公开(公告)号：US20160376548A1

公开(公告)日：2016-12-29

申请号：US15198237

申请日：2016-06-30

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Richard FIKE ,  Shawn BARRETT ,  Zhou JIANG ,  David JUDD

IPC: C12N5/00 ,  B01J13/22 ,  B01J13/06

CPC classification number: C12N5/005 ,  B01J13/06 ,  B01J13/22 ,  B29C67/24 ,  B29L2009/00 ,  C12N5/0018 ,  C12N2500/30 ,  C12N2500/38 ,  C12N2511/00 ,  C12N2533/40 ,  C12N2533/74

Abstract: Compositions and methods are described for preparing media, feeds, and supplements. Such methods and medias may display increased stability of labile components and may use, for example, microsuspension and/or encapsulation technologies, chelation, and optionally, coating and/or mixing the labile compounds with anti-oxidants. The compositions may withstand thermal and/or irradiation treatment and have reduced virus number. These techniques may result in product with extended shelf-life, extended release of their internal components into culture, or in product that can be added aseptically into a bioreactor using minimal volumes. The compositions and methods may optimize the bioproduction workflow and increase efficiency.

公开(公告)号：US20200332250A1

公开(公告)日：2020-10-22

申请号：US16918838

申请日：2020-07-01

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Richard FIKE ,  Shawn BARRETT ,  Zhou JIANG ,  David JUDD

IPC: C12N5/00 ,  B29C67/24 ,  B01J13/06 ,  B01J13/22

Abstract: Compositions and methods are described for preparing media, feeds, and supplements. Such methods and medias may display increased stability of labile components and may use, for example, microsuspension and/or encapsulation technologies, chelation, and optionally, coating and/or mixing the labile compounds with anti-oxidants. The compositions may withstand thermal and/or irradiation treatment and have reduced virus number. These techniques may result in product with extended shelf-life, extended release of their internal components into culture, or in product that can be added aseptically into a bioreactor using minimal volumes. The compositions and methods may optimize the bioproduction workflow and increase efficiency.

公开(公告)号：US20180346872A1

公开(公告)日：2018-12-06

申请号：US16054601

申请日：2018-08-03

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Richard FIKE ,  Shawn BARRETT ,  Zhou JIANG ,  David JUDD

IPC: C12N5/00 ,  B01J13/22 ,  B29C67/24 ,  B01J13/06 ,  B29L9/00

CPC classification number: C12N5/005 ,  B01J13/06 ,  B01J13/22 ,  B29C67/24 ,  B29L2009/00 ,  C12N5/0018 ,  C12N2500/30 ,  C12N2500/38 ,  C12N2511/00 ,  C12N2533/40 ,  C12N2533/74

Abstract: Compositions and methods are described for preparing media, feeds, and supplements. Such methods and medias may display increased stability of labile components and may use, for example, microsuspension and/or encapsulation technologies, chelation, and optionally, coating and/or mixing the labile compounds with anti-oxidants. The compositions may withstand thermal and/or irradiation treatment and have reduced virus number. These techniques may result in product with extended shelf-life, extended release of their internal components into culture, or in product that can be added aseptically into a bioreactor using minimal volumes. The compositions and methods may optimize the bioproduction workflow and increase efficiency.