AGENT FOR ENHANCING THE PRODUCTION OF CYTOKINES AND/OR CHEMOKINES
    1.
    发明申请
    AGENT FOR ENHANCING THE PRODUCTION OF CYTOKINES AND/OR CHEMOKINES 审中-公开
    用于增强细胞因子和/或细胞因子生产的代理

    公开(公告)号:US20090148943A1

    公开(公告)日:2009-06-11

    申请号:US12265348

    申请日:2008-11-05

    IPC分类号: C12N5/06

    CPC分类号: C07K14/4705 A61K38/00

    摘要: The present invention has an object to provide a means to effectively enhance the production of cytokines and/or chemokines in mammals. The object is solved by providing an agent for enhancing the production of cytokines and/or chemokines, which comprises, as an effective ingredient, a polypeptide having any one of the amino acid sequences of SEQ ID NOs:1 to 3; a polypeptide having any one of the amino acid sequences of SEQ ID NOs:1 to 3, where one or more amino acids thereof are deleted or replaced with other amino acid(s) and/or one or more amino acids are added thereunto, without substantially losing the biological activity of the polypeptide.

    摘要翻译: 本发明的目的是提供有效增强哺乳动物中细胞因子和/或趋化因子的产生的方法。 通过提供用于增强细胞因子和/或趋化因子的产生的试剂来解决该问题,所述试剂包含作为有效成分的具有SEQ ID NO:1至3的任一氨基酸序列的多肽; 具有SEQ ID NO:1至3的任何一个氨基酸序列的多肽,其中一个或多个氨基酸被缺失或被其它氨基酸和/或一个或多个氨基酸所取代,而没有 基本上丧失了多肽的生物活性。

    HEAT ENGINE
    2.
    发明申请
    HEAT ENGINE 有权
    热发动机

    公开(公告)号:US20110252780A1

    公开(公告)日:2011-10-20

    申请号:US12821859

    申请日:2010-06-23

    申请人: Makoto TAKEUCHI

    发明人: Makoto TAKEUCHI

    IPC分类号: F02G1/044 F01B29/10

    CPC分类号: F02G1/044 F02G2243/06

    摘要: A heat engine includes: a high-temperature space portion and a low-temperature space portion, each of which has a working gas with a different temperature range from each other; a regenerator provided between both of the space portions; a first piston configured to cause volumetric changes of the working gases in the space portions and transmit motive energy on receipt of pressure changes of the working gases; and a second piston and a third piston provided in the space portions, respectively, the second piston and the third piston configured to transfer the working gases between both of the space portions and move with a 180° phase difference from each other with respect to the regenerator. The second piston is slidably housed in a cylinder portion included in the first piston. The first piston, and the second piston and the third piston are configured to move with a phase difference smaller than 180°. Heat and motive energy are exchanged by using the volumetric changes in both of the space portions, as well as by using the transfer of the working gases.

    摘要翻译: 热机包括:高温空间部分和低温空间部分,每个部分具有彼此具有不同温度范围的工作气体; 设置在两个空间部分之间的再生器; 第一活塞构造成在空间部分中引起工作气体的体积变化,并在接收到工作气体的压力变化时传递动能; 以及分别设置在所述空间部分中的第二活塞和第三活塞,所述第二活塞和所述第三活塞被构造成在两个空间部分之间传递工作气体,并相对于所述空间部分以180°的相位差移动 再生器。 第二活塞可滑动地容纳在包括在第一活塞中的气缸部分中。 第一活塞,第二活塞和第三活塞构造成以小于180°的相位差移动。 通过使用两个空间部分中的体积变化以及通过使用工作气体的转移来交换热量和动能。

    BEARING STRUCTURE USING RESIN BUSH
    4.
    发明申请
    BEARING STRUCTURE USING RESIN BUSH 有权
    轴承结构使用树脂布

    公开(公告)号:US20110156464A1

    公开(公告)日:2011-06-30

    申请号:US12978835

    申请日:2010-12-27

    IPC分类号: A47C7/54 F16C33/74

    摘要: According to a first aspect of the invention, there is provided a bearing structure including: a resin bush having a flange formed to be brought into contact with a plate face around a bearing hole from one side, a locking edge formed to be locked with the plate face around the bearing hole from the other side, and a circular through-hole formed to bear the support shaft inserted therethrough, wherein, upon receiving a load applied to the support shaft, the entire resin bush is flexibly displaced so that an inner circumferential surface of the through-hole is aligned with a hole edge of the bearing hole and the support shaft is born by the hole edge of the bearing hole.

    摘要翻译: 根据本发明的第一方面,提供了一种轴承结构,其包括:树脂衬套,其具有形成为与来自一侧的轴承孔周围的板面接触的凸缘,形成为与所述轴承孔锁定的锁定边缘 板形面从另一侧围绕轴承孔,形成为承载插入其中的支撑轴的圆形通孔,其中,在接收到施加到支撑轴上的负载时,整个树脂衬套被灵活地移位,使得内周 通孔的表面与轴承孔的孔边缘对齐,支撑轴由轴承孔的孔边缘承受。

    Exhaust Passage Component
    5.
    发明申请
    Exhaust Passage Component 有权
    排气组件

    公开(公告)号:US20120138163A1

    公开(公告)日:2012-06-07

    申请号:US13311748

    申请日:2011-12-06

    IPC分类号: B67D7/72

    摘要: An exhaust passage component includes: an inner space used as part of an exhaust passage of a hot water supply apparatus; a drainage passage configured such that if condensed water is produced in the inner space, the condensed water is caused to flow out of the inner space; a first sheet metal member, at least part of which includes a first recess formed by drawing and a plate-like portion formed around the first recess; and a second sheet metal member, at least part of which includes a second recess by drawing and a flange formed around the second recess.

    摘要翻译: 排气通道部件包括:用作热水供应装置的排气通道的一部分的内部空间; 排水通道,其构造成如果在内部空间中产生冷凝水,则使冷凝水从内部空间流出; 第一钣金构件,其至少一部分包括通过拉伸形成的第一凹部和形成在第一凹部周围的板状部分; 以及第二钣金构件,其至少一部分包括通过拉伸的第二凹部和围绕第二凹部形成的凸缘。

    LASER WELDING METHOD AND PIPE JOINT PRODUCT JOINED BY THE METHOD
    6.
    发明申请
    LASER WELDING METHOD AND PIPE JOINT PRODUCT JOINED BY THE METHOD 审中-公开
    激光焊接方法和管接头产品加入方法

    公开(公告)号:US20110284666A1

    公开(公告)日:2011-11-24

    申请号:US13112383

    申请日:2011-05-20

    IPC分类号: F02M63/00 B32B1/08 B23K26/00

    摘要: According to a laser welding method, an inert gas injection process and welding process are performed. In the inert gas injection process, inert gas is injected into an inside of a first metal pipe; and air inside the first pipe is discharged into the outside. In the welding process, a second metal pipe is irradiated with a laser from radially outward of the second pipe; metal is melted with a penetration depth of a penetration part adjusted such that a leading end of the penetration part is located within thickness of the first pipe; and the first and second pipes are welded together along the circumferential direction to form a pipe joint product. An inner wall of the first pipe maintains its pre-welding metallic luster. An injector includes an injection nozzle, a fuel passage member, a valve member accommodated in the fuel passage member, and a driving unit driving the valve member. The fuel passage member is welded as the first pipe by the laser welding method to maintain pre-welding metallic luster on an inner wall of the fuel passage member.

    摘要翻译: 根据激光焊接方法,进行惰性气体注入处理和焊接工序。 在惰性气体注入方法中,将惰性气体注入到第一金属管的内部; 第一管内的空气排出到外部。 在焊接过程中,第二金属管从第二管的径向外侧用激光照射; 金属熔化,其穿透深度被调整为使得穿透部分的前端位于第一管的厚度内; 并且第一和第二管沿圆周方向焊接在一起以形成管接头产品。 第一管的内壁保持其预焊金属光泽。 喷射器包括喷嘴,燃料通道构件,容纳在燃料通道构件中的阀构件以及驱动阀构件的驱动单元。 燃料通道构件通过激光焊接方法作为第一管焊接,以将预焊金属光泽保持在燃料通道构件的内壁上。