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公开(公告)号:US07320788B2
公开(公告)日:2008-01-22
申请号:US10969314
申请日:2004-10-19
申请人: Lu Shan , Michael Bethune , Chaitan Khosla , Jonathan Gass , Gail G. Pyle , Gary Gray
发明人: Lu Shan , Michael Bethune , Chaitan Khosla , Jonathan Gass , Gail G. Pyle , Gary Gray
CPC分类号: A61K38/4813 , A23L29/06 , A61K38/482
摘要: Administering an effective dose of glutenase to a Celiac or dermatitis herpetiformis patient reduces levels of toxic gluten oligopeptides, thereby attenuating or eliminating the damaging effects of gluten.
摘要翻译: 将有效剂量的谷蛋白酶施用于腹腔炎或疱疹样皮炎患者可降低毒性麸质寡肽的含量,从而减弱或消除麸质的破坏作用。
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公开(公告)号:US08796201B2
公开(公告)日:2014-08-05
申请号:US13289924
申请日:2011-11-04
申请人: Lu Shan , Michael Bethune , Chaitan Khosla , Jonathan Gass , Gail G. Pyle , Gary M. Gray , Indu Isaacs , Gregg Strohmeier
发明人: Lu Shan , Michael Bethune , Chaitan Khosla , Jonathan Gass , Gail G. Pyle , Gary M. Gray , Indu Isaacs , Gregg Strohmeier
CPC分类号: A61K38/48
摘要: Administering an effective dose of glutenase to a Celiac or dermatitis herpetiformis patient reduces levels of toxic gluten oligopeptides, thereby attenuating or eliminating the damaging effects of gluten.
摘要翻译: 将有效剂量的谷蛋白酶施用于腹腔炎或疱疹样皮炎患者可降低毒性麸质寡肽的含量,从而减弱或消除麸质的破坏作用。
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公开(公告)号:US20120156253A1
公开(公告)日:2012-06-21
申请号:US13289924
申请日:2011-11-04
申请人: Lu Shan , Michael Bethune , Chaitan Khosla , Jonathan Gass , Gail G. Pyle , Gary M. Gray , Indu Isaacs , Gregg Strohmeier
发明人: Lu Shan , Michael Bethune , Chaitan Khosla , Jonathan Gass , Gail G. Pyle , Gary M. Gray , Indu Isaacs , Gregg Strohmeier
CPC分类号: A61K38/48
摘要: Administering an effective dose of glutenase to a Celiac or dermatitis herpetiformis patient reduces levels of toxic gluten oligopeptides, thereby attenuating or eliminating the damaging effects of gluten.
摘要翻译: 将有效剂量的谷蛋白酶施用于腹腔炎或疱疹样皮炎患者可降低毒性麸质寡肽的含量,从而减弱或消除麸质的破坏作用。
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公开(公告)号:US20050249719A1
公开(公告)日:2005-11-10
申请号:US10969314
申请日:2004-10-19
申请人: Lu Shan , Michael Bethune , Chaitan Khosla , Jonathan Gass , Gail Pyle , Gary Gray , Indu Isaacs , Gregg Strohmeier
发明人: Lu Shan , Michael Bethune , Chaitan Khosla , Jonathan Gass , Gail Pyle , Gary Gray , Indu Isaacs , Gregg Strohmeier
CPC分类号: A61K38/4813 , A23L29/06 , A61K38/482
摘要: Administering an effective dose of glutenase to a Celiac or dermatitis herpetiformis patient reduces levels of toxic gluten oligopeptides, thereby attenuating or eliminating the damaging effects of gluten.
摘要翻译: 将有效剂量的谷蛋白酶施用于腹腔炎或疱疹样皮炎患者可降低毒性麸质寡肽的含量,从而减弱或消除麸质的破坏作用。
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公开(公告)号:US20080095710A1
公开(公告)日:2008-04-24
申请号:US11775824
申请日:2007-07-10
申请人: Lu Shan , Michael Bethune , Chaitan Khosla , Jonathan Gass , Gail Pyle , Gary Gray , Indu Isaacs , Gregg Strohmeier
发明人: Lu Shan , Michael Bethune , Chaitan Khosla , Jonathan Gass , Gail Pyle , Gary Gray , Indu Isaacs , Gregg Strohmeier
CPC分类号: A61K38/4813 , A61K38/482
摘要: Administering an effective dose of glutenase to a Celiac or dermatitis herpetiformis patient reduces levels of toxic gluten oligopeptides, thereby attenuating or eliminating the damaging effects of gluten.
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公开(公告)号:US20080193436A1
公开(公告)日:2008-08-14
申请号:US11587217
申请日:2005-02-23
申请人: Lu Shan , Michael Bethune , Chaitan Khosla , Jonathan David Gass
发明人: Lu Shan , Michael Bethune , Chaitan Khosla , Jonathan David Gass
IPC分类号: A61K38/48
CPC分类号: A61K38/4813 , A61K38/482 , Y02A50/473
摘要: Pharmaceutical formulations of glutenase enzymes are provided. The enzymes find particular use in the treatment of a Celiac or dermatitis herpetiformis patient.
摘要翻译: 提供谷蛋白酶的药物制剂。 这些酶特别用于治疗腹膜炎或疱疹样皮炎患者。
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公开(公告)号:US07943312B2
公开(公告)日:2011-05-17
申请号:US11927525
申请日:2007-10-29
申请人: Felix Hausch , Gary Gray , Lu Shan , Chaitan Khosla
发明人: Felix Hausch , Gary Gray , Lu Shan , Chaitan Khosla
CPC分类号: A61K38/482 , A23L29/06 , A23L33/10 , A23V2002/00 , A61K9/0053 , A61K9/2009 , A61K9/2013 , A61K9/2031 , A61K9/2866 , A61K9/4825 , A61K9/485 , A61K9/4891 , A61K31/42 , A61K38/4813 , C07D261/04 , C07D413/12 , C07K14/415 , C07K16/16 , C07K2317/34 , C12Y304/14005 , C12Y304/15001 , C12Y304/21026 , G01N33/564 , G01N33/6854 , G01N2800/06 , G01N2800/202 , Y02A50/473
摘要: Administering an effective dose of glutenase to a Celiac or dermatitis herpetiformis patient reduces levels of toxic gluten oligopeptides, thereby attenuating or eliminating the damaging effects of gluten.
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公开(公告)号:US07910541B2
公开(公告)日:2011-03-22
申请号:US11927532
申请日:2007-10-29
申请人: Felix Hausch , Gary Gray , Lu Shan , Chaitan Khosla
发明人: Felix Hausch , Gary Gray , Lu Shan , Chaitan Khosla
CPC分类号: A61K38/482 , A23L29/06 , A23L33/10 , A23V2002/00 , A61K9/0053 , A61K9/2009 , A61K9/2013 , A61K9/2031 , A61K9/2866 , A61K9/4825 , A61K9/485 , A61K9/4891 , A61K31/42 , A61K38/4813 , C07D261/04 , C07D413/12 , C07K14/415 , C07K16/16 , C07K2317/34 , C12Y304/14005 , C12Y304/15001 , C12Y304/21026 , G01N33/564 , G01N33/6854 , G01N2800/06 , G01N2800/202 , Y02A50/473
摘要: Administering an effective dose of glutenase to a Celiac or dermatitis herpetiformis patient reduces levels of toxic gluten oligopeptides, thereby attenuating or eliminating the damaging effects of gluten.
摘要翻译: 将有效剂量的谷蛋白酶施用于腹腔炎或疱疹样皮炎患者可降低毒性麸质寡肽的含量,从而减弱或消除麸质的破坏作用。
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公开(公告)号:US20080213427A1
公开(公告)日:2008-09-04
申请号:US11927532
申请日:2007-10-29
申请人: Felix Hausch , Gary Gray , Lu Shan , Chaitan Khosla
发明人: Felix Hausch , Gary Gray , Lu Shan , Chaitan Khosla
CPC分类号: A61K38/482 , A23L29/06 , A23L33/10 , A23V2002/00 , A61K9/0053 , A61K9/2009 , A61K9/2013 , A61K9/2031 , A61K9/2866 , A61K9/4825 , A61K9/485 , A61K9/4891 , A61K31/42 , A61K38/4813 , C07D261/04 , C07D413/12 , C07K14/415 , C07K16/16 , C07K2317/34 , C12Y304/14005 , C12Y304/15001 , C12Y304/21026 , G01N33/564 , G01N33/6854 , G01N2800/06 , G01N2800/202 , Y02A50/473
摘要: Administering an effective dose of glutenase to a Celiac or dermatitis herpetiformis patient reduces levels of toxic gluten oligopeptides, thereby attenuating or eliminating the damaging effects of gluten.
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公开(公告)号:US20110293724A1
公开(公告)日:2011-12-01
申请号:US13053120
申请日:2011-03-21
申请人: Felix Hausch , Gary Gray , Lu Shan , Chaitan Khosla
发明人: Felix Hausch , Gary Gray , Lu Shan , Chaitan Khosla
CPC分类号: A61K38/482 , A23L29/06 , A23L33/10 , A23V2002/00 , A61K9/0053 , A61K9/2009 , A61K9/2013 , A61K9/2031 , A61K9/2866 , A61K9/4825 , A61K9/485 , A61K9/4891 , A61K31/42 , A61K38/4813 , C07D261/04 , C07D413/12 , C07K14/415 , C07K16/16 , C07K2317/34 , C12Y304/14005 , C12Y304/15001 , C12Y304/21026 , G01N33/564 , G01N33/6854 , G01N2800/06 , G01N2800/202 , Y02A50/473
摘要: Administering an effective dose of glutenase to a Celiac or dermatitis herpetiformis patient reduces levels of toxic gluten oligopeptides, thereby attenuating or eliminating the damaging effects of gluten.
摘要翻译: 将有效剂量的谷蛋白酶施用于腹腔炎或疱疹样皮炎患者可降低毒性麸质寡肽的含量,从而减弱或消除麸质的破坏作用。
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