8/36 ,  A61Q19/00 ,  A61K8/365 ,  A61K8/31 ,  A61K8/40 ,  A61K8/35

CPC classification number: A61K36/704 ,  A61K31/01 ,  A61K36/04 ,  A61K47/12 ,  A61K47/24 ,  A61K36/539 ,  A61K36/287 ,  A61K31/192 ,  A61K31/12 ,  A61K31/353 ,  A61K36/48 ,  A61K31/19 ,  A61K31/44 ,  A61K36/355 ,  A61K31/015 ,  A61K31/366 ,  A61K8/9717 ,  A61K8/44 ,  A61K8/498 ,  A61K8/9789 ,  A61K8/4926 ,  A61K8/36 ,  A61Q19/004 ,  A61K8/365 ,  A61K8/31 ,  A61K8/40 ,  A61K8/35

Abstract: A method for decreasing formation of one or more chemiexcitation-induced dark cyclobutane pyrimidine dimers (dCPDs) in a cell or DNA molecule in a subject, who has been exposed to UV radiation, is provided. The method comprises administering to the subject an effective amount of a dCPD quencher within 8 hours after the exposure. The dCPD quencher is selected from the group consisting of ellagic acid, Porphyra Umbilicalis Extract (including Porphyra Umbilicalis Extract (and) Sodium Lactate (and) Lecithin), mycosporine-like amino acids (MAAs) and synthetic analogues thereof, Scutellaria Baicalensis Root Extract, Chrysanthemum Morifolium Leaf Extract, ferulic acid, fused-ring cyanoacrylates, curcumin, epigallocatechin gallate, Scutellaria Baicalensis Root Extract (and) Acacia Catechu Wood Extract, sorbic acid, Polygonum Cuspidatum Root Extract, Acacia Catechu Extract, dipicolinic acid, squalene, Lonicera Japonica (Honeysuckle) Flower Extract, beta-carotene and combinations thereof. The dCPD quencher may be administered to the subject in the absence of UV radiation.

公开(公告)号：US20190159989A1

公开(公告)日：2019-05-30

申请号：US15827101

申请日：2017-11-30

Applicant: L'OREAL

Inventor： Yang DENG ,  Zhi PAN ,  Anne-Laure Suzanne BERNARD ,  Shan WU

IPC: A61K8/49 ,  A61Q17/00 ,  A61Q17/04 ,  A61Q19/08 ,  A61K8/06 ,  A61K8/67 ,  A61K8/73

Abstract: A cosmetic composition and a method of preparing a cosmetic composition that includes mangiferin characterized as demonstrating soluble and chemically stable mangiferin, wherein stability includes resistance to crystallization of mangiferin that is independent of temperature and pH.

公开(公告)号：US20180280286A1

公开(公告)日：2018-10-04

申请号：US15476477

申请日：2017-03-31

Applicant: L'OREAL

Inventor： Andrea ELSEN-WAHRER ,  Jim SINGER ,  Paul BONVALLET ,  Zhi PAN

IPC: A61K8/97 ,  A61K8/60 ,  A61K8/368 ,  A61K8/49 ,  A61K8/44 ,  A61K8/22 ,  A61K8/19 ,  A61K8/24 ,  A61K8/34 ,  A61K8/42 ,  A61K8/23 ,  A61Q5/08 ,  A61Q5/10

Abstract: The present invention relates to a cosmetic treatment and processes for treating keratinous materials, in particular for altering the color of hair as in hair coloration, hair color lightening or removal, and treatment of artificially colored hair, wherein the composition can include at least one antioxidant, applied separately or combined or combinable with one or more components of a color altering system in amounts sufficient to confer protection when the treatment composition is applied to keratinous material and thereby enhance and protect one or more sensorial features, and preserve the mechanical properties and native amino acid structure of the keratinous material.