公开(公告)号：US10792394B2

公开(公告)日：2020-10-06

申请号：US15606924

申请日：2017-05-26

申请人： LifeCell Corporation

发明人： Ming F. Pomerleau ,  Hua Wan ,  Hui Xu ,  Dennis Y. Lee

IPC分类号： A61L27/36 ,  A61K38/39

摘要： Methods for treating tissue matrices and tissue matrices produced according to the methods are provided. The methods can include treating select portions of a tissue matrix with a fluid containing at least one agent to produce a tissue matrix with variable mechanical and/or biological properties.

公开(公告)号：US20190117202A1

公开(公告)日：2019-04-25

申请号：US15772601

申请日：2016-11-01

申请人： LifeCell Corporation

发明人： Kai-Roy Wang ,  Christopher Locke ,  Dennis Y. Lee ,  Evan J. Friedman ,  Israel Jessop ,  Sangwook Park

IPC分类号： A61B10/02 ,  A61M5/142

摘要： Devices, systems, and methods for tissue transfer are disclosed that can allow control of transfer speed. The devices use positive and negative pressure to advance a plunger (322) into or out of a body (311) of the device. A pressure regulator may be used to control the applied pressure. Maintaining transfer speed within acceptable ranges and/or controlling pressure or shear forces on tissues can improve the viability of certain types of tissue.

公开(公告)号：US20180098836A1

公开(公告)日：2018-04-12

申请号：US15724616

申请日：2017-10-04

申请人： LifeCell Corporation

发明人： Dennis Y. Lee ,  Jennifer Lynn Steinkoenig ,  Israel James Jessop ,  Alexander Ringo

IPC分类号： A61F2/00

CPC分类号： A61F2/0077 ,  A61F2/0063 ,  A61F2002/0068 ,  A61F2002/0081 ,  A61L27/362 ,  A61L27/3633 ,  A61L27/50 ,  A61L27/60 ,  A61L2430/34 ,  A61L2430/40

摘要： The present disclosure relates to tissue matrix products. The products can include tissue matrices that have openings such as holes or perforations located at certain positions to improve various functions without substantial loss of strength or other important properties. The openings can facilitate implantation of the tissue matrices in surgical procedures thereby speeding operation times and potentially improving surgical results.

公开(公告)号：US20200315776A1

公开(公告)日：2020-10-08

申请号：US16842162

申请日：2020-04-07

申请人： LifeCell Corporation

发明人： Dennis Y. Lee

IPC分类号： A61F2/12 ,  A61L27/36

摘要： The present disclosure provides anchor bolsters for three-dimensional biologic scaffolds, including related methods of formation and use. The composite bolster-scaffold provides an improved device to securely anchor a three-dimensional tissue scaffold in position relative to surrounding anatomic structures, allowing time for colonization of native cells and subsequent incorporation of the three-dimensional tissue scaffold by the recipient tissue bed.

公开(公告)号：US20170348460A1

公开(公告)日：2017-12-07

申请号：US15606924

申请日：2017-05-26

申请人： LifeCell Corporation

发明人： Ming Fang ,  Hua Wan ,  Hui Xu ,  Dennis Y. Lee

IPC分类号： A61L27/36 ,  A61L27/54 ,  A61L31/16 ,  A61K35/35 ,  A61K38/39

摘要： Methods for treating tissue matrices and tissue matrices produced according to the methods are provided. The methods can include treating select portions of a tissue matrix with a fluid containing at least one agent to produce a tissue matrix with variable mechanical and/or biological properties