公开(公告)号：US20150322522A1

公开(公告)日：2015-11-12

申请号：US14708467

申请日：2015-05-11

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Julio MULERO ,  Michael Malicdem ,  Robert Lagace

IPC: C12Q1/68

CPC classification number: C12Q1/6883 ,  C12Q1/6858 ,  C12Q1/6888 ,  C12Q2525/117 ,  C12Q2563/107 ,  C12Q2600/156

Abstract: Disclosed are methods for human identification utilizing newly discovered single nucleotide polymorphisms (SNPs) within CODIS loci which can cause allelic dropout. Also disclosed are kits useful in human identification.

Abstract translation: 本发明公开了利用新近发现的CODIS基因座单核苷酸多态性（SNPs）进行人类鉴定的方法，可以导致等位基因脱落。 还公开了可用于人类鉴定的试剂盒。

公开(公告)号：US20220205023A1

公开(公告)日：2022-06-30

申请号：US17585161

申请日：2022-01-26

Applicant: Life Technologies Corporation

Inventor： Robert GREEN ,  Dennis WANG ,  Julio MULERO ,  Robert LAGACE

IPC: C12Q1/6827 ,  C12Q1/6888

Abstract: Disclosed are primer set compositions, methods and kits for human identification using the highly complex sequence locus, SE33 (ACTBP2) in single and multiplex PCR reactions. Additionally, disclosed are three newly discovered single nucleotide polymorphisms (SNPs) within the SE33 locus that can cause discordance seen as mobility shift or allelic dropout. Also disclosed are kits useful in human identification.