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    Antibodies directed to parathyroid hormone (PTH) and uses thereof
    1.
    发明授权
    Antibodies directed to parathyroid hormone (PTH) and uses thereof 失效
    针对甲状旁腺激素（PTH）的抗体及其用途

    公开(公告)号：US07288253B2

    公开(公告)日：2007-10-30

    申请号：US10638265

    申请日：2003-08-08

    申请人： Lorin Roskos ,  Ian Foltz ,  Chadwick King

    发明人： Lorin Roskos ,  Ian Foltz ,  Chadwick King

    IPC分类号： A61K39/395 ,  A61K39/00 ,  A01N37/18

    CPC分类号： C07K16/26 ,  A01K2217/075 ,  A61K2039/505 ,  C07K2317/21 ,  C07K2317/34 ,  C07K2317/76 ,  C07K2317/92

    摘要： Embodiments of the invention described herein relate to antibodies directed to the antigen parathyroid hormone (PTH) and uses of such antibodies. In particular, in some embodiments, there are provided fully human monoclonal antibodies directed to the antigen PTH. In further embodiments, nucleotide sequences encoding, and amino acid sequences comprising, heavy and light chain immunoglobulin molecules, particularly sequences corresponding to contiguous heavy and light chain sequences spanning the framework regions and/or complementarity determining regions (CDRs), specifically from FR1 through FR4 or CDR1 through CDR3, are provided.

    摘要翻译： 本文描述的本发明的实施方案涉及针对抗原甲状旁腺激素（PTH）的抗体和这种抗体的用途。 特别地，在一些实施方案中，提供针对抗原PTH的完全人单克隆抗体。 在另外的实施方案中，编码的核苷酸序列和包含重链和轻链免疫球蛋白分子的氨基酸序列，特别是对应于横跨框架区和/或互补决定区（CDR）的连续重链和轻链序列的序列，特别是FR1至FR4 或CDR1至CDR3。

    Antibodies against parathyroid hormone
    2.
    发明申请
    Antibodies against parathyroid hormone 失效
    甲状旁腺激素抗体

    公开(公告)号：US20060062783A1

    公开(公告)日：2006-03-23

    申请号：US10956008

    申请日：2004-09-30

    申请人： Lorin Roskos ,  Ian Foltz ,  Chadwick King ,  Gregory Bell

    发明人： Lorin Roskos ,  Ian Foltz ,  Chadwick King ,  Gregory Bell

    IPC分类号： A61K39/395

    CPC分类号： C07K16/26 ,  A61K2039/505 ,  C07K2317/21 ,  C07K2317/34 ,  C07K2317/565 ,  C07K2317/567 ,  C07K2317/76 ,  C07K2317/92

    摘要： Embodiments of the invention described herein relate to antibodies directed to the antigen parathyroid hormone (PTH) and uses of such antibodies. In particular, in some embodiments, there are provided fully human monoclonal antibodies directed to the antigen PTH. In further embodiments, nucleotide sequences encoding, and amino acid sequences comprising, heavy and light chain immunoglobulin molecules, particularly sequences corresponding to contiguous heavy and light chain sequences spanning the framework regions and/or complementarity determining regions (CDRs), specifically from FR1 through FR4 or CDR1 through CDR3, are provided.

    摘要翻译： 本文描述的本发明的实施方案涉及针对抗原甲状旁腺激素（PTH）的抗体和这种抗体的用途。 特别地，在一些实施方案中，提供针对抗原PTH的完全人单克隆抗体。 在另外的实施方案中，编码的核苷酸序列和包含重链和轻链免疫球蛋白分子的氨基酸序列，特别是对应于横跨框架区和/或互补决定区（CDR）的连续重链和轻链序列的序列，特别是FR1至FR4 或CDR1至CDR3。

    Methods of use for antibodies against parathyroid hormone
    3.
    发明授权
    Methods of use for antibodies against parathyroid hormone 失效
    甲状旁腺激素抗体的使用方法

    公开(公告)号：US07318925B2

    公开(公告)日：2008-01-15

    申请号：US10956008

    申请日：2004-09-30

    申请人： Lorin Roskos ,  Ian Foltz ,  Chadwick King ,  Gregory Bell

    发明人： Lorin Roskos ,  Ian Foltz ,  Chadwick King ,  Gregory Bell

    IPC分类号： C07K16/18 ,  C07K16/26

    CPC分类号： C07K16/26 ,  A61K2039/505 ,  C07K2317/21 ,  C07K2317/34 ,  C07K2317/565 ,  C07K2317/567 ,  C07K2317/76 ,  C07K2317/92

    摘要： Embodiments of the invention described herein relate to antibodies directed to the antigen parathyroid hormone (PTH) and uses of such antibodies. In particular, in some embodiments, there are provided fully human monoclonal antibodies directed to the antigen PTH. In further embodiments, nucleotide sequences encoding, and amino acid sequences comprising, heavy and light chain immunoglobulin molecules, particularly sequences corresponding to contiguous heavy and light chain sequences spanning the framework regions and/or complementarity determining regions (CDRs), specifically from FR1 through FR4 or CDR1 through CDR3, are provided.

    摘要翻译： 本文描述的本发明的实施方案涉及针对抗原甲状旁腺激素（PTH）的抗体和这种抗体的用途。 特别地，在一些实施方案中，提供针对抗原PTH的完全人单克隆抗体。 在另外的实施方案中，编码的核苷酸序列和包含重链和轻链免疫球蛋白分子的氨基酸序列，特别是对应于横跨框架区和/或互补决定区（CDR）的连续重链和轻链序列的序列，特别是FR1至FR4 或CDR1至CDR3。

    Antibodies directed to parathyroid hormone (PTH) and uses thereof
    4.
    发明申请
    Antibodies directed to parathyroid hormone (PTH) and uses thereof 失效
    针对甲状旁腺激素（PTH）的抗体及其用途

    公开(公告)号：US20050031614A1

    公开(公告)日：2005-02-10

    申请号：US10638265

    申请日：2003-08-08

    申请人： Lorin Roskos ,  Ian Foltz ,  Chadwick King

    发明人： Lorin Roskos ,  Ian Foltz ,  Chadwick King

    IPC分类号： C07K16/26 ,  A61K39/395

    CPC分类号： C07K16/26 ,  A01K2217/075 ,  A61K2039/505 ,  C07K2317/21 ,  C07K2317/34 ,  C07K2317/76 ,  C07K2317/92

    摘要： Embodiments of the invention described herein relate to antibodies directed to the antigen parathyroid hormone (PTH) and uses of such antibodies. In particular, in some embodiments, there are provided fully human monoclonal antibodies directed to the antigen PTH. In further embodiments, nucleotide sequences encoding, and amino acid sequences comprising, heavy and light chain immunoglobulin molecules, particularly sequences corresponding to contiguous heavy and light chain sequences spanning the framework regions and/or complementarity determining regions (CDRs), specifically from FR1 through FR4 or CDR1 through CDR3, are provided.

    摘要翻译： 本文描述的本发明的实施方案涉及针对抗原甲状旁腺激素（PTH）的抗体和这种抗体的用途。 特别地，在一些实施方案中，提供针对抗原PTH的完全人单克隆抗体。 在另外的实施方案中，编码的核苷酸序列和包含重链和轻链免疫球蛋白分子的氨基酸序列，特别是对应于跨越框架区和/或互补决定区（CDR）的连续重链和轻链序列的序列，特别是FR1至FR4 或CDR1至CDR3。