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1.发明申请NOVEL BIAROMATIC COMPOUNDS THAT MODULATE PPARy TYPE RECEPTORS AND COSMETIC/PHARMACEUTICAL COMPOSITIONS COMPRISED THEREOF 失效调节PPARY型受体和包含其的化妆品/药物组合物的新型双组分化合物公开(公告)号：US20120121527A1
公开(公告)日：2012-05-17
申请号：US13353125
申请日：2012-01-18
IPC分类号： A61K31/381 , A61K8/49 , C07D307/52 , A61K31/341 , C07D213/53 , A61K31/44 , C07D239/24 , A61K31/505 , A61Q5/00 , A61Q19/00 , A61P17/00 , A61P3/04 , A61P3/10 , A61P29/00 , A61P35/00 , A61P37/00 , A61P9/10 , A61P9/12 , C07D333/22
CPC分类号： C07D333/24 , C07D213/55 , C07D213/75 , C07D239/26 , C07D239/42 , C07D307/54
摘要： Novel biaromatic compounds having the general formula (I): and cosmetic/pharmaceutical compositions comprised thereof are useful in human or veterinary medicine (in dermatology and also in the fields of cardiovascular diseases, of immune diseases and/of diseases related to the metabolism of lipids), or, alternatively, in cosmetic compositions.
摘要翻译： 具有通式（I）的新型双芳族化合物及其包含的化妆品/药物组合物可用于人或兽医学（在皮肤病学领域以及心血管疾病，免疫疾病和/或与脂质代谢有关的疾病领域 ），或者在化妆品组合物中。
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2.发明授权Biaromatic compounds that modulate PPARgamma type receptors and cosmetic/pharmaceutical compositions comprised thereof 失效调节PPARγ型受体的双芳族化合物和由其组成的化妆品/药物组合物公开(公告)号：US08129416B2
公开(公告)日：2012-03-06
申请号：US11802234
申请日：2007-05-21
IPC分类号： C07D333/38 , A61K31/381
CPC分类号： C07D333/24 , C07D213/55 , C07D213/75 , C07D239/26 , C07D239/42 , C07D307/54
摘要： Novel biaromatic compounds having the general formula (I): and cosmetic/pharmaceutical compositions comprised thereof are useful in human or veterinary medicine (in dermatology and also in the fields of cardiovascular diseases, of immune diseases and/of diseases related to the metabolism of lipids), or, alternatively, in cosmetic compositions.
摘要翻译： 具有通式（I）的新型双芳族化合物及其包含的化妆品/药物组合物可用于人或兽医学（在皮肤病学领域以及心血管疾病，免疫疾病和/或与脂质代谢有关的疾病领域 ），或者在化妆品组合物中。
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3.发明授权Biaromatic compound activators of PPARγ receptors and cosmetic/pharmaceutical compositions comprised thereof 失效PPARγ受体的双芳族化合物活化剂和由它们组成的美容/药物组合物公开(公告)号：US07863332B2
公开(公告)日：2011-01-04
申请号：US11707123
申请日：2007-02-16
IPC分类号： A61K31/17 , A61K31/24 , C07C275/28 , C07C275/40 , C07C275/42 , C07C229/42 , C07C229/44 , C07C335/16 , C07C335/20
CPC分类号： C07D295/088 , C07C275/42 , C07C335/22 , C07C2601/02 , C07D213/75 , C07D295/32
摘要： Novel biaromatic compounds having the general formula (I): and cosmetic/pharmaceutical compositions comprised thereof are useful in human or veterinary medicine (in dermatology and also in the fields of cardiovascular diseases, of immune diseases and/or of diseases related to the metabolism of lipids) or, alternatively, in cosmetic compositions.
摘要翻译： 具有通式（I）的新型双芳族化合物及其包含的化妆品/药物组合物可用于人或兽医学（在皮肤病学领域以及心血管疾病领域的免疫疾病和/或与代谢有关的疾病 脂质），或者在化妆品组合物中。
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4.发明授权Biaromatic compounds that modulate PPARy type receptors and cosmetic/pharmaceutical compositions comprised thereof 失效调节PPARγ型受体的双芳族化合物和由其组成的化妆品/药物组合物公开(公告)号：US08513297B2
公开(公告)日：2013-08-20
申请号：US13353125
申请日：2012-01-18
IPC分类号： C07D333/24 , A61K31/381
CPC分类号： C07D333/24 , C07D213/55 , C07D213/75 , C07D239/26 , C07D239/42 , C07D307/54
摘要： Novel biaromatic compounds having the general formula (I): and cosmetic/pharmaceutical compositions comprised thereof are useful in human or veterinary medicine (in dermatology and also in the fields of cardiovascular diseases, of immune diseases and/of diseases related to the metabolism of lipids), or, alternatively, in cosmetic compositions.
摘要翻译： 具有通式（I）的新型双芳族化合物及其包含的化妆品/药物组合物可用于人或兽医学（在皮肤病学领域以及心血管疾病，免疫疾病和/或与脂质代谢有关的疾病领域 ），或者在化妆品组合物中。
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5.发明申请NOVEL 4-HETEROARYLIMIDAZOLE-2-THIONE TYROSINASE INHIBITORS AND PHARMACEUTICAL/COSMETIC APPLICATIONS THEREOF 失效新型4-杂环二咪唑-2-硫酸酯酶抑制剂及其药物/化妆品应用公开(公告)号：US20100144813A1
公开(公告)日：2010-06-10
申请号：US12631309
申请日：2009-12-04
IPC分类号： A61K31/4178 , C07D233/10 , A61P17/02 , A61P37/08
CPC分类号： C07D405/04 , C07D409/04 , C07D417/04
摘要： Novel 4-heteroarylimidazole-2-thione tyrosinase inhibiting compounds corresponding to the following general formula (I): formulated into pharmaceutical or cosmetic compositions are useful for the treatment or prevention of pigmentary disorders, or for preventing and/or treating signs of skin aging, and/or for body or hair hygiene.
摘要翻译： 对应于以下通式（I）的新型4-杂芳基咪唑-2-硫酮酪氨酸酶抑制化合物：配制成药物或化妆品组合物可用于治疗或预防色素障碍，或用于预防和/或治疗皮肤老化迹象， 和/或用于身体或头发卫生。
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6.发明申请NOVEL 4-PHENYLIMIDAZOLE-2-THIONE TYROSINASE INHIBITORS AND PHARMACEUTICAL/COSMETIC APPLICATIONS THEREOF 失效新型4-苯基咪唑二酮-2-酪氨酸酶抑制剂及其药物/化妆品应用公开(公告)号：US20100144814A1
公开(公告)日：2010-06-10
申请号：US12631392
申请日：2009-12-04
IPC分类号： A61K31/4164 , C07D233/84
CPC分类号： C07D233/84 , A61K8/4946 , A61K2800/782 , A61Q19/004 , A61Q19/02 , A61Q19/08 , C07D405/10 , C07D407/10 , C07D413/10
摘要： Novel 4-phenylimidazole-2-thione tyrosinase inhibiting compounds corresponding to the following general formula (I): formulated into pharmaceutical or cosmetic compositions are useful for the treatment or prevention of pigmentary disorders, or for preventing and/or treating signs of skin aging, and/or for body or hair hygiene.
摘要翻译： 对应于以下通式（I）的新型4-苯基咪唑-2-硫酮酪氨酸酶抑制化合物：配制成药物或化妆品组合物可用于治疗或预防色素障碍，或用于预防和/或治疗皮肤老化迹象， 和/或用于身体或头发卫生。
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7.发明授权4-(azacycloalkyl)benzene-1,3-diol compounds as tyrosinase inhibitors, process for the preparation thereof and use thereof in human medicine and in cosmetics 有权4-（氮杂环烷基）苯-1,3-二醇化合物作为酪氨酸酶抑制剂，其制备方法及其在人类药物和化妆品中的应用公开(公告)号：US08299259B2
公开(公告)日：2012-10-30
申请号：US13131363
申请日：2009-12-02
IPC分类号： C07D211/06 , C07D295/00
CPC分类号： C07D401/12 , A61K9/06 , C07D205/04 , C07D207/08 , C07D207/16 , C07D211/22 , C07D211/26 , C07D211/60
摘要： 4-(azacycloalkyl)benzene-1,3-diol compounds are described corresponding to general formula (I) below: Also described, are compositions including the same, processes for preparation thereof and uses thereof in pharmaceutical or cosmetic compositions to treat pigmentary disorders.
摘要翻译： 4-（氮杂环烷基）苯-1,3-二醇化合物对应于下列通式（I）描述：还描述了包含它们的组合物，其制备方法及其在药物或化妆品组合物中用于治疗色素障碍的用途。
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8.发明授权4-phenylimidazole-2-thione tyrosinase inhibitors and pharmaceutical/cosmetic applications thereof 失效4-苯基咪唑-2-硫酮酪氨酸酶抑制剂及其药物/化妆品应用公开(公告)号：US08119674B2
公开(公告)日：2012-02-21
申请号：US12631392
申请日：2009-12-04
IPC分类号： A61K31/4164 , C07D233/42
CPC分类号： C07D233/84 , A61K8/4946 , A61K2800/782 , A61Q19/004 , A61Q19/02 , A61Q19/08 , C07D405/10 , C07D407/10 , C07D413/10
摘要： Novel 4-phenylimidazole-2-thione tyrosinase inhibiting compounds corresponding to the following general formula (I): formulated into pharmaceutical or cosmetic compositions are useful for the treatment or prevention of pigmentary disorders, or for preventing and/or treating signs of skin aging, and/or for body or hair hygiene.
摘要翻译： 对应于以下通式（I）的新型4-苯基咪唑-2-硫酮酪氨酸酶抑制化合物：配制成药物或化妆品组合物可用于治疗或预防色素障碍，或用于预防和/或治疗皮肤老化迹象， 和/或用于身体或头发卫生。
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9.发明授权4-(azacycloalkyl)benzene-1,3-diol compounds as tyrosinase inhibitors, process for the preparation thereof and use thereof in human medicine and in cosmetics 有权4-（氮杂环烷基）苯-1,3-二醇化合物作为酪氨酸酶抑制剂，其制备方法及其在人类药物和化妆品中的应用公开(公告)号：US08697726B2
公开(公告)日：2014-04-15
申请号：US13611546
申请日：2012-09-12
IPC分类号： A61K31/445
CPC分类号： C07D401/12 , A61K9/06 , C07D205/04 , C07D207/08 , C07D207/16 , C07D211/22 , C07D211/26 , C07D211/60
摘要： 4-(azacycloalkyl)benzene-1,3-diol compounds are described corresponding to general formula (I) below: Also described, are compositions including the same, processes for preparation thereof and uses thereof in pharmaceutical or cosmetic compositions to treat pigmentary disorders.
摘要翻译： 4-（氮杂环烷基）苯-1,3-二醇化合物对应于下列通式（I）描述：还描述了包含它们的组合物，其制备方法及其在药物或化妆品组合物中用于治疗色素障碍的用途。
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10.发明申请NOVEL 4-(AZACYCLOALKYL)BENZENE-1,3-DIOL COMPOUNDS AS TYROSINASE INHIBITORS, PROCESS FOR THE PREPARATION THEREOF AND USE THEREOF IN HUMAN MEDICINE AND IN COSMETICS 有权新型4-（氮杂环丁基）苯甲-1,3-二醇化合物作为酪氨酸酶抑制剂，其制备方法及其在人体药物和化妆品中的应用公开(公告)号：US20110311466A1
公开(公告)日：2011-12-22
申请号：US13131363
申请日：2009-12-02
IPC分类号： A61K31/397 , C07D207/08 , C07D211/60 , A61K31/40 , A61Q19/02 , A61P17/00 , A61P17/02 , A61P37/08 , A61K8/49 , C07D205/04 , A61K31/451
CPC分类号： C07D401/12 , A61K9/06 , C07D205/04 , C07D207/08 , C07D207/16 , C07D211/22 , C07D211/26 , C07D211/60
摘要： 4-(azacycloalkyl)benzene-1,3-diol compounds are described corresponding to general formula (I) below: Also described, are compositions including the same, processes for preparation thereof and uses thereof in pharmaceutical or cosmetic compositions to treat pigmentary disorders.
摘要翻译： 4-（氮杂环烷基）苯-1,3-二醇化合物对应于下列通式（I）描述：还描述了包含它们的组合物，其制备方法及其在药物或化妆品组合物中用于治疗色素障碍的用途。
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