Apparatus for treating biomolecules
    1.
    发明授权
    Apparatus for treating biomolecules 有权
    用于治疗生物分子的装置

    公开(公告)号:US06177009B1

    公开(公告)日:2001-01-23

    申请号:US09262012

    申请日:1999-03-04

    IPC分类号: B01D1508

    摘要: Disclosed is an apparatus for isolating nucleic acids having a separation column which has a top inlet and a bottom outlet in which a separation device is arranged, and having a collection vessel for collecting liquid emerging from the outlet. The ratio between the internal volume of the separation column above the separation device and the surface area of the separation device is at least 10 ml/cm2.

    摘要翻译: 公开了一种用于分离具有分离塔的核酸的装置,该分离塔具有顶部入口和底部出口,其中布置有分离装置,并且具有用于收集从出口出来的液体的收集容器。 分离装置之上的分离塔的内部容积与分离装置的表面积之间的比例至少为10ml / cm2。

    Method for purifying biological marcromolecules, and chromatographic column for performing said method
    2.
    发明授权
    Method for purifying biological marcromolecules, and chromatographic column for performing said method 有权
    纯化生物大分子的方法,以及用于进行所述方法的色谱柱

    公开(公告)号:US06428703B1

    公开(公告)日:2002-08-06

    申请号:US09471152

    申请日:1999-12-23

    IPC分类号: B01D1508

    摘要: The invention concerns a method for purifying biological macromolecules, e.g. nucleic acids or proteins, from starting materials, in which the macromolecules, contained in a biological solution, are purified on a chromatographic material, and in which endotoxins are partially or completely removed with the aid of a nonionic surfactant, which is characterized in that the surfactant and the biological solution are brought into contact immediately before or during the purification of the macromolecules on the chromatographic material.

    摘要翻译: 本发明涉及一种纯化生物大分子的方法, 来自原料的核酸或蛋白质,其中包含在生物溶液中的大分子在色谱材料上纯化,并且其中内毒素在非离子表面活性剂的帮助下部分或完全除去,其特征在于, 表面活性剂和生物溶液在色谱材料上的大分子纯化之前或期间接触。