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公开(公告)号:US20120144512A1
公开(公告)日:2012-06-07
申请号:US13281158
申请日:2011-10-25
申请人: Lawren Wu , Mercedesz Balazs , Hans Brightbill , Andrew Chan , Yvonne Chen , Anan Chuntharapai , Mark Dennis , Terence Wong
发明人: Lawren Wu , Mercedesz Balazs , Hans Brightbill , Andrew Chan , Yvonne Chen , Anan Chuntharapai , Mark Dennis , Terence Wong
IPC分类号: A01K67/027
CPC分类号: C07K16/4291 , A01K67/0278 , A01K2217/072 , A01K2227/105 , A01K2267/0387 , A61K2039/505 , C07K2317/21 , C07K2317/24 , C07K2317/41 , C07K2317/73
摘要: The present application relates to apoptotic anti-IgE antibodies, nucleic acid encoding the same, therapeutic compositions thereof, and their use in the treatment of IgE-mediated disorders.
摘要翻译: 本申请涉及凋亡性抗IgE抗体,编码它的核酸,其治疗组合物及其在治疗IgE介导的病症中的用途。
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公开(公告)号:US20120149881A1
公开(公告)日:2012-06-14
申请号:US13281126
申请日:2011-10-25
申请人: Lawren Wu , Mercedesz Balazs , Hans Brightbill , Andrew Chan , Yvonne Chen , Anan Chuntharapai , Mark Dennis , Terence Wong
发明人: Lawren Wu , Mercedesz Balazs , Hans Brightbill , Andrew Chan , Yvonne Chen , Anan Chuntharapai , Mark Dennis , Terence Wong
IPC分类号: C07K16/42
CPC分类号: C07K16/4291 , A01K67/0278 , A01K2217/072 , A01K2227/105 , A01K2267/0387 , A61K2039/505 , C07K2317/21 , C07K2317/24 , C07K2317/41 , C07K2317/73
摘要: The present application relates to apoptotic anti-IgE antibodies, nucleic acid encoding the same, therapeutic compositions thereof, and their use in the treatment of IgE-mediated disorders.
摘要翻译: 本申请涉及凋亡性抗IgE抗体,编码它的核酸,其治疗组合物及其在治疗IgE介导的病症中的用途。
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公开(公告)号:US08632775B2
公开(公告)日:2014-01-21
申请号:US13281126
申请日:2011-10-25
申请人: Lawren Wu , Mercedesz Balazs , Hans Brightbill , Andrew Chan , Yvonne Chen , Anan Chuntharapai , Mark Dennis , Terence Wong
发明人: Lawren Wu , Mercedesz Balazs , Hans Brightbill , Andrew Chan , Yvonne Chen , Anan Chuntharapai , Mark Dennis , Terence Wong
IPC分类号: A61K39/00
CPC分类号: C07K16/4291 , A01K67/0278 , A01K2217/072 , A01K2227/105 , A01K2267/0387 , A61K2039/505 , C07K2317/21 , C07K2317/24 , C07K2317/41 , C07K2317/73
摘要: The present application relates to apoptotic anti-IgE antibodies, nucleic acid encoding the same, therapeutic compositions thereof, and their use in the treatment of IgE-mediated disorders.
摘要翻译: 本申请涉及凋亡性抗IgE抗体,编码它的核酸,其治疗组合物及其在治疗IgE介导的病症中的用途。
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公开(公告)号:US08071097B2
公开(公告)日:2011-12-06
申请号:US12053063
申请日:2008-03-21
申请人: Lawren Wu , Mercedesz Balazs , Hans Brightbill , Andrew Chan , Yvonne Chen , Anan Chuntharapai , Mark Dennis , Terence Wong
发明人: Lawren Wu , Mercedesz Balazs , Hans Brightbill , Andrew Chan , Yvonne Chen , Anan Chuntharapai , Mark Dennis , Terence Wong
IPC分类号: A61K39/395
CPC分类号: C07K16/4291 , A01K67/0278 , A01K2217/072 , A01K2227/105 , A01K2267/0387 , A61K2039/505 , C07K2317/21 , C07K2317/24 , C07K2317/41 , C07K2317/73
摘要: The present application relates to apoptotic anti-IgE antibodies, nucleic acid encoding the same, therapeutic compositions thereof, and their use in the treatment of IgE-mediated disorders.
摘要翻译: 本申请涉及凋亡性抗IgE抗体,编码它的核酸,其治疗组合物及其在治疗IgE介导的病症中的用途。
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公开(公告)号:US20120178127A1
公开(公告)日:2012-07-12
申请号:US13281224
申请日:2011-10-25
申请人: Lawren Wu , Mercedesz Balazs , Hans Brightbill , Andrew Chan , Yvonne Chen , Anan Chuntharapai , Mark Dennis , Terence Wong
发明人: Lawren Wu , Mercedesz Balazs , Hans Brightbill , Andrew Chan , Yvonne Chen , Anan Chuntharapai , Mark Dennis , Terence Wong
CPC分类号: C07K16/4291 , A01K67/0278 , A01K2217/072 , A01K2227/105 , A01K2267/0387 , A61K2039/505 , C07K2317/21 , C07K2317/24 , C07K2317/41 , C07K2317/73
摘要: The present application relates to apoptotic anti-IgE antibodies, nucleic acid encoding the same, therapeutic compositions thereof, and their use in the treatment of IgE-mediated disorders.
摘要翻译: 本申请涉及凋亡性抗IgE抗体,编码它的核酸,其治疗组合物及其在治疗IgE介导的病症中的用途。
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公开(公告)号:US20090010924A1
公开(公告)日:2009-01-08
申请号:US12053063
申请日:2008-03-21
申请人: Lawren Wu , Mercedesz Balazs , Hans Brightbill , Andrew Chan , Yvonne Chen , Anan Chuntharapai , Mark Dennis , Terence Wong
发明人: Lawren Wu , Mercedesz Balazs , Hans Brightbill , Andrew Chan , Yvonne Chen , Anan Chuntharapai , Mark Dennis , Terence Wong
IPC分类号: A61K39/395 , C07K16/42 , C07K16/00 , C12N15/63 , C12P21/04 , A01K67/00 , C12N5/00 , C12N5/10 , C07H21/04 , C07K7/08
CPC分类号: C07K16/4291 , A01K67/0278 , A01K2217/072 , A01K2227/105 , A01K2267/0387 , A61K2039/505 , C07K2317/21 , C07K2317/24 , C07K2317/41 , C07K2317/73
摘要: The present application relates to apoptotic anti-IgE antibodies, nucleic acid encoding the same, therapeutic compositions thereof, and their use in the treatment of IgE-mediated disorders.
摘要翻译: 本申请涉及凋亡性抗IgE抗体,编码它的核酸,其治疗组合物及其在治疗IgE介导的病症中的用途。
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公开(公告)号:US08586040B2
公开(公告)日:2013-11-19
申请号:US13281209
申请日:2011-10-25
申请人: Lawren Wu , Mercedesz Balazs , Hans Brightbill , Andy Chan , Yvonne Chen , Anan Chuntharapai , Mark Dennis , Terence Wong
发明人: Lawren Wu , Mercedesz Balazs , Hans Brightbill , Andy Chan , Yvonne Chen , Anan Chuntharapai , Mark Dennis , Terence Wong
IPC分类号: A61K39/00
CPC分类号: C07K16/4291 , A01K67/0278 , A01K2217/072 , A01K2227/105 , A01K2267/0387 , A61K2039/505 , C07K2317/21 , C07K2317/24 , C07K2317/41 , C07K2317/73
摘要: The present application relates to apoptotic anti-IgE antibodies, nucleic acid encoding the same, therapeutic compositions thereof, and their use in the treatment of IgE-mediated disorders.
摘要翻译: 本申请涉及凋亡性抗IgE抗体,编码它的核酸,其治疗组合物及其在治疗IgE介导的病症中的用途。
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公开(公告)号:US08618274B2
公开(公告)日:2013-12-31
申请号:US13281224
申请日:2011-10-25
申请人: Lawren Wu , Mercedesz Balazs , Hans Brightbill , Andy Chan , Yvonne Chen , Anan Chuntharapai , Mark Dennis , Terence Wong
发明人: Lawren Wu , Mercedesz Balazs , Hans Brightbill , Andy Chan , Yvonne Chen , Anan Chuntharapai , Mark Dennis , Terence Wong
IPC分类号: C07H21/04
CPC分类号: C07K16/4291 , A01K67/0278 , A01K2217/072 , A01K2227/105 , A01K2267/0387 , A61K2039/505 , C07K2317/21 , C07K2317/24 , C07K2317/41 , C07K2317/73
摘要: The present application relates to apoptotic anti-IgE antibodies, nucleic acid encoding the same, therapeutic compositions thereof, and their use in the treatment of IgE-mediated disorders.
摘要翻译: 本申请涉及凋亡性抗IgE抗体,编码它的核酸,其治疗组合物及其在治疗IgE介导的病症中的用途。
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9.COMPOSITIONS AND METHODS FOR THE TREATMENT OF DISEASES AND DISORDERS ASSOCIATED WITH CYTOKINE SIGNALING 有权
标题翻译: 治疗与细胞因子信号相关的疾病和疾病的组合物和方法公开(公告)号:US20070212356A1
公开(公告)日:2007-09-13
申请号:US11565395
申请日:2006-11-30
申请人: Yvonne Chen , Anan Chuntharapai , Dimitry Danilenko , Wenjun Ouyang , Susan Sa , Patricia Valdez , Terence Wong , Jianfeng Wu , Yan Zheng
发明人: Yvonne Chen , Anan Chuntharapai , Dimitry Danilenko , Wenjun Ouyang , Susan Sa , Patricia Valdez , Terence Wong , Jianfeng Wu , Yan Zheng
IPC分类号: A61K39/395 , C07K16/24
CPC分类号: A61K39/3955 , A61K38/17 , A61K38/1793 , A61K38/20 , A61K2039/505 , A61K2039/57 , C07K16/244 , C07K16/2866 , C07K2317/76 , C07K2317/92
摘要: Compositions and methods are provided for the diagnosis and treatment of inflammation and autoimmune disorders, such as psoriasis. Compositions and methods for modulating IL-23 or IL-22 signaling are provided.
摘要翻译: 提供了用于诊断和治疗炎症和自身免疫性疾病如牛皮癣的组合物和方法。 提供了调节IL-23或IL-22信号传导的组合物和方法。
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10.Compositions and methods for the treatment of diseases and disorders associated with cytokine signaling 有权
标题翻译: 用于治疗与细胞因子信号传导相关的疾病和病症的组合物和方法公开(公告)号:US07737259B2
公开(公告)日:2010-06-15
申请号:US11565395
申请日:2006-11-30
申请人: Yvonne M. Chen , Anan Chuntharapai , Dimitry Danilenko , Wenjun Ouyang , Susan Sa , Patricia Valdez , Terence Wong , Jianfeng Wu , Yan Zheng
发明人: Yvonne M. Chen , Anan Chuntharapai , Dimitry Danilenko , Wenjun Ouyang , Susan Sa , Patricia Valdez , Terence Wong , Jianfeng Wu , Yan Zheng
IPC分类号: C07K16/24
CPC分类号: A61K39/3955 , A61K38/17 , A61K38/1793 , A61K38/20 , A61K2039/505 , A61K2039/57 , C07K16/244 , C07K16/2866 , C07K2317/76 , C07K2317/92
摘要: Compositions and methods are provided for the diagnosis and treatment of inflammation and autoimmune disorders, such as psoriasis. Compositions and methods for modulating IL-23 or IL-22 signaling are provided.
摘要翻译: 提供了用于诊断和治疗炎症和自身免疫性疾病如牛皮癣的组合物和方法。 提供了调节IL-23或IL-22信号传导的组合物和方法。
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