公开(公告)号：US20230255894A1

公开(公告)日：2023-08-17

申请号：US18016143

申请日：2021-07-21

申请人： MICROPORE TECHNOLOGIES LIMITED

发明人： Alex Kerr ,  Sam Trotter ,  David Hayward

IPC分类号： A61K9/51 ,  A61K9/127 ,  A61K31/661 ,  B01D69/04

CPC分类号： A61K9/5192 ,  A61K9/1277 ,  A61K9/1271 ,  A61K31/661 ,  B01D69/04 ,  B01D2325/02

摘要： There is described a method of preparing lipid vesicles, said method comprising dispersing a first liquid phase in a second liquid phase; wherein said first liquid phase comprises a lipid phase and said second liquid phase comprises an aqueous phase; or said first liquid phase comprises an aqueous phase and said second liquid phase comprises a lipid phase; said method comprising controlling provision of the first liquid phase in a first flow direction to a membrane, said membrane defining a plurality of pores; and controlling provision of the second liquid phase to the membrane in a crossflow to the first flow direction, via the plurality of pores, to form a lipid vesicle suspension.

公开(公告)号：US20230271142A1

公开(公告)日：2023-08-31

申请号：US18018078

申请日：2021-07-29

申请人： MICROPORE TECHNOLOGIES LIMITED

发明人： Elina Beveniou ,  Matt Bennett ,  Alex Kerr ,  Sam Trotter ,  David Hayward

IPC分类号： B01D69/02 ,  A61K31/40 ,  A61K31/4184 ,  B01D67/00 ,  B01D69/04 ,  B01D71/02 ,  B01D9/00 ,  B01F23/451

CPC分类号： B01D69/02 ,  A61K31/40 ,  A61K31/4184 ,  B01D67/0055 ,  B01D69/04 ,  B01D71/022 ,  B01D9/0013 ,  B01D9/0054 ,  B01D9/0063 ,  B01F23/451 ,  B01D2325/021

摘要： There is described a method of preparing solid particles of a compound, said method comprising controlling provision of a liquid phase, wherein said liquid phase comprises a solution of the compound, in a first flow direction to a membrane, said membrane defining a plurality of pores; and controlling the supersaturation of the liquid phase after it has passed through the membrane via the plurality of pores, to form solid particles of the compound. The method may comprise a continuous method.

公开(公告)号：US20230285913A1

公开(公告)日：2023-09-14

申请号：US17927497

申请日：2021-05-28

申请人： MICROPORE TECHNOLOGIES LIMITED

发明人： Sam Trotter ,  Bruce Williams

IPC分类号： B01F23/41 ,  B01F25/314 ,  B01F25/433 ,  B01F25/442 ,  B01F25/441

CPC分类号： B01F23/413 ,  B01F23/4105 ,  B01F25/31421 ,  B01F25/3141 ,  B01F25/4334 ,  B01F25/4422 ,  B01F25/4413

摘要： Membrane Emulsification Apparatus with Refiner There is described a membrane emulsification apparatus for dispersing a first phase in a second phase, comprising: •a membrane defining a plurality of apertures connecting a first volume on a first side of the membrane to a second volume on a second, different, side of the membrane, the apparatus being arranged to receive a first phase containing a liquid in the first volume and to receive a second phase in the second volume the apparatus being adapted to generate an emulsion through egression of the first phase into the second phase via the plurality of apertures; •the apparatus also comprising a refiner (1) arranged to receive the emulsion from the membrane; and wherein said refiner comprises an inlet (4/5) and an outlet (5/4) wherein an opening (8) adapted to converge flow of the emulsion and to break up droplets of the emulsion into a refined emulsion is located between the inlet and the outlet.