专利检索 ap:("MARK B. ANDERSON" OR "J. Adam Willardsen" OR "Warren S. Weiner" OR "Kazuyuki Suzuki" OR "Robert J. Halter" OR "In Chul Kim" OR "Matthew Reeder" OR "Ashantai Yungai") AND inv:"Matthew Reeder" 第 1 页

1.

发明申请
PHARMACEUTICAL COMPOUNDS AS INHIBITORS OF CELL PROLIFERATION AND THE USE THEREOF 审中-公开
标题翻译：作为细胞增殖抑制剂的药物化合物及其用途

公开(公告)号：US20100068197A1

公开(公告)日：2010-03-18

申请号：US12500449

申请日：2009-07-09

申请人： MARK B. ANDERSON , J. Adam Willardsen , Warren S. Weiner , Kazuyuki Suzuki , Robert J. Halter , In Chul Kim , Matthew Reeder , Ashantai Yungai

发明人： MARK B. ANDERSON , J. Adam Willardsen , Warren S. Weiner , Kazuyuki Suzuki , Robert J. Halter , In Chul Kim , Matthew Reeder , Ashantai Yungai

IPC分类号： A61K31/517 , C07D239/95 , C07D403/12 , C07D487/04 , A61K31/5025 , A61P35/00 , A61K39/395 , C12N5/00

CPC分类号： C07D403/12 , C07D239/95 , C07D487/04

摘要： Disclosed are compounds of Formula I effective as cytotoxic agents. The compounds of this invention are useful in the treatment of a variety of clinical conditions in which uncontrolled growth and spread of abnormal cells occurs.

摘要翻译： 公开了作为细胞毒性剂有效的式I化合物。本发明的化合物可用于治疗异常细胞发生不受控制的生长和扩散的各种临床病症。

2.

发明授权
Compounds and therapeutical use thereof 有权
标题翻译：化合物及其治疗用途

公开(公告)号：US08309562B2

公开(公告)日：2012-11-13

申请号：US12500863

申请日：2009-07-10

申请人： Mark B. Anderson , J. Adam Willardsen , Warren S. Weiner , Ashantai Yungai , Robert J. Halter , Yevgeniya Klimova , Kazuyuki Suzuki , Matthew Reeder

发明人： Mark B. Anderson , J. Adam Willardsen , Warren S. Weiner , Ashantai Yungai , Robert J. Halter , Yevgeniya Klimova , Kazuyuki Suzuki , Matthew Reeder

IPC分类号： A01N43/54 , A61K31/517 , C07D239/72

CPC分类号： C07D239/94 , C07D239/95 , C07D401/12 , C07D403/04 , C07D403/12 , C07D405/12 , C07D487/04

摘要： Disclosed are 4-arylamino-quinazolines and analogs thereof that are effective as activators of caspases and inducers of apoptosis. The compounds of this invention are useful in the treatment of a variety of clinical conditions in which uncontrolled growth and spread of abnormal cells occurs.

摘要翻译： 公开了作为胱天蛋白酶的活化剂和凋亡诱导剂的4-芳基氨基 - 喹唑啉及其类似物。本发明的化合物可用于治疗异常细胞发生不受控制的生长和扩散的各种临床病症。

3.

发明申请
COMPOUNDS AND THERAPEUTICAL USE THEREOF 有权
标题翻译：化合物及其治疗用途

公开(公告)号：US20100069383A1

公开(公告)日：2010-03-18

申请号：US12500863

申请日：2009-07-10

申请人： MARK B. ANDERSON , J. Adam Willardsen , Warren S. Weiner , Ashantai Yungai , Robert J. Halter , Yevgeniya Klimova , Kazuyuki Suzuki , Matthew Reeder

发明人： MARK B. ANDERSON , J. Adam Willardsen , Warren S. Weiner , Ashantai Yungai , Robert J. Halter , Yevgeniya Klimova , Kazuyuki Suzuki , Matthew Reeder

IPC分类号： A61K31/517 , A61K31/5377 , A61K31/52 , C07D413/12 , C07D473/00 , C07D401/12 , C07D239/95

CPC分类号： C07D239/94 , C07D239/95 , C07D401/12 , C07D403/04 , C07D403/12 , C07D405/12 , C07D487/04

摘要： Disclosed are 4-arylamino-quinazolines and analogs thereof that are effective as activators of caspases and inducers of apoptosis. The compounds of this invention are useful in the treatment of a variety of clinical conditions in which uncontrolled growth and spread of abnormal cells occurs.

摘要翻译： 公开了作为胱天蛋白酶的活化剂和凋亡诱导剂的4-芳基氨基 - 喹唑啉及其类似物。本发明的化合物可用于治疗异常细胞发生不受控制的生长和扩散的各种临床病症。