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    Contrast-enhanced cone beam X-ray imaging, evaluation, monitoring and treatment delivery
    1.
    发明授权
    Contrast-enhanced cone beam X-ray imaging, evaluation, monitoring and treatment delivery 有权
    对比增强锥束X射线成像，评估，监测和治疗交付

    公开(公告)号：US07660384B2

    公开(公告)日：2010-02-09

    申请号：US12126224

    申请日：2008-05-23

    Applicant: Larry Partain ,  Stavros Prionas ,  Edward Seppi ,  Robert Sutherland ,  David Humber ,  Hassan Mostafavi ,  Felix Fernando ,  John Boone

    Inventor： Larry Partain ,  Stavros Prionas ,  Edward Seppi ,  Robert Sutherland ,  David Humber ,  Hassan Mostafavi ,  Felix Fernando ,  John Boone

    IPC: A61B6/04

    CPC classification number: A61B6/4241 ,  A61B6/032 ,  A61B6/4085 ,  A61B6/482 ,  A61B6/502 ,  A61B6/507

    Abstract: A method of imaging a patient's uncompressed region of interest using X-ray cone beam computed tomography or cone beam digital tomography comprises the step of introducing an effective amount of a contrast agent to the uncompressed region of interest. A system for imaging a patient's uncompressed region of interest using cone beam computed tomography (CBCT) or cone beam digital tomography (CBDT) comprises an X-ray source transmitting an X-ray to the uncompressed region of interest, an image acquisition system acquiring a plurality of two-dimensional projection images data for a CBCT or CBDT data set with at least one of the projection images acquired in 35 milliseconds or less, and a processor generating a three-dimensional computed tomography image data set resolving voxels with dimensions of 0.4 mm or less in at least two orthogonal directions.

    Abstract translation: 使用X射线锥束计算机断层摄影或锥束数字断层摄影术对患者未压缩感兴趣区域成像的方法包括将有效量的造影剂引入未压缩感兴趣区域的步骤。 使用锥形束计算机断层摄影（CBCT）或锥束数字断层摄影（CBDT）对患者未压缩感兴趣区域成像的系统包括将X射线发射到感兴趣的未压缩区域的X射线源，获取 多个用于CBCT或CBDT数据集的二维投影图像数据，其具有在35毫秒或更短时间内获取的至少一个投影图像，以及处理器生成三维计算机断层摄影图像数据集，其解析尺寸为0.4mm的体素 或至少两个正交方向。

    Contrast-enhanced cone beam X-ray imaging, evaluation, monitoring and treatment delivery
    2.
    发明申请
    Contrast-enhanced cone beam X-ray imaging, evaluation, monitoring and treatment delivery 有权
    对比增强锥束X射线成像，评估，监测和治疗交付

    公开(公告)号：US20070269000A1

    公开(公告)日：2007-11-22

    申请号：US11437076

    申请日：2006-05-18

    Applicant: Larry Partain ,  Stavros Prionas ,  Edward Seppi ,  Robert Sutherland ,  David Humber ,  Hassan Mostafavi ,  Felix Fernando ,  John Boone

    Inventor： Larry Partain ,  Stavros Prionas ,  Edward Seppi ,  Robert Sutherland ,  David Humber ,  Hassan Mostafavi ,  Felix Fernando ,  John Boone

    IPC: A61B6/04

    CPC classification number: A61B6/4241 ,  A61B6/032 ,  A61B6/4085 ,  A61B6/482 ,  A61B6/502 ,  A61B6/507

    Abstract: A method of imaging a patient's uncompressed region of interest using X-ray cone beam computed tomography or cone beam digital tomography comprises the step of introducing an effective amount of a contrast agent to the uncompressed region of interest. A system for imaging a patient's uncompressed region of interest using cone beam computed tomography (CBCT) or cone beam digital tomography (CBDT) comprises an X-ray source transmitting an X-ray to the uncompressed region of interest, an image acquisition system acquiring a plurality of two-dimensional projection images data for a CBCT or CBDT data set with at least one of the projection images acquired in 35 milliseconds or less, and a processor generating a three-dimensional computed tomography image data set resolving voxels with dimensions of 0.4 mm or less in at least two orthogonal directions.

    Abstract translation: 使用X射线锥束计算机断层摄影或锥束数字断层摄影术对患者未压缩感兴趣区域成像的方法包括将有效量的造影剂引入未压缩感兴趣区域的步骤。 使用锥形束计算机断层摄影（CBCT）或锥束数字断层摄影（CBDT）对患者未压缩感兴趣区域成像的系统包括将X射线发射到感兴趣的未压缩区域的X射线源，获取 多个用于CBCT或CBDT数据集的二维投影图像数据，其具有在35毫秒或更短时间内获取的至少一个投影图像，以及处理器，其生成尺寸为0.4mm的三维计算机断层摄影图像数据集 或至少两个正交方向。

    System and method for imaging and treatment of tumorous tissue in breasts using computed tomography and radiotherapy
    3.
    发明申请
    System and method for imaging and treatment of tumorous tissue in breasts using computed tomography and radiotherapy 有权
    使用计算机断层扫描和放射治疗乳腺肿瘤组织成像和治疗的系统和方法

    公开(公告)号：US20060262898A1

    公开(公告)日：2006-11-23

    申请号：US11134695

    申请日：2005-05-20

    Applicant: Larry Partain ,  David Humber

    Inventor： Larry Partain ,  David Humber

    IPC: A61B6/04

    CPC classification number: A61B6/482 ,  A61B6/032 ,  A61B6/0414 ,  A61B6/107 ,  A61B6/405 ,  A61B6/4441 ,  A61B6/466 ,  A61B6/502 ,  A61B6/541 ,  A61N5/10 ,  A61N5/1081 ,  A61N2005/1097

    Abstract: The present invention provides a system 10 for irradiating a breast 20 of a patient 22. The system 10 comprises a gantry 12 rotatable about a horizontal axis 14 and comprising a radiation source 16 for generating a radiation beam 18 and a detector 24 spaced from the radiation source 16, and a barrier 26 disposed between the patient 22 and the gantry 12. The barrier 26 is provided with an opening 30 adapted to allow a breast 20 passing therethrough to be exposed to the radiation beam 18. In some embodiments, the barrier 26 is provided with an opening 30 adapted to allow both the breast 20 and the tissue leading from the breast to axilla and the muscle tissue of the adjacent chest wall passing therethrough to be exposed to the radiation beam 18.

    Abstract translation: 本发明提供一种用于照射患者22的乳房20的系统10。 系统10包括可围绕水平轴线14旋转并且包括用于产生辐射束18的辐射源16和与辐射源16间隔开的检测器24的台架12以及设置在患者22和台架12之间的阻挡层26。 屏障26设置有适于允许穿过其中的乳房20暴露于辐射束18的开口30。 在一些实施例中，屏障26设置有开口30，开口30适于允许乳房20和从乳房到达腋窝的组织和穿过其中的相邻胸壁的肌肉组织暴露于辐射束18。

    Methods, apparatus, and computer-program products for increasing accuracy in cone-beam computed tomography
    4.
    发明授权
    Methods, apparatus, and computer-program products for increasing accuracy in cone-beam computed tomography 有权
    方法，装置和计算机程序产品，用于提高锥束计算机断层扫描的精度

    公开(公告)号：US08320518B2

    公开(公告)日：2012-11-27

    申请号：US13209323

    申请日：2011-08-12

    Applicant: Larry Partain

    Inventor： Larry Partain

    IPC: A61B6/03 ,  H05G1/64 ,  G21K1/04

    CPC classification number: A61B6/032 ,  A61B6/035 ,  A61B6/06 ,  A61B6/4085 ,  G21K1/043 ,  G21K1/046

    Abstract: Portions of the radiation source are obscured so that the radiation only passes through the specific areas of the patient related to the regions-of-interest to the doctor. Scattered radiation received by detector pixels that are obscured by direct-line of sight radiation are used to estimate the scattered radiation in the un-obscured portion, which can be used to increase the accuracy of the image taken through the un-obscured portion.

    Abstract translation: 辐射源的一部分被遮蔽，使得辐射仅通过患者的与感兴趣区域相关的特定区域到医生。 被直接视线辐射遮蔽的检测器像素所接收到的散射辐射被用于估计未遮蔽部分中的散射辐射，其可用于增加通过未遮蔽部分拍摄的图像的精度。

    Breathing synchronized computed tomography image acquisition
    7.
    发明授权
    Breathing synchronized computed tomography image acquisition 有权
    呼吸同步计算机断层摄影图像采集

    公开(公告)号：US07177386B2

    公开(公告)日：2007-02-13

    申请号：US10801947

    申请日：2004-03-15

    Applicant: Hassan Mostafavi ,  Edward J. Seppi ,  Larry Partain

    Inventor： Hassan Mostafavi ,  Edward J. Seppi ,  Larry Partain

    IPC: H05G1/00

    CPC classification number: A61B6/032 ,  A61B5/1135 ,  A61B5/7289 ,  A61B6/4441 ,  A61B6/541

    Abstract: A method for collecting computed tomography (CT) image data includes determining a number of intervals N into which a respiratory cycle is to be divided, determining a number of respiratory cycles M to be covered in one gantry rotation, and rotating a gantry to collect at least M×N sets of CT image data of at least a portion of a patient, wherein each set of the CT image data corresponds to a phase of a respiratory cycle.

    Abstract translation: 收集计算机断层摄影（CT）图像数据的方法包括确定要分割呼吸周期的间隔N的数量，确定在一台架旋转中要覆盖的呼吸周期M的数量，以及旋转台架以收集 至少一部分患者的至少M×N组CT图像数据组，其中每组CT图像数据对应于呼吸周期的相位。

    Megavoltage imaging with a photoconductor based sensor
    8.
    发明申请
    Megavoltage imaging with a photoconductor based sensor 有权
    用基于感光体的传感器进行Megavoltage成像

    公开(公告)号：US20070023853A1

    公开(公告)日：2007-02-01

    申请号：US11193162

    申请日：2005-07-29

    Applicant: Larry Partain ,  George Zentai

    Inventor： Larry Partain ,  George Zentai

    IPC: H01L31/00

    CPC classification number: G01T1/24

    Abstract: A photodetector for detecting megavoltage (MV) radiation comprises a semiconductor conversion layer having a first surface and a second surface disposed opposite the first surface, a first electrode coupled to the first surface, a second electrode coupled to the second surface, and a low density substrate including a detector array coupled to the second electrode opposite the semiconductor conversion layer. The photodetector includes a sufficient thickness of a high density material to create a sufficient number of photoelectrons from incident MV radiation, so that the photoelectrons can be received by the conversion layer and converted to a sufficient of recharge carriers for detection by the detector array.

    Abstract translation: 用于检测兆伏特（MV）辐射的光电检测器包括半导体转换层，其具有与第一表面相对布置的第一表面和第二表面，耦合到第一表面的第一电极，耦合到第二表面的第二电极和低密度 衬底，包括耦合到与半导体转换层相对的第二电极的检测器阵列。 光电检测器包括足够厚度的高密度材料以从入射的MV辐射产生足够数量的光电子，使得光电子能够被转换层接收并转换成足够的再充电载体，以便由检测器阵列检测。

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