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    Nuclear magnetic resonance systems and methods for noninvasive and in-vivo measurements using a unilateral magnet
    2.
    发明授权
    Nuclear magnetic resonance systems and methods for noninvasive and in-vivo measurements using a unilateral magnet 有权

    公开(公告)号：US11540766B2

    公开(公告)日：2023-01-03

    申请号：US16178317

    申请日：2018-11-01

    Applicant: Livivos Inc.

    Inventor： Pablo Jose Prado

    IPC: G01R33/46 ,  A61B5/00 ,  A61B5/055 ,  G01R33/38 ,  G01R33/48 ,  G01R33/383

    Abstract: An apparatus for non-invasive evaluations and in-vivo diagnostics includes an open magnet, an RF antenna, and an NMR analytics logical circuit communicatively coupled to the RF antenna, wherein the open magnet is shaped to generate a static magnetic field that extends unilaterally into an object or internal organ of a subject when the open magnet is positioned against or in proximity to the object or subject, the static and RF magnetic fields shaped to generate a sensitive volume within a target region. The RF antenna or antenna array is configured to transmit RF pulses into the target region of the object or internal organ and receive sets of NMR signals generated by hydrogen or other elements, and the NMR analytics logical circuit is configured to obtain and analyze sets of NMR signals.

    NUCLEAR MAGNETIC RESONANCE SYSTEMS AND METHODS FOR NONINVASIVE AND IN-VIVO MEASUREMENTS USING A UNILATERAL MAGNET
    4.
    发明申请
    NUCLEAR MAGNETIC RESONANCE SYSTEMS AND METHODS FOR NONINVASIVE AND IN-VIVO MEASUREMENTS USING A UNILATERAL MAGNET 审中-公开

    公开(公告)号：US20190076080A1

    公开(公告)日：2019-03-14

    申请号：US16178317

    申请日：2018-11-01

    Applicant: Livivos Inc.

    Inventor： Pablo Jose Prado

    IPC: A61B5/00 ,  G01R33/46 ,  A61B5/055

    Abstract: An apparatus for non-invasive evaluations and in-vivo diagnostics includes an open magnet, an RF antenna, and an NMR analytics logical circuit communicatively coupled to the RF antenna, wherein the open magnet is shaped to generate a static magnetic field that extends unilaterally into an object or internal organ of a subject when the open magnet is positioned against or in proximity to the object or subject, the static and RF magnetic fields shaped to generate a sensitive volume within a target region. The RF antenna or antenna array is configured to transmit RF pulses into the target region of the object or internal organ and receive sets of NMR signals generated by hydrogen or other elements, and the NMR analytics logical circuit is configured to obtain and analyze sets of NMR signals.

    SYSTEMS AND METHODS FOR NON-INVASIVE FAT COMPOSITION MEASUREMENT IN AN ORGAN
    5.
    发明申请
    SYSTEMS AND METHODS FOR NON-INVASIVE FAT COMPOSITION MEASUREMENT IN AN ORGAN 有权

    公开(公告)号：US20220287635A1

    公开(公告)日：2022-09-15

    申请号：US17692002

    申请日：2022-03-10

    Applicant: Livivos Inc.

    Inventor： Pablo Jose Prado ,  Alejandro Bussandri

    IPC: A61B5/00 ,  A61B5/055 ,  G01R33/48

    Abstract: Systems and methods are provided for determine the fat composition in an organ of interest using a non-invasive health measurement system. The non-invasive health measurement system may include an open magnet NMR apparatus. The NMR apparatus may measure NMR signals in a sensitive volume of a patient. The sensitive volume may coincide with an organ of interest, such as a liver. Systems and methods disclosed herein may provide for separation of the water contribution and the fat contribution to the measured NMR signal. Diffusion based separation, T2 based separation, and T1 based separation may each serve as different methods for separating the water and fat contributions to the signal. Separating the water and fat contributions to the single may allow for computation of a proton density fat fraction which may reflect the fat composition of the organ of interest.

    Systems and methods for non-invasive fat composition measurement in an organ
    6.
    发明授权
    Systems and methods for non-invasive fat composition measurement in an organ 有权

    公开(公告)号：US11896392B2

    公开(公告)日：2024-02-13

    申请号：US17692002

    申请日：2022-03-10

    Applicant: Livivos Inc.

    Inventor： Pablo Jose Prado ,  Alejandro Bussandri

    IPC: A61B5/00 ,  A61B5/055 ,  G01R33/48

    CPC classification number: A61B5/4872 ,  A61B5/055 ,  G01R33/4828

    Abstract: Systems and methods are provided for determine the fat composition in an organ of interest using a non-invasive health measurement system. The non-invasive health measurement system may include an open magnet NMR apparatus. The NMR apparatus may measure NMR signals in a sensitive volume of a patient. The sensitive volume may coincide with an organ of interest, such as a liver. Systems and methods disclosed herein may provide for separation of the water contribution and the fat contribution to the measured NMR signal. Diffusion based separation, T2 based separation, and T1 based separation may each serve as different methods for separating the water and fat contributions to the signal. Separating the water and fat contributions to the single may allow for computation of a proton density fat fraction which may reflect the fat composition of the organ of interest.

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