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公开(公告)号：US4621075A
公开(公告)日：1986-11-04
申请号：US676027
申请日：1984-11-28
申请人： Mahdi B. Fawzi , Gary L. Manring
发明人： Mahdi B. Fawzi , Gary L. Manring
IPC分类号： A61K33/30 , A61K20060101 , A61K9/06 , A61K9/10 , A61K31/315 , A61K31/70 , A61K31/7028 , A61K47/00 , A61P31/04 , C07H15/16
摘要： Topical pharmaceutical compositions, containing clindamycin phosphate, a zinc fatty acid salt, such as zinc acetate, and a non-aqueous vehicle, are disclosed. The compositions provide antibiotic performance and are present as physically stable, aesthetically-pleasing, clear, ringing gels, without requiring the use of conventional gelling agents. The method of topically treating clindamycin responsive dermatoses, such as acne, using these compositions is also disclosed.
摘要翻译： 公开了含有克林霉素磷酸盐，脂肪酸锌盐如乙酸锌和非水性载体的局部药物组合物。 所述组合物提供抗生素性能，并且作为物理稳定的，美观的，清澈的，凝胶状凝胶存在，而不需要使用常规的胶凝剂。 还公开了使用这些组合物局部治疗克林霉素敏感性皮肤病如粉刺的方法。
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公开(公告)号：US20090137559A1
公开(公告)日：2009-05-28
申请号：US12363906
申请日：2009-02-02
申请人： Mahdi B. Fawzi , Kadum A. Ali , Syed M. Shah
发明人： Mahdi B. Fawzi , Kadum A. Ali , Syed M. Shah
IPC分类号： A61K31/55 , C07D403/12 , A61P35/00
CPC分类号： C07D209/12
摘要： The present invention is directed to bazedoxifene ascorbate, compositions containing the same, dispersions thereof, preparations thereof, and uses thereof.
摘要翻译： 本发明涉及抗坏血酸巴西多昔芬，含有它们的组合物，其分散体，制剂及其用途。
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公开(公告)号：US06677357B2
公开(公告)日：2004-01-13
申请号：US10224971
申请日：2002-08-22
申请人： Tianmin Zhu , Mahdi B. Fawzi
发明人： Tianmin Zhu , Mahdi B. Fawzi
IPC分类号： A61K31445
CPC分类号： C07D405/06 , C07D493/08
摘要： This invention provides non-immunosuppressive rapamycin 29-enols, which are useful as neurotrophic agents, in the treatment of solid tumors, and vascular disease.
摘要翻译： 本发明提供了用于治疗实体瘤和血管疾病的非免疫抑制雷帕霉素29-烯醇，其可用作神经营养剂。
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公开(公告)号：US4931519A
公开(公告)日：1990-06-05
申请号：US347630
申请日：1989-05-05
CPC分类号： C08F26/06 , A61K9/284 , A61K9/2846 , A61K9/7023 , A61L15/24 , C07D207/38 , G02B1/043
摘要： A new series of copolymers which are useful as coatings for solid dosage forms, for transdermal devices, for wound dressing materials, and for contact lenses. Also disclosed are methods for preparing monomers and polymers as well as pharmaceutical compositions containing such polymers.
摘要翻译： 可用作固体剂型涂层，透皮装置，伤口敷料材料和隐形眼镜的新系列共聚物。 还公开了制备单体和聚合物的方法以及含有这种聚合物的药物组合物。
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公开(公告)号：US4925676A
公开(公告)日：1990-05-15
申请号：US305083
申请日：1989-02-02
申请人： Isaac Ghebre-Sellassie , Uma Iyer , Mahdi B. Fawzi
发明人： Isaac Ghebre-Sellassie , Uma Iyer , Mahdi B. Fawzi
CPC分类号： A61K31/19 , A61K9/2081
摘要： A disintegratable gemfibrozil tablet providing both immediate and enteric release is compressed from a mixture of a first granulation of gemfibrozil with at least one acid-disintegratable binder and a second granulation formed from the first granulation but regranulated or coated with an alkali-disintegratable formulation of at least one substantially alkali-soluble and substantially acid-insoluble polymer.
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公开(公告)号：USD302481S
公开(公告)日：1989-07-25
申请号：US111525
申请日：1987-10-21
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公开(公告)号：US4830853A
公开(公告)日：1989-05-16
申请号：US921717
申请日：1986-10-20
申请人： Kuchi S. Murthy , Michael R. Harris , Gerard C. Hokanson , Robert G. Reisch, Jr. , Mahdi B. Fawzi , Frank Waldman
发明人： Kuchi S. Murthy , Michael R. Harris , Gerard C. Hokanson , Robert G. Reisch, Jr. , Mahdi B. Fawzi , Frank Waldman
IPC分类号： A61K45/08 , A61K31/40 , A61K31/401 , A61K31/44 , A61K31/47 , A61K47/00 , A61K47/12 , A61K47/22 , A61P9/12 , A61P43/00
摘要： The oxidation--and color-stability of certain ace inhibitors is optimized when they are formulated with a stabilizer and at least one lubricant and/or excipient.
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公开(公告)号：US4783450A
公开(公告)日：1988-11-08
申请号：US037671
申请日：1987-04-13
申请人： Mahdi B. Fawzi , Uma R. Iyer , Majid Mahjour
发明人： Mahdi B. Fawzi , Uma R. Iyer , Majid Mahjour
IPC分类号： A61K31/135 , A61K31/47 , A61K31/485 , A61K31/685 , A61K36/48 , A61K45/08 , A61K47/24 , A61P11/08 , A61P11/14 , A61P25/04 , A61P43/00
CPC分类号： A61K47/24 , A61K9/0014 , Y10S514/946 , Y10S514/969
摘要： A method of enhancing penetration of a drug through the skin or other biological membranes using lecithin is herein described along with pharmaceutical compositions containing effective amounts of lecithin as a penetration enhancer.
摘要翻译： 此外，与含有有效量的卵磷脂作为渗透促进剂的药物组合物一起描述了使用卵磷脂增强药物穿过皮肤或其他生物膜的渗透的方法。
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公开(公告)号：US4343798A
公开(公告)日：1982-08-10
申请号：US276556
申请日：1981-06-23
申请人： Mahdi B. Fawzi
发明人： Mahdi B. Fawzi
CPC分类号： A61K31/57 , Y10S514/887
摘要： Topical antimicrobial anti-inflammatory compositions, having a pH no greater than about 5, containing C.sub.5 -C.sub.12 fatty acids together with a corticosteroid component, are disclosed. The method of topically treating inflammatory skin conditions using these compositions is also disclosed.
摘要翻译： 公开了具有包含C 5 -C 12脂肪酸和皮质类固醇成分的pH不大于约5的局部抗微生物抗炎组合物。 还公开了使用这些组合物局部治疗炎性皮肤病症的方法。
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10.发明授权公开(公告)号：US08133883B2
公开(公告)日：2012-03-13
申请号：US13033861
申请日：2011-02-24
CPC分类号： A61K9/0019 , A61K31/43 , A61K31/431 , A61K31/496 , A61K47/183 , A61K2300/00
摘要： An aminocarboxylic acid chelating agent, preferably EDTA, or a salt thereof has been found to be useful for inhibiting particulate formation in piperacillin/tazobactam parenteral combinations. The composition may also contain a buffer, preferably citrate, and optionally an aminoglycoside. The product may be in the form of a frozen composition that can be thawed for use. The product may also be in the form of a cryodesiccated powder that can be reconstituted by addition of an aqueous vehicle to reform a solution.
摘要翻译： 已经发现氨基羧酸螯合剂，优选EDTA或其盐可用于抑制哌拉西林/他唑巴坦肠胃外组合中的颗粒形成。 组合物还可以含有缓冲液，优选柠檬酸盐，和任选的氨基糖苷类。 产品可以是可以解冻使用的冷冻组合物的形式。 该产品还可以是可以通过加入水性载体来重构溶液的冷冻消毒粉末的形式。
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