公开(公告)号：US20230271142A1

公开(公告)日：2023-08-31

申请号：US18018078

申请日：2021-07-29

申请人： MICROPORE TECHNOLOGIES LIMITED

发明人： Elina Beveniou ,  Matt Bennett ,  Alex Kerr ,  Sam Trotter ,  David Hayward

IPC分类号： B01D69/02 ,  A61K31/40 ,  A61K31/4184 ,  B01D67/00 ,  B01D69/04 ,  B01D71/02 ,  B01D9/00 ,  B01F23/451

CPC分类号： B01D69/02 ,  A61K31/40 ,  A61K31/4184 ,  B01D67/0055 ,  B01D69/04 ,  B01D71/022 ,  B01D9/0013 ,  B01D9/0054 ,  B01D9/0063 ,  B01F23/451 ,  B01D2325/021

摘要： There is described a method of preparing solid particles of a compound, said method comprising controlling provision of a liquid phase, wherein said liquid phase comprises a solution of the compound, in a first flow direction to a membrane, said membrane defining a plurality of pores; and controlling the supersaturation of the liquid phase after it has passed through the membrane via the plurality of pores, to form solid particles of the compound. The method may comprise a continuous method.

公开(公告)号：US20230255894A1

公开(公告)日：2023-08-17

申请号：US18016143

申请日：2021-07-21

申请人： MICROPORE TECHNOLOGIES LIMITED

发明人： Alex Kerr ,  Sam Trotter ,  David Hayward

IPC分类号： A61K9/51 ,  A61K9/127 ,  A61K31/661 ,  B01D69/04

CPC分类号： A61K9/5192 ,  A61K9/1277 ,  A61K9/1271 ,  A61K31/661 ,  B01D69/04 ,  B01D2325/02

摘要： There is described a method of preparing lipid vesicles, said method comprising dispersing a first liquid phase in a second liquid phase; wherein said first liquid phase comprises a lipid phase and said second liquid phase comprises an aqueous phase; or said first liquid phase comprises an aqueous phase and said second liquid phase comprises a lipid phase; said method comprising controlling provision of the first liquid phase in a first flow direction to a membrane, said membrane defining a plurality of pores; and controlling provision of the second liquid phase to the membrane in a crossflow to the first flow direction, via the plurality of pores, to form a lipid vesicle suspension.