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1.发明授权4-Phenyl-4-(N-(phenyl)amido) piperidine derivatives and pharmaceutical compositions and method employing such compounds 失效4-苯基-4-（N-（苯基）酰氨基）哌啶衍生物和使用这些化合物的药物组合物和方法
公开(公告)号：US4921864A
公开(公告)日：1990-05-01
申请号：US255180
申请日：1988-10-07
IPC分类号： C07D211/58 , C07D211/72 , C07D401/06 , C07D409/06 , C07D413/06 , C07D417/06
CPC分类号： C07D401/06 , C07D211/58 , C07D211/72 , C07D409/06 , C07D413/06 , C07D417/06
摘要： Compounds are disclosed of the formula ##STR1## where R.sup.2 is unsubstituted or substituted phenyl, R.sup.3 is lower alkyl, lower cycloalkyl or lower alkoxy lower alkyl, and L is selected from a wide variety of groups. This new class of compounds exhibit improved analgesic and anesthetic properties.
摘要翻译： 公开了下式的化合物：其中R 2为未取代或取代的苯基，R 3为低级烷基，低级环烷基或低级烷氧基低级烷基，L选自多种基团。 这种新型化合物具有改善的止痛和麻醉性能。
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2.发明授权4-phenyl-4-[N-(phenyl)amido]piperidine compounds and pharmaceutical compositions employing such compounds 失效4-苯基-4- [N-（苯基）酰氨基]哌啶化合物和采用这些化合物的药物组合物
公开(公告)号：US4957929A
公开(公告)日：1990-09-18
申请号：US440933
申请日：1988-11-22
IPC分类号： C07D211/58 , C07D211/72 , C07D401/06 , C07D409/06 , C07D413/06 , C07D417/06
CPC分类号： C07D401/06 , C07D211/58 , C07D211/72 , C07D409/06 , C07D413/06 , C07D417/06
摘要： Compounds are disclosed of the formula ##STR1## where R.sup.2 is unsubstituted or substituted phenyl, R.sup.3 is lower alkyl, lower cycloalkyl or lower alkoxy lower alkyl, and L is selected from a wide variety of groups. This new class of compounds exhibit improved analgesic and anesthetic properties.
摘要翻译： 公开了下式的化合物：其中R 2为未取代或取代的苯基，R 3为低级烷基，低级环烷基或低级烷氧基低级烷基，L选自多种基团。 这种新型化合物具有改善的止痛和麻醉性能。
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3.发明授权4-phenyl-4-(N-(phenyl)amido) piperidine derivatives and pharmaceutical compositions and method employing such compounds 失效4-苯基-4-（N-（苯基）酰氨基）哌啶衍生物和使用这些化合物的药物组合物和方法
公开(公告)号：US4791121A
公开(公告)日：1988-12-13
申请号：US115284
申请日：1987-11-02
IPC分类号： C07D211/26 , A61K31/4427 , A61K31/4433 , A61K31/445 , A61K31/4465 , A61K31/4468 , A61K31/451 , A61P23/02 , A61P25/02 , A61P25/04 , C07D211/58 , C07D211/72 , C07D401/06 , C07D409/06 , C07D413/04 , C07D413/06 , C07D417/06
CPC分类号： C07D401/06 , C07D211/58 , C07D211/72 , C07D409/06 , C07D413/06 , C07D417/06
摘要： Compounds are disclosed of the formula ##STR1## where R.sup.2 is unsubstituted or substituted phenyl, R.sup.3 is lower alkyl, lower cycloalkyl or lower alkoxy lower alkyl, and L is selected from a wide variety of groups. This new class of compounds exhibit improved analgesic and anesthetic properties.
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4.发明授权4-phenyl-4-N-(phenyl) amido piperidine derivatives and pharmaceutical compositions and method employing such compounds 失效4-苯基-4-N-（苯基）酰氨基哌啶衍生物和使用这些化合物的药物组合物和方法
公开(公告)号：US5013742A
公开(公告)日：1991-05-07
申请号：US543249
申请日：1990-06-25
IPC分类号： C07D211/58 , C07D211/72 , C07D401/06 , C07D409/06 , C07D413/06 , C07D417/06
CPC分类号： C07D401/06 , C07D211/58 , C07D211/72 , C07D409/06 , C07D413/06 , C07D417/06
摘要： Compounds are disclosed of the formula ##STR1## where R.sup.2 is unsubstituted or substituted phenyl, R.sup.3 is lower alkyl, lower cycloalkyl or lower alkoxy lower alkyl, and L is selected from a wide variety of groups. This new class of compounds exhibit improved analgesic and anesthetic properties.
摘要翻译： 公开了下式的化合物：其中R 2为未取代或取代的苯基，R 3为低级烷基，低级环烷基或低级烷氧基低级烷基，L选自多种基团。 这种新型化合物具有改善的止痛和麻醉性能。
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5.发明授权Stereoselective preparation of 3-substituted-4-piperidine compounds and derivatives 失效3-取代-4-哌啶化合物及其衍生物的立体选择性制备
公开(公告)号：US4849521A
公开(公告)日：1989-07-18
申请号：US115276
申请日：1987-11-02
IPC分类号： C07B53/00 , C07D211/58 , C07D211/72 , C07D417/06
CPC分类号： C07D211/58
摘要： The present invention is directed to an improved stereoselective tandem substitution and reduction of an imine precursor to the cis form of 3-substituted-4-(phenylanilo)piperidine compounds or their substituted derivatives.
摘要翻译： 本发明涉及改进的立体选择性串联取代和亚胺前体还原为3-取代-4-（苯基苯胺基）哌啶化合物或其取代衍生物的顺式形式。
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