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16 条记录 (耗时 0.026 秒)

    Methods, Agents, and Compound Screening Assays for Inducing Differentiation of Undifferentiated Mammalian Cells into Osteoblasts
    2.
    发明申请
    Methods, Agents, and Compound Screening Assays for Inducing Differentiation of Undifferentiated Mammalian Cells into Osteoblasts 失效
    用于诱导未分化哺乳动物细胞分化成成骨细胞的方法，试剂和化合物筛选试验

    公开(公告)号：US20070184026A1

    公开(公告)日：2007-08-09

    申请号：US11551744

    申请日：2006-10-23

    申请人： Luc Van Rompaey ,  Peter Tomme ,  Robin Brown

    发明人： Luc Van Rompaey ,  Peter Tomme ,  Robin Brown

    IPC分类号： A61K48/00 ,  C40B30/06 ,  C40B40/08 ,  C40B40/10 ,  C12N15/86

    CPC分类号： G01N33/566 ,  C12N15/111 ,  C12N2310/111 ,  C12N2310/14 ,  C12N2310/53 ,  C12N2320/11 ,  C12N2320/12 ,  G01N33/5026 ,  G01N2333/51 ,  G01N2500/04 ,  G01N2800/108

    摘要： The present invention relates to methods, agents and compound screening assays for inducing differentiation of undifferentiated mammalian cells into osteoblasts. The invention thus provides a method, comprising contacting a compound with a polypeptide comprising an amino acid sequence selected from the group consisting of SEQ ID No: 194-309; and measuring a compound-polypeptide property related to the differentiation of said cells. The invention further relates to a bone formation enhancing pharmaceutical composition, and the use thereof in treating and/or preventing a disease involving a systemic or local decrease in mean bone density in a subject. Furthermore, the invention relates to a method for the in vitro production of bone tissue.

    摘要翻译： 本发明涉及用于诱导未分化的哺乳动物细胞分化成成骨细胞的方法，试剂和化合物筛选试验。 因此，本发明提供了一种方法，包括使化合物与包含选自SEQ ID No：194-309的氨基酸序列的多肽接触; 并测量与所述细胞的分化相关的化合物 - 多肽性质。 本发明进一步涉及增强骨形成的药物组合物，以及其在治疗和/或预防受试者的全身或局部平均骨密度降低的疾病中的用途。 此外，本发明涉及体外生产骨组织的方法。

    Test device and method
    3.
    发明授权
    Test device and method 有权
    测试装置和方法

    公开(公告)号：US09482623B2

    公开(公告)日：2016-11-01

    申请号：US13502483

    申请日：2010-10-21

    申请人： Robin Brown

    发明人： Robin Brown

    IPC分类号： B01L3/00 ,  G01N21/84 ,  G01N33/53

    CPC分类号： G01N21/8483 ,  B01L3/50 ,  B01L3/502715 ,  B01L3/5029

    摘要： A connection assembly for a test device comprises a carriage for receiving at least a portion of a test device and a receptacle for co-operation with the carriage. The carriage is longitudinally movable with respect to the receptacle and is latchable to the receptacle at a predetermined position.

    摘要翻译： 用于测试装置的连接组件包括用于接收测试装置的至少一部分的托架和用于与托架协同操作的插座。 托架可相对于插座纵向移动，并且可在预定位置处闩锁到插座。

    Vapor control set screw valve
    4.
    发明申请
    Vapor control set screw valve 有权

    公开(公告)号：US20220402748A1

    公开(公告)日：2022-12-22

    申请号：US17803260

    申请日：2022-04-06

    申请人： Theodore Cosgrove ,  Robin Brown ,  Grenville Sutcliffe ,  Theodore Sutcliffe

    发明人： Theodore Cosgrove ,  Robin Brown ,  Grenville Sutcliffe ,  Theodore Sutcliffe

    IPC分类号： B67D7/44 ,  F16K3/24

    摘要： A vapor control set screw valve applied into the handle of a fuel dispensing nozzle, including a valve bushing intermediately applied within the vapor return line within the handle, a set screw valve provided within the lateral channel formed of the bushing, an insert bushing applied to the dispenser handle, and the set screw, forming the valve, engaging within the insert bushing, and extending into the vapor return line bushing, to provide for its adjustment therein, to open or close the vapor return line within the nozzle in order to regulate and control the flow of the returning vapors being pumped back to the associated dispenser, and to the normally underground fuel storage tank associated with gasoline dispensing.

    RETAIL EQUIPMENT
    5.
    发明申请
    RETAIL EQUIPMENT 审中-公开
    零售设备

    公开(公告)号：US20140006193A1

    公开(公告)日：2014-01-02

    申请号：US13979494

    申请日：2012-01-12

    申请人： Rupert Holt ,  Robin Brown

    发明人： Rupert Holt ,  Robin Brown

    IPC分类号： G06Q20/20

    CPC分类号： G06Q20/202 ,  G06Q20/20 ,  G06Q30/06 ,  G07G1/14

    摘要： According to one aspect, the present invention resides in an electronic transaction system for managing transactions related to items selected by a user, such as a checkout POS terminal for example. The system comprises a first transaction module arranged to manage transactions in respect of local items supplied within a retail environment; a data store arranged to store updatable data relating to remote items provided by a remote server; and a second transaction module arranged to access the updatable data to provide access to the remote items via the electronic transaction system.

    摘要翻译： 根据一个方面，本发明涉及一种电子交易系统，用于管理例如诸如结账POS终端之类的用户选择的项目的交易。 该系统包括第一交易模块，其被布置为管理关于在零售环境内提供的本地物品的交易; 数据存储装置，用于存储与由远程服务器提供的远程项相关的可更新数据; 以及第二交易模块，被布置为访问所述可更新数据以经由所述电子交易系统提供对所述远程物品的访问。

    Pond filter
    7.
    外观设计
    Pond filter 有权
    池过滤器

    公开(公告)号：USD547824S1

    公开(公告)日：2007-07-31

    申请号：US29243791

    申请日：2005-11-30

    申请人： Robin Brown

    设计人： Robin Brown

    Hidden chamber candle jar housing
    8.
    发明申请
    Hidden chamber candle jar housing 审中-公开
    隐藏室蜡烛房

    公开(公告)号：US20050244767A1

    公开(公告)日：2005-11-03

    申请号：US10836947

    申请日：2004-04-30

    申请人： Robin Brown

    发明人： Robin Brown

    IPC分类号： A61L9/03 ,  F21S13/12 ,  F21V17/00 ,  F21V35/00 ,  F21V37/00 ,  F23D3/16

    CPC分类号： A61L9/03 ,  F21S13/12 ,  F21V17/007 ,  F21V35/00 ,  F21V37/00

    摘要： The present invention provides a housing having a hollow enclosure with at least one side wall. A first opening on a first portion of the enclosure is provided for receiving a candle jar therethrough, and a second opening on a second portion of the enclosure is provided for receiving a candle jar lid therethrough. A shelf is positioned within the enclosure to separate the first and second portions. The shelf includes a surface facing the first portion for supporting a candle jar.

    摘要翻译： 本发明提供一种具有至少一个侧壁的具有中空外壳的壳体。 设置在外壳的第一部分上的第一开口用于容纳通过其中的蜡烛罐，并且设置在外壳的第二部分上的第二开口用于容纳通过其中的蜡烛罐盖。 一个搁板定位在外壳内以分离第一和第二部分。 搁板包括面向第一部分以支撑蜡烛罐的表面。

    Batting helmet with adjustable face guard
    10.
    发明申请
    Batting helmet with adjustable face guard 审中-公开
    用可调节的面部护罩打击头盔

    公开(公告)号：US20070250992A1

    公开(公告)日：2007-11-01

    申请号：US11414671

    申请日：2006-04-28

    申请人： Robin Brown

    发明人： Robin Brown

    IPC分类号： A42B1/08

    CPC分类号： A42B3/20

    摘要： A batting helmet with an adjustable face guard includes a rigid shell for protecting the head of a wearer, with an adjustable face guard movably attached to the shell. An adjustment mechanism regulates the movement of the face guard between upper and lower limits to vary a wearer's line-of-sight through the face guard. An associated method of use is also provided

    摘要翻译： 具有可调节面罩的蝙蝠头盔包括用于保护佩戴者头部的刚性外壳，具有可移动地附接到外壳的可调节面罩。 调节机构调节脸部护罩在上限和下限之间的运动，以改变穿戴者通过面部护罩的视线。 还提供了相关联的使用方法