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83 条记录 (耗时 0.046 秒)

    Substituted pyridine herbicides
    4.
    发明授权
    Substituted pyridine herbicides 失效
    取代吡啶除草剂

    公开(公告)号：US5196045A

    公开(公告)日：1993-03-23

    申请号：US672231

    申请日：1991-03-20

    申请人： Len F. Lee ,  Mark G. Dolson

    发明人： Len F. Lee ,  Mark G. Dolson

    IPC分类号： A01N43/40 ,  A01N43/713 ,  A01N47/18 ,  A01N47/38 ,  A01N57/24 ,  C07D213/80 ,  C07D213/83 ,  C07D401/04 ,  C07F9/58

    CPC分类号： C07D213/80 ,  A01N43/40 ,  A01N43/713 ,  A01N47/18 ,  A01N47/38 ,  A01N57/24 ,  C07D213/83 ,  C07D401/04 ,  C07F9/588

    摘要： A compound having the structural formula ##STR1## wherein: Y is selected from O and S;R.sub.1 and R.sub.4 are independently selected from fluorinated methyl, chlorofluorinated methyl, and C.sub.1 -C.sub.4 alkyl, provided that not both R.sub.1 and R.sub.4 may be C.sub.1 -C.sub.4 alkyl;R.sub.2 is selected from hydrogen, lower alkyl, haloalkyl, alkenyl, alkynyl, haloalkenyl, and a cation;R.sub.3 is selected from C.sub.1 -C.sub.5 alkyl, cycloalkyl, cycloalkylalkyl, hydroxy, and alkoxy; andX is selected from ##STR2## in which R.sub.8 is selected from H, alkyl and CF.sub.3 and R.sub.10 is selected from F, Cl, --OR.sup.1, --SR.sup.1, --NHR.sup.1, --N(R.sup.1).sub.2, phenyl, substituted phenyl, and --P(OR.sup.1).sub.2 where R.sup.1 is as defined above; ##STR3## wherein R.sup.1 is as defined above; ##STR4## wherein R.sub.14 and R.sub.15 are independently selected from hydrogen and alkyl; and --N.dbd.C.dbd.O and their use as herbicides.

    摘要翻译： 具有结构式的化合物，其中：Y选自O和S; R1和R4独立地选自氟化甲基，氯氟化甲基和C 1 -C 4烷基，条件是不是R1和R4都可以是C1-C4烷基; R2选自氢，低级烷基，卤代烷基，烯基，炔基，卤代烯基和阳离子; R3选自C1-C5烷基，环烷基，环烷基烷基，羟基和烷氧基; 并且X选自其中R 8选自H，烷基和CF 3且R 10选自F，Cl，-OR 1，-SR 1，-NHR 1，-N（R 1）2，苯基，取代的苯基和 -P（OR1）2其中R1如上所定义; 国家统计局 NO2; 其中R1如上所定义; 其中R 14和R 15独立地选自氢和烷基; 和-N = C = O及其作为除草剂的用途。

    3,4-Diaryl substituted pyridines for the treatment of inflammation
    7.
    发明授权
    3,4-Diaryl substituted pyridines for the treatment of inflammation 失效
    3,4-二芳基取代的吡啶用于治疗炎症

    公开(公告)号：US5596008A

    公开(公告)日：1997-01-21

    申请号：US386843

    申请日：1995-02-10

    申请人： Len F. Lee

    发明人： Len F. Lee

    IPC分类号： C07D213/61 ,  C07D213/64 ,  C07D213/34 ,  A61K31/44

    CPC分类号： C07D213/64 ,  C07D213/61

    摘要： A class of substitute pyridyl compounds is described for use in treating inflammation and inflammation-related disorders. Compounds of particular interest are defined by Formula I ##STR1## wherein R.sup.1 is haloalkyl; wherein R.sup.2 is aryl optionally substituted at a substitutable position with one or more radicals independently selected from alkylsulfinyl, alkyl, cyano, carboxyl, alkoxycarbonyl, haloalkyl, hydroxyl, hydroxyalkyl, haloalkoxy, amino, alkylamino, arylamino, nitro, halo, alkoxy and alkylthio; wherein R.sup.3 is aryl substituted at a substitutable position with a radical selected from alkylsulfonyl and sulfamyl; and wherein R.sup.4 is selected from halo, alkoxy and alkynyloxy; or a pharmaceutically-acceptable salt thereof.

    摘要翻译： 描述了一类替代吡啶基化合物用于治疗炎症和炎症相关疾病。 特别感兴趣的化合物由式I（I）定义，其中R 1是卤代烷基; 其中R2是任选在可取代的位置被一个或多个独立地选自烷基亚磺酰基，烷基，氰基，羧基，烷氧基羰基，卤代烷基，羟基，羟基烷基，卤代烷氧基，氨基，烷基氨基，芳基氨基，硝基，卤素，烷氧基和烷硫基的基团取代的芳基。 其中R3是在可取代的位置被选自烷基磺酰基和氨磺酰基的基团取代的芳基; 并且其中R 4选自卤素，烷氧基和炔氧基; 或其药学上可接受的盐。