公开(公告)号：US20170046504A1

公开(公告)日：2017-02-16

申请号：US15118757

申请日：2015-02-24

Applicant: LTS Lohmann Therapie-Systeme AG

Inventor： Hanshermann Franke ,  Patrick Mohr ,  René Eifler ,  Marius Bauer

IPC: G06F19/00

CPC classification number: G16C20/50 ,  G16B35/00 ,  G16C20/30 ,  G16C20/60

Abstract: A device and a method for determining a suitability of an active ingredient to be applied transdermally or transmucosally. In particular, a system that includes: at least one input device for inputting at least one designation of an active ingredient; a database for storing a plurality of data at least relating to the active ingredient; a computing unit for assessing a suitability of the active ingredient to be applied transdermally and/or transmucosally while taking into consideration data entered via the input device and/or data stored in the database; and an output device for displaying the assessed suitability.

Abstract translation: 本发明的目的是提供一种用于确定经皮或经粘膜应用的活性成分的适用性的装置和方法。 这通过包括以下的系统来实现： - 用于输入活性成分的至少一个指定的至少一个输入装置（101） - 数据库（110），用于存储至少与活性成分有关的多个数据; - 计算单元（102），用于评估通过经皮和/或经粘膜施用的活性成分的适用性，同时考虑经由输入装置（101）输入的数据和/或存储在数据库（110）中的数据; 以及 - 用于显示所评估的适用性的输出装置（103）。

公开(公告)号：US11464760B2

公开(公告)日：2022-10-11

申请号：US16772776

申请日：2018-12-13

Applicant: LTS Lohmann Therapie-Systeme AG

Inventor： Michael Linn ,  Christoph Schmitz ,  Hanshermann Franke

IPC: A61K31/4045 ,  A61K9/00 ,  A61K9/70 ,  A61K31/404 ,  A61K31/422 ,  A61K31/454 ,  A61K47/12 ,  A61K47/32

Abstract: The present invention relates to frigostable compositions suitable for iontophoretic transdermal delivery of a triptan compound that includes: a salt of a triptan compound, preferably sumatriptan succinate, a polyamine, one or more dicarboxylic acids, 0.5 to 10.0 wt.-% (based on the total weight of the composition) of one or more monocarboxylic acids, and water or an aqueous solvent mixture. The invention further relates to the use of the composition as an integral component of an iontophoretic patch, preferably as an anodic reservoir of the patch.

公开(公告)号：US11744806B2

公开(公告)日：2023-09-05

申请号：US16772775

申请日：2018-12-13

Applicant: LTS Lohmann Therapie-Systeme AG

Inventor： Michael Linn ,  Christoph Schmitz ,  Hanshermann Franke

IPC: A61K9/70 ,  A61K9/00 ,  A61K31/4045 ,  A61K47/12 ,  A61K47/34

CPC classification number: A61K9/703 ,  A61K9/0009 ,  A61K31/4045 ,  A61K47/12 ,  A61K47/34

Abstract: The present invention relates to frigostable compositions suitable for iontophoretic transdermal delivery of a triptan compound. The inventive compositions include a salt of a triptan compound, preferably sumatriptan succinate, a polyamine, a dicarboxylic acid, and water or an aqueous solvent mixture, with the composition being free of monocarboxylic acids. The invention further relates to the use of the composition as an integral component of an iontophoretic patch, preferably as an anodic reservoir of the patch.

公开(公告)号：US20210287764A1

公开(公告)日：2021-09-16

申请号：US17303519

申请日：2021-06-01

Applicant: LTS Lohmann Therapie-Systeme AG

Inventor： Hanshermann Franke ,  Patrick Mohr ,  René Eifler ,  Marius Bauer

IPC: G16C20/50 ,  G16C20/30 ,  G16C20/64

Abstract: A device and a method for determining a suitability of an active ingredient to be applied transdermally or transmucosally. In particular, a system that includes: at least one input device for inputting at least one designation of an active ingredient; a database for storing a plurality of data at least relating to the active ingredient; a computing unit for assessing a suitability of the active ingredient to be applied transdermally and/or transmucosally while taking into consideration data entered via the input device and/or data stored in the database; and an output device for displaying the assessed suitability.