公开(公告)号：US09478026B2

公开(公告)日：2016-10-25

申请号：US14673991

申请日：2015-03-31

Applicant: MUSC Foundation for Research Development ,  Golbarg Tarighat Saber

Inventor： Jens Jensen ,  Ali Tabesh ,  Joseph Helpern

IPC: G06T7/00 ,  A61B5/00 ,  A61B5/16 ,  A61B5/055 ,  G01R33/563

CPC classification number: G06T7/0012 ,  A61B5/0042 ,  A61B5/055 ,  A61B5/168 ,  A61B5/4088 ,  A61B5/4094 ,  A61B2576/026 ,  G01R33/56341 ,  G06T7/11 ,  G06T2207/10092 ,  G06T2207/30016

Abstract: One aspect of the present disclosure relates to a system that can determine a kurtosis diffusion orientation distribution function (dODF) that can, for example, be used with diffusional kurtosis imaging fiber tractography (DKI-FT). The system can include a non-transitory memory storing computer-executable instructions and a processor that executes the computer-executable instructions to perform the following operations. Diffusion magnetic resonance imaging (dMRI) data can be received. Based on the dMRI data, a diffusion tensor (DT) and a diffusional kurtosis tensor (DKT) can be determined. A kurtosis dODF can be determined for the dMRI data based on the DT and the DKT. The kurtosis dODF extends a Gaussian approximation of the DT to include non-Gaussian corrections of the DKT.

Abstract translation: 本公开的一个方面涉及一种可以确定峰值扩散取向分布函数（dODF）的系统，其可以例如与扩散峭度成像纤维束图（DKI-FT）一起使用。 该系统可以包括存储计算机可执行指令的非暂存存储器和执行计算机可执行指令以执行以下操作的处理器。 可以接收扩散磁共振成像（dMRI）数据。 基于dMRI数据，可以确定扩散张量（DT）和弥散张度张量（DKT）。 可以基于DT和DKT来确定dMRI数据的峰度dODF。 峰度dODF扩展了DT的高斯近似，以包括DKT的非高斯校正。

公开(公告)号：US20150279029A1

公开(公告)日：2015-10-01

申请号：US14673991

申请日：2015-03-31

Applicant: MUSC Foundation for Research Development

Inventor： Jens Jensen ,  Ali Tabesh ,  Joseph Helpern

IPC: G06T7/00 ,  A61B5/00 ,  A61B5/16 ,  A61B5/055

CPC classification number: G06T7/0012 ,  A61B5/0042 ,  A61B5/055 ,  A61B5/168 ,  A61B5/4088 ,  A61B5/4094 ,  A61B2576/026 ,  G01R33/56341 ,  G06T7/11 ,  G06T2207/10092 ,  G06T2207/30016

Abstract: One aspect of the present disclosure relates to a system that can determine a kurtosis diffusion orientation distribution function (dODF) that can, for example, be used with diffusional kurtosis imaging fiber tractography (DKI-FT). The system can include a non-transitory memory storing computer-executable instructions and a processor that executes the computer-executable instructions to perform the following operations. Diffusion magnetic resonance imaging (dMRI) data can be received. Based on the dMRI data, a diffusion tensor (DT) and a diffusional kurtosis tensor (DKT) can be determined. A kurtosis dODF can be determined for the dMRI data based on the DT and the DKT. The kurtosis dODF extends a Gaussian approximation of the DT to include non-Gaussian corrections of the DKT.

Abstract translation: 本公开的一个方面涉及一种可以确定峰值扩散取向分布函数（dODF）的系统，其可以例如与扩散峭度成像纤维束图（DKI-FT）一起使用。 该系统可以包括存储计算机可执行指令的非暂存存储器和执行计算机可执行指令以执行以下操作的处理器。 可以接收扩散磁共振成像（dMRI）数据。 基于dMRI数据，可以确定扩散张量（DT）和弥散张度张量（DKT）。 可以基于DT和DKT来确定dMRI数据的峰度dODF。 峰度dODF扩展了DT的高斯近似，以包括DKT的非高斯校正。

公开(公告)号：US09940708B2

公开(公告)日：2018-04-10

申请号：US14618345

申请日：2015-02-10

Applicant: MUSC Foundation for Research Development

Inventor： Jens Jensen ,  Sai Kam Hui ,  Joseph Helpern

IPC: G01V3/00 ,  G06T7/00 ,  G01R33/563

CPC classification number: G06T7/0012 ,  G01R33/56341 ,  G06T2207/10088 ,  G06T2207/20076 ,  G06T2207/30016

Abstract: One aspect of the present disclosure relates to a system that can perform double pulsed diffusional kurtosis imaging (DP-DKI). Image data can be received. The image data can be acquired using a double pulsed field gradient (d-PFG) diffusion sequence. A six dimensional (6D) diffusional kurtosis for the image data can be determined. A magnitude of the image data can be determined in terms of the 6D diffusional kurtosis. DP-DKI can isolate the contributions to the d-PFG diffusion sequence, which can represent leading diffusion effects, that cannot be seen from single pulsed field gradient (s-PFG) diffusion sequences.

公开(公告)号：US20150228073A1

公开(公告)日：2015-08-13

申请号：US14618345

申请日：2015-02-10

Applicant: MUSC Foundation for Research Development

Inventor： Jens Jensen ,  Sai Kam Hui ,  Joseph Helpern

IPC: G06T7/00

CPC classification number: G06T7/0012 ,  G01R33/56341 ,  G06T2207/10088 ,  G06T2207/20076 ,  G06T2207/30016

Abstract: One aspect of the present disclosure relates to a system that can perform double pulsed diffusional kurtosis imaging (DP-DKI). Image data can be received. The image data can be acquired using a double pulsed field gradient (d-PFG) diffusion sequence. A six dimensional (6D) diffusional kurtosis for the image data can be determined. A magnitude of the image data can be determined in terms of the 6D diffusional kurtosis. DP-DKI can isolate the contributions to the d-PFG diffusion sequence, which can represent leading diffusion effects, that cannot be seen from single pulsed field gradient (s-PFG) diffusion sequences.

Abstract translation: 本公开的一个方面涉及可执行双脉冲扩散峭度成像（DP-DKI）的系统。 可以接收图像数据。 可以使用双脉冲场梯度（d-PFG）扩散序列来获取图像数据。 可以确定图像数据的六维（6D）扩散峰度。 可以根据6D扩散峰度来确定图像数据的大小。 DP-DKI可以分离对d-PFG扩散序列的贡献，这可以代表主要的扩散效应，从单脉冲场梯度（s-PFG）扩散序列看不到。