专利检索 ap:("MSN LABORATORIES PRIVATE LIMITED, R&D CENTER") AND inv:"Venkata Panakala Rao Gogulapati" 第 1 页

1.

发明授权
Polymorphs of 4-[3-chloro-4-(n′-cyclopropyl ureido)phenoxy] -7-methoxyquinoline-6-carboxamide, its salts and process for the preparation thereof 有权

公开(公告)号：US11236050B2

公开(公告)日：2022-02-01

申请号：US16771096

申请日：2018-12-08

申请人： MSN LABORATORIES PRIVATE LIMITED, R&D CENTER , Thirumalai Rajan Srinivasan

发明人： Thirumalai Rajan Srinivasan , Eswaraiah Sajja , Venkata Panakala Rao Gogulapati , Rajeshwar Reddy Sagyam , Pavan Kumar Reddy Bandla , Srinivasulu Rangineni

IPC分类号： C07D215/18 , C07D215/48

摘要： The present invention relates to novel polymorphs of 4-[3-chloro-4-(N′-cyclopropyl ureido) phenoxy]-7-methoxyquinoline-6-carboxamide methanesulfonate represented by following structural formula-1a and process for preparation thereof. Further, the present invention relates to an improved process for the preparation of 4-[3-chloro-4-(N′-cyclopropylureido) phenoxy]-7-methoxyquinoline-6-carboxamide compound of formula-1 or its salts and its intermediates thereof.

2.

发明授权
Process for the preparation of 3α,7α-dihydroxy-6α-ethyl-5β-cholan-24-oic acid 有权

公开(公告)号：US11434256B2

公开(公告)日：2022-09-06

申请号：US16965243

申请日：2019-01-25

申请人： MSN LABORATORIES PRIVATE LIMITED, R&D CENTER

发明人： Thirumalai Rajan Srinivasan , Eswaraiah Sajja , Venkata Panakala Rao Gogulapati , Ganapathi Chary Nagunuri

IPC分类号： C07J9/00

摘要： The present invention relates to an improved process for the preparation of 3α,7α-dihydroxy6α-ethyl-5β-cholan-24-oic acid compound of formula-1, represented by the following structural formula: Formula-1 The present invention also relates to process for the preparation of ethylene diamine and tertiary butyl amine salts of 3α,7α-dihydroxy6α-ethyl-5β-cholan-24-oic acid which are useful in the preparation of pure 3α,7α-dihydroxy6α-ethyl-5β-cholan-24-oic acid.

3.

发明授权
Process for the preparation of N-(4-(6,7-dimethoxyquinolin-4-yloxy)phenyl)-N′-(4-fluorophenyl)cyclopropane-1, 1-dicarboxamide, (2S)-hydroxybutanedioate and its polymorphs thereof 有权

公开(公告)号：US11261160B2

公开(公告)日：2022-03-01

申请号：US16467853

申请日：2017-12-06

申请人： MSN LABORATORIES PRIVATE LIMITED, R&D CENTER , Thirumalai Rajan Srinivasan , Eswaraiah Sajja , Venkata Panakala Rao Gogulapati , Rajeshwar Reddy Sagyam , Shyam Kiran Babu Gandham , Rajesham Boge

发明人： Thirumalai Rajan Srinivasan , Eswaraiah Sajja , Venkata Panakala Rao Gogulapati , Rajeshwar Reddy Sagyam , Shyam Kiran Babu Gandham , Rajesham Boge

IPC分类号： C07D215/233

摘要： The present invention also relates to process for the preparation of N-(4-(6,7-dimethoxy quinolin-4-yloxy)phenyl)-N′-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide (S)-malate compound of formula-1a and its polymorphs thereof, represented by the following structural: