公开(公告)号：US20160139020A1

公开(公告)日：2016-05-19

申请号：US14891465

申请日：2013-05-16

Applicant: L'OREAL

Inventor： Alexandre Nicolas ,  Sébastien Gregoire ,  Christophe Provin ,  Christophe Hadjur ,  Teruo Fujii

IPC: G01N13/00 ,  G01N27/403 ,  G01N27/07 ,  G01N21/84

CPC classification number: G01N13/00 ,  G01N13/04 ,  G01N15/082 ,  G01N21/84 ,  G01N27/07 ,  G01N27/403 ,  G01N2013/003

Abstract: The invention relates to an installation (1) for determining the diffusion profile of at least one molecule through skin, comprising: a microfluidic chip (4) comprising: a donor compartment (10) intended to contain a test solution comprising the or each molecule; a receptor compartment (12) intended to contain a receptor solution; and a membrane (14) with skin-mimetic barrier properties arranged between the donor compartment (10) and the receptor compartment (12) so that the test solution diffuses through the membrane (14) from the donor compartment (10) into the receptor compartment (12); and an analyzer (8) for measuring a physical parameter of the solution contained in the receptor compartment (12) as the test solution diffuses through the membrane (14), and said analyzer (8) being configured for measuring the physical parameter in the receptor compartment (12), the analyzer (8) being further configured for calculating the diffusion profile of the or each molecule through skin from the measured physical parameter.

Abstract translation: 本发明涉及一种用于确定通过皮肤的至少一种分子的扩散分布的装置（1），其包括：微流体芯片（4），包括：供体隔室（10），用于容纳包含所述或每个分子的测试溶液; 旨在含有受体溶液的受体隔室（12）; 以及膜（14），其具有布置在供体室（10）和受体隔室（12）之间的皮肤模拟阻挡性质，使得测试溶液通过膜（14）从供体隔室（10）扩散到受体隔室 （12）; 以及分析器（8），用于当所述测试溶液通过所述膜（14）扩散时，测量包含在所述受体室（12）中的溶液的物理参数，并且所述分析器（8）被配置为测量所述受体中的物理参数 隔室（12），分析器（8）还被配置为从测量的物理参数计算皮肤或每个分子的扩散分布。

公开(公告)号：US20230417670A1

公开(公告)日：2023-12-28

申请号：US18253016

申请日：2021-11-12

Applicant: L'Oreal

Inventor： Alexandre Nicolas ,  Chin Kai Lee ,  Charlotte Pellet ,  Woo Ram Park

IPC: G01N21/64 ,  G01N21/84

CPC classification number: G01N21/6408 ,  G01N21/8422 ,  G01N2021/6419 ,  G01N2021/8427

Abstract: A method for determining UV coverage on an irradiation target in real time comprises the steps of irradiating an irradiation target (10) with light including UV light (16) immediately after applying a sunscreen (12); detecting an amount of fluorescent light (20) emitted from the irradiation target in response to the light irradiation and storing the amount of the fluorescent light as reference data; irradiating the irradiation target (10) with the light including UV light (16) after a predetermined passage of time, or after applying a predetermined stress on the sunscreen (12); detecting an amount of fluorescent light (20) emitted from the irradiation target in response to the light irradiation and storing the amount of the fluorescent light as measurement data; and determining UV coverage by dividing the amount of the fluorescent light of the reference data by the amount of the fluorescent light of the measurement data, wherein the irradiation target (10) includes at least one substance emitting fluorescent light in response to the light irradiation.

公开(公告)号：US20160159665A1

公开(公告)日：2016-06-09

申请号：US14781100

申请日：2014-03-28

Applicant: L'OREAL

Inventor： Alexandre Nicolas ,  Christophe Hadjur

IPC: C02F1/24 ,  A45D19/10

CPC classification number: C02F1/24 ,  A45D19/10 ,  A45D44/02 ,  C02F1/20 ,  C02F1/283 ,  C02F1/60 ,  C02F1/78 ,  C02F2001/007 ,  C02F2101/301 ,  C02F2103/002 ,  C02F2103/026 ,  C02F2201/006

Abstract: This system (18) comprises a holding and separating tank (36), an inlet (38) for moving untreated waste water into the holding tank (36), and a bubble generator (32), able to introduce a quantity of bubbles into the waste water of the holding tank (36), in order to form, in a lower region (50) of the holding tank (36), a treated water and, in an upper region (52) of the holding tank (36), a supernatant.The system (18) comprises a lower outlet (40) for recovering a treated water from the holding tank (36) and an upper outlet (42) for discharging a foamy supernatant from the holding tank (36).The system (18) is devoid of means for injecting a compound for flocculating and/or coagulating the waste water, at least upstream from the holding tank (36).

Abstract translation: 该系统（18）包括保持和分离罐（36），用于将未经处理的废水移动到储存箱（36）中的入口（38），以及气泡发生器（32），其能够将一定数量的气泡引入 为了在储存箱（36）的下部区域（50）中形成处理水，并且在储存箱（36）的上部区域（52）中形成储存罐（36）的废水， 上清液 系统（18）包括用于从储存罐（36）回收处理过的水的下出口（40）和用于从保持罐（36）排出泡沫状上清液的上出口（42）。 系统（18）至少在储存罐（36）的上游没有用于注入用于絮凝和/或凝结废水的化合物的装置。