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公开(公告)号：US20140377783A1
公开(公告)日：2014-12-25
申请号：US13883067
申请日：2011-11-04
申请人： Lukas Wick , Urs Spitz , Christophe Weymuth , Günter Schabert , Thomas Mayer , Alexander Bayer
发明人： Lukas Wick , Urs Spitz , Christophe Weymuth , Günter Schabert , Thomas Mayer , Alexander Bayer
CPC分类号： G01N33/583 , C09B57/00 , C09B67/0083 , C12Q1/04 , C12Q1/10 , C12Q1/34 , C12Q1/44 , G01N2333/938
摘要： A novel type of dye systems comprises a selection of 10H-indolo[1,2-a]indole compounds (henceforth abbreviated as IO compounds) and (5H,7H)-indolo[1,2-a]quinoline compounds (henceforth abbreviated as IQ compounds) showing a solvatochromic effect and exhibiting strong fluorescence in a variety of materials such as polypropylene, polyethylene, oils, various solvents, emulsions. Also disclosed are various methods how the IO/IQ compounds can be administered, especially how they can be produced and administered in situ from a precursor, responding to external stimuli such as enzyme activity, temperature and so forth. The response of a precursor to external stimuli can also be used to determine the presence or absence of such stimuli.
摘要翻译： 一种新型染料体系包括10H-吲哚并[1,2-a]吲哚化合物（以下简称为IO化合物）和（5H，7H） - 吲哚并[1,2-a]喹啉化合物（以下简称为 IQ化合物），显示出溶剂化色素效应，并在各种材料如聚丙烯，聚乙烯，油，各种溶剂，乳液中表现出强烈的荧光。 还公开了如何施用IO / IQ化合物的各种方法，特别是如何从前体产生和原位施用，对外部刺激如酶活性，温度等进行响应。 前体对外部刺激的反应也可以用于确定这种刺激的存在或不存在。
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公开(公告)号：US09157917B2
公开(公告)日：2015-10-13
申请号：US13883067
申请日：2011-11-04
申请人： Lukas Wick , Urs Spitz , Christophe Weymuth , Günter Schabert , Thomas Mayer , Alexander Bayer
发明人： Lukas Wick , Urs Spitz , Christophe Weymuth , Günter Schabert , Thomas Mayer , Alexander Bayer
IPC分类号： C07D221/18 , C09B67/08 , G01N33/58 , C09B57/00 , C09B67/44 , C12Q1/04 , C12Q1/10 , C12Q1/34 , C12Q1/44
CPC分类号： G01N33/583 , C09B57/00 , C09B67/0083 , C12Q1/04 , C12Q1/10 , C12Q1/34 , C12Q1/44 , G01N2333/938
摘要： A novel type of dye systems comprises a selection of 10H-indolo[1,2-a]indole compounds (henceforth abbreviated as IO compounds) and (5H,7H)-indolo[1,2-a]quinoline compounds (henceforth abbreviated as IQ compounds) showing a solvatochromic effect and exhibiting strong fluorescence in a variety of materials such as polypropylene, polyethylene, oils, various solvents, emulsions. Also disclosed are various methods how the IO/IQ compounds can be administered, especially how they can be produced and administered in situ from a precursor, responding to external stimuli such as enzyme activity, temperature and so forth. The response of a precursor to external stimuli can also be used to determine the presence or absence of such stimuli.
摘要翻译： 一种新型染料体系包括10H-吲哚并[1,2-a]吲哚化合物（以下简称为IO化合物）和（5H，7H） - 吲哚并[1,2-a]喹啉化合物（以下简称为 IQ化合物），显示出溶剂化色素效应，并在各种材料如聚丙烯，聚乙烯，油，各种溶剂，乳液中表现出强烈的荧光。 还公开了如何施用IO / IQ化合物的各种方法，特别是如何从前体产生和原位施用，对外部刺激如酶活性，温度等进行响应。 前体对外部刺激的反应也可以用于确定这种刺激的存在或不存在。
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公开(公告)号：US20120058503A1
公开(公告)日：2012-03-08
申请号：US13266707
申请日：2010-05-06
申请人： Urs Spitz , Lukas Wick , Alexander Bayer , Christophe Weymuth , Günter Schabert
发明人： Urs Spitz , Lukas Wick , Alexander Bayer , Christophe Weymuth , Günter Schabert
CPC分类号： C07D209/36 , C07D209/70 , C07D487/04
摘要： A novel indicator platform comprises a plurality of 1H-lndol-3-yl indicator compounds that are capable of converting to a signalophore compound in response to an external stimulus. In one class of indicator compounds, the resulting signalophores are 2-benzylideneindoline compounds that are formed by an intermolecular Aldol-type process; in a further class of indicator compounds, the resulting signalophores are 10H-indolo[1,2-a]indole compounds that are formed by an intramolecular Aldol-type process. The indicators can be used in a wide array of applications relating, for example, to biological systems or optical data storage.
摘要翻译： 一种新颖的指示剂平台包含能够响应外部刺激转化成信号载体化合物的多个1H-吲哚-3-基指示剂化合物。 在一类指示剂化合物中，所得到的信号聚合物是通过分子间Aldol型方法形成的2-亚苄基二氢吲哚化合物; 在另一类指示剂化合物中，所得到的信号聚合物是通过分子内Aldol型方法形成的10H-吲哚并[1,2-a]吲哚化合物。 这些指标可用于涉及例如生物系统或光学数据存储的广泛应用。
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公开(公告)号：US08940909B2
公开(公告)日：2015-01-27
申请号：US13266707
申请日：2010-05-06
申请人： Urs Spitz , Lukas Wick , Alexander Bayer , Christophe Weymuth , Günter Schabert
发明人： Urs Spitz , Lukas Wick , Alexander Bayer , Christophe Weymuth , Günter Schabert
IPC分类号： C07D209/70 , C07D209/36 , C07D487/04
CPC分类号： C07D209/36 , C07D209/70 , C07D487/04
摘要： A novel indicator platform comprises a plurality of 1H-lndol-3-yl indicator compounds that are capable of converting to a signalophore compound in response to an external stimulus. In one class of indicator compounds, the resulting signalophores are 2-benzylideneindoline compounds that are formed by an intermolecular Aldol-type process; in a further class of indicator compounds, the resulting signalophores are 10H-indolo[1,2-a]indole compounds that are formed by an intramolecular Aldol-type process. The indicators can be used in a wide array of applications relating, for example, to biological systems or optical data storage.
摘要翻译： 一种新颖的指示剂平台包含能够响应外部刺激转化成信号载体化合物的多个1H-吲哚-3-基指示剂化合物。 在一类指示剂化合物中，所得到的信号聚合物是通过分子间Aldol型方法形成的2-亚苄基二氢吲哚化合物; 在另一类指示剂化合物中，所得到的信号聚合物是通过分子内Aldol型方法形成的10H-吲哚并[1,2-a]吲哚化合物。 这些指标可用于涉及例如生物系统或光学数据存储的广泛应用。
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