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4 条记录 (耗时 0.017 秒)

    Device and method for the parallel separation of substances by liquid chromatography
    1.
    发明授权
    Device and method for the parallel separation of substances by liquid chromatography 有权
    通过液相色谱法并行分离物质的装置和方法

    公开(公告)号：US06911151B1

    公开(公告)日：2005-06-28

    申请号：US09856099

    申请日：1999-11-22

    申请人： Lutz Müller-Kuhrt ,  Ralf God ,  Holger Gumm ,  Jörg Binkele

    发明人： Lutz Müller-Kuhrt ,  Ralf God ,  Holger Gumm ,  Jörg Binkele

    IPC分类号： B01D15/08 ,  G01N30/02 ,  G01N30/06 ,  G01N30/32 ,  G01N30/46

    CPC分类号： G01N30/466 ,  B01D15/14 ,  B01D15/1885 ,  G01N30/02 ,  G01N30/32 ,  G01N2030/062 ,  G01N2030/065 ,  G01N2030/324 ,  B01D15/40

    摘要： The invention relates to a device and a method for separating substances by liquid chromatography. The aim of the invention is to provide a device and a method by which means substances can be separated by liquid chromatography under pressure and which enable parallel separation and detection of at least several samples. The device should have a compact, economical construction. To this end, the inventive device for separating substances by liquid chromatography under pressure is characterized in that at least several liquid chromatography separating lines (17) are supplied by a single delivery unit (one or two pumps), said separating lines being arranged so that they run parallel, and in that said separating lines are combined with a sample-loading system (5) and an injection system (18) in the sample introduction area and with a multi-channel detector (13), connected to an evaluation and control unit (16), in the detection area.

    摘要翻译： 本发明涉及通过液相色谱分离物质的装置和方法。 本发明的目的是提供一种装置和方法，通过该装置和方法，可以在压力下通过液相色谱分离物质，并且能够平行分离和检测至少几种样品。 该设备应具有紧凑，经济的结构。 为此，用于通过液相色谱在压力下分离物质的本发明装置的特征在于，至少几个液相色谱分离管线（17）由单个输送单元（一个或两个泵）供应，所述分离管线被布置成使得 它们并行运行，并且所述分离线与样品引入区域中的样品加载系统（5）和注射系统（18）以及连接到评估和控制的多通道检测器（13）组合 单元（16），在检测区域。

    Method and device for regulating individual sub-flows of a system for conveying fluid media
    2.
    发明授权
    Method and device for regulating individual sub-flows of a system for conveying fluid media 有权
    用于调节用于输送流体介质的系统的各个子流的方法和装置

    公开(公告)号：US06532978B1

    公开(公告)日：2003-03-18

    申请号：US09856131

    申请日：2001-08-06

    申请人： Lutz Müller-Kuhrt ,  Ralf God ,  Holger Gumm ,  Jörg Binkele

    发明人： Lutz Müller-Kuhrt ,  Ralf God ,  Holger Gumm ,  Jörg Binkele

    IPC分类号： G05D706

    CPC分类号： G05D11/132 ,  G01N30/32 ,  G01N30/466 ,  Y10T137/0318 ,  Y10T137/2657 ,  Y10T137/7761 ,  Y10T137/87877

    摘要： The invention relates a method and a device for regulating individual sub-flows of a conveying system while the main flow is conveyed in a constant manner. The aim of the invention is to provide a method and a device which enable the sub-flows of the conveying lines of a system for conveying fluid media to be regulated as required in said individual conveying lines with just one conveyor unit. To this end, the inventive device for regulating individual sub-flows of a system for conveying fluid media has several conveying lines which are guided in parallel. The invention is characterized in that the following are arranged in the conveying system: at least one total pressure measuring device (10), at least one sub-flow measuring unit (D) in each conveying line, at least one valve (7) with a throttle (B) and a data acquisition, processing and control value output module (C), these being functionally interconnected by hardware and/or software.

    摘要翻译： 本发明涉及一种用于在主流以恒定方式输送的情况下调节输送系统的各个子流的方法和装置。 本发明的目的是提供一种方法和装置，其能够仅使用一个输送单元使得用于输送流体介质的输送管线的子流根据需要在所述单独的输送管线中进行调节。 为此，用于调节用于输送流体介质的系统的各个子流的本发明的装置具有并行引导的多个输送管线。 本发明的特征在于，在输送系统中设置以下装置：至少一个总压力测量装置（10），每个输送管线中的至少一个子流量测量单元（D），至少一个具有 油门（B）和数据采集，处理和控制值输出模块（C），它们通过硬件和/或软件功能互连。

    PHARMACEUTICALLY ACTIVE COMPOUNDS
    3.
    发明申请
    PHARMACEUTICALLY ACTIVE COMPOUNDS 审中-公开
    药物活性化合物

    公开(公告)号：US20100048921A1

    公开(公告)日：2010-02-25

    申请号：US12522770

    申请日：2008-01-10

    申请人： Herbert Görne ,  Lutz Müller-Kuhrt ,  Christian Mang

    发明人： Herbert Görne ,  Lutz Müller-Kuhrt ,  Christian Mang

    IPC分类号： C07D311/02

    CPC分类号： C07K5/06113 ,  A23K20/121 ,  A23K20/147 ,  A23V2002/00 ,  A61K38/00 ,  A61K47/542 ,  A61K47/64 ,  C07H17/07 ,  C07K5/0819 ,  C07K5/1021 ,  C07K7/06 ,  C07K9/001 ,  A23V2200/326 ,  A23V2200/308 ,  A23V2200/328 ,  A23V2250/061 ,  A23V2250/0618 ,  A23V2250/21172

    摘要： This invention relates to pharmaceutically active compounds consisting of an isoflavone or isoflavone-glycoside and an amino acid, a peptide or peptide derivate with 2 to 5 amino acids which is covalently bonded to these, as well as pharmaceutically acceptable salts or solvates of these compositions as well as to the use of those substances for the production of pharmaceutical compositions, in particular for the treatment of thrombocyte aggregation and tumor therapy.Consequently, the areas of application of the invention are medicine and the pharmaceutical industry.The compounds according to the invention have the general formula (I). X-Pep  (I) whereupon X is an isoflavone or isoflavone-glycoside, and Pep is an amino acid or a peptide or peptide derivate with 2 to 5 amino acids, and there is a bond between X and Pep either with a covalent bond or with a linker system.

    摘要翻译： 本发明涉及由异黄酮或异黄酮糖苷和氨基酸组成的药物活性化合物，具有2至5个氨基酸的肽或肽衍生物，其与这些共价键合，以及这些组合物的药学上可接受的盐或溶剂合物作为 以及这些物质用于生产药物组合物的用途，特别是用于治疗血小板聚集和肿瘤治疗。 因此，本发明的应用领域是医药和制药工业。 根据本发明的化合物具有通式（I）。 X-Pep（I），其中X是异黄酮或异黄酮糖苷，Pep是具有2至5个氨基酸的氨基酸或肽或肽衍生物，X和Pep之间具有共价键或 连接器系统。