Capping machine
    2.
    发明授权
    Capping machine 有权
    封盖机

    公开(公告)号:US08353145B2

    公开(公告)日:2013-01-15

    申请号:US12671142

    申请日:2008-08-01

    IPC分类号: B67B3/20 B67B3/22 B67B3/28

    CPC分类号: B67B3/10 B67B3/2033 B67B3/28

    摘要: A capping machine (1) of carousel design comprises a centre shaft (2) turning on a fixed base frame (3) about a vertical axis of rotation (Y), a set of capping units (4) encircling and revolving as one with the shaft (2) about the axis of rotation (Y), and a cylindrical cam (5) interposed between the shaft (2) and the capping units (4), by which the single units (4) are caused to move toward and away from the fixed base frame (3). During operation, the cam (5) is held in at least one predetermined fixed position relative to the base frame (3) by a single supporting element (6) anchored to the base frame (3), concealed internally of the rotating shaft (2) and connected to the cam (5), which represents a departure from the conventional method of supporting the cam on two or more columns located externally of the carousel structure and exposed to view.

    摘要翻译: 圆盘传送带设计的封盖机(1)包括围绕垂直旋转轴线(Y)转动固定基座框架(3)的中心轴(2),围绕旋转的一组封盖单元(4) 轴(2)围绕旋转轴线(Y),以及插入在轴(2)和封盖单元(4)之间的圆柱形凸轮(5),单个单元(4)通过该圆筒凸轮朝向和远离 从固定基架(3)。 在操作期间,凸轮(5)通过锚固到基架(3)的单个支撑元件(6)相对于基架(3)保持在至少一个预定的固定位置,隐藏在旋转轴(2)的内部 )并且连接到凸轮(5),这代表了偏离凸轮在传送带结构外部暴露在两个或更多个柱上的常规方法的偏离。

    Rotary conveyor
    3.
    发明授权
    Rotary conveyor 有权
    旋转输送机

    公开(公告)号:US07823717B2

    公开(公告)日:2010-11-02

    申请号:US12227287

    申请日:2007-05-17

    IPC分类号: B65G29/00

    摘要: A rotary conveyor (1) utilized in equipment (1a) for filling containers (2) with liquid or powder products includes a supporting shaft (8) aligned on a longitudinal axis (X) and coupled to relative drive components (10) associated with the shaft (8), by which the shaft is set in rotation about the axis (X). A support element (11) is keyed to the shaft (8), presenting a peripheral rim (12) with a plurality of slots (13) each designed to accommodate a container (2) transferred from a transport and/or processing device (3) forming part of the equipment (1a). The slots (13) incorporate restraining components (14) having grippers (15) movable between a position of engagement, in which the containers (2) are locked to the support element (11), and a position of disengagement in which no restraining force is applied to the containers (2).

    摘要翻译: 在用于用液体或粉末产品填充容器(2)的设备(1a)中使用的旋转式输送机(1)包括在纵向轴线(X)上对准的支撑轴(8),并连接到与 轴(8),轴绕轴线(X)旋转。 支撑元件(11)与轴(8)键合,呈现具有多个槽(13)的周边边缘(12),每个狭槽设计成容纳从运输和/或处理装置(3)传送的容器(2) )形成设备(1a)的一部分。 狭槽(13)包括具有夹持器(15)的限制部件(14),该夹具(15)能够在容器(2)锁定在支撑元件(11)的接合位置之间移动,并且其中没有约束力 被施加到容器(2)。

    Carousel for Processing Containers Filled With Liquid or Powder Products
    4.
    发明申请
    Carousel for Processing Containers Filled With Liquid or Powder Products 有权
    用于加工液体或粉末产品的容器的转盘

    公开(公告)号:US20100224283A1

    公开(公告)日:2010-09-09

    申请号:US12223193

    申请日:2007-02-12

    IPC分类号: B67C3/24 B65G29/00 B65B1/32

    CPC分类号: B67C3/22 B67C2003/2668

    摘要: Containers for packaging liquid or powder products are directed onto a carousel (1) presenting a support element (9) equipped with a number of peripheral stations (10), each accommodating a relative container (2), and set in rotation about a vertical axis (X) by a drive system (6) housed internally of floor-standing frame (5) on which the carousel (1) is mounted. The support element (9) presents substantially disc-like appearance and is hollow, composed of a top panel (11) and a bottom panel (12) distanced one from another in such a way as to create an annular chamber (13) between the two panels.

    摘要翻译: 用于将液体或粉末产品包装的容器被引导到转盘(1)上,所述转盘(1)具有配备有多个周边站(10)的支撑元件(9),每个周边站(10)容纳相对容器(2),并且围绕垂直轴 (6)安装在其上安装有转盘(1)的落地架(5)的内部。 支撑元件(9)呈现基本上圆盘状的外观并且是中空的,由顶板(11)和底板(12)组成,以便在彼此间隔开的方式上形成环形室(13) 两个面板。

    Rotary Conveyor
    5.
    发明申请
    Rotary Conveyor 有权
    旋转输送机

    公开(公告)号:US20090250314A1

    公开(公告)日:2009-10-08

    申请号:US12227287

    申请日:2007-05-17

    IPC分类号: B65G29/00

    摘要: A rotary conveyor (1) utilized in equipment (Ia) for filling containers (2) with liquid or powder products comprises a supporting shaft (8) aligned on a longitudinal axis (X) and coupled to relative drive components (10) associated with the shaft (8), by which the shaft is set in rotation about the axis (X), also a support element (11) keyed to the shaft (8), presenting a peripheral rim (12) with a plurality of slots (13) each designed to accommodate a container (2) transferred from a transport and/or processing device (3) forming part of the equipment (1a). The slots (13) incorporate restraining components (14) consisting in grippers (15) capable of movement between a position of engagement, in which the containers (2) are locked to the support element (11), and a position of disengagement in which no restraining force is applied to the containers (2).

    摘要翻译: 在用于用液体或粉末产品填充容器(2)的设备(1a)中使用的旋转输送机(1)包括在纵向轴线(X)上对准的支撑轴(8),并连接到与 轴(8),轴被围绕轴线(X)设置成旋转,还有一个与轴(8)相关联的支撑元件(11),呈现具有多个槽(13)的周边边缘(12) 每个设计用于容纳从构成设备(1a)的一部分的运输和/或处理装置(3)转移的容器(2)。 狭槽(13)包括限制部件(14),其包括能够在容器(2)锁定到支撑元件(11)的接合位置之间移动的夹具(15)和脱开位置 对容器(2)不施加约束力。

    Tetrahydropyridines, preparation method and pharmaceutical compositions containing same
    7.
    发明授权
    Tetrahydropyridines, preparation method and pharmaceutical compositions containing same 失效
    四氢吡啶类,制备方法和含有它们的药物组合物

    公开(公告)号:US06689797B2

    公开(公告)日:2004-02-10

    申请号:US10169528

    申请日:2002-10-15

    IPC分类号: A61K3144

    CPC分类号: C07D405/06 C07D409/06

    摘要: The present invention relates to compounds of formula (I): in which R1 represents a hydrogen or halogen atom, or a group CF3; R2 and R3 represent, independently, a hydrogen atom or a methyl group; n and n′ each represent, independently, 0 or 1; * represents the positions of attachment; A represents N or CH; X represents a sulfur or oxygen atom; R4 and R5 represent, independently, a hydrogen atom or a (C1-C6) alkyl group; and also their salts or solvates, to a method for the preparation thereof and to the pharmaceutical compositions containing them.

    摘要翻译: 本发明涉及式(I)化合物:其中R 1表示氢或卤素原子或基团CF 3; R 2和R 3独立地表示氢原子或甲基; n和n'各自独立地表示, 0或1; *表示连接位置; A表示N或CH; X表示硫或氧原子; R4和R5独立地表示氢原子或(C1-C6)烷基;以及它们的盐或 溶剂合物,其制备方法和含有它们的药物组合物。

    1-Phenylalkyl-1,2,3,6-tetrahydropyridines for treating Alzheimer's
disease
    9.
    发明授权
    1-Phenylalkyl-1,2,3,6-tetrahydropyridines for treating Alzheimer's disease 失效
    1-苯基烷基-1,2,3,6-四氢吡啶用于治疗阿尔茨海默病

    公开(公告)号:US6034090A

    公开(公告)日:2000-03-07

    申请号:US331006

    申请日:1999-07-27

    CPC分类号: C07D401/04 C07D211/70

    摘要: The invention relates to compounds of the formula in which: Y is --CH-- or --N--; R.sub.1 is hydrogen, a halogen or a CF.sub.3, (C.sub.1 -C.sub.4)alkyl or (C.sub.1 -C.sub.4)alkoxy group; R.sub.2 is a methyl or ethyl group; R.sub.3 and R.sub.4 are each hydrogen or a (C.sub.1 -C.sub.3)alkyl; and X is:(a) a (C.sub.1 -C.sub.6)alkyl, a (C.sub.1 -C.sub.6)alkoxy, a (C.sub.3 -C.sub.7)carboxyalkyl, a (C.sub.1 -C.sub.4)alkoxy-carbonyl(C.sub.1 -C.sub.6)alkyl, a (C.sub.3 -C.sub.7)carboxyalkoxy or a (C.sub.1 -C.sub.4)alkoxycarbonyl-(C.sub.1 -C.sub.6)alkoxy;(b) a radical selected from (C.sub.3 -C.sub.7)cycloalkyl, (C.sub.3 -C.sub.7)cycloalkoxy, (C.sub.3 -C.sub.7)-cycloalkylmethyl, (C.sub.3 -C.sub.7)cycloalkylamino and cyclohexenyl, it being possible for said radical to be substituted by a halogen, hydroxyl, (C.sub.1 -C.sub.4)-alkoxy, carboxyl, (C.sub.1 -C.sub.4)alkoxycarbonyl, amino or mono- or di-(C.sub.1 -C.sub.4)-alkylamino; or(c) a group selected from a phenyl, phenoxy, phenylamino, N-(C.sub.1 -C.sub.3)alkyl-phenylamino, phenylmethyl, phenylethyl, phenylcarbonyl, phenylthio, phenylsulfonyl, phenylsulfinyl and styryl, it being possible for said group to be monosubstituted or polysubstituted on the phenyl group by a halogen, CF.sub.3, (C.sub.1 -C.sub.4)alkyl, (C.sub.1 -C.sub.4)alkoxy, cyano, amino, mono- or di-(C.sub.1 -C.sub.4)alkyl-amino, (C.sub.1 -C.sub.4)acylamino, carboxyl, (C.sub.1 -C.sub.4)alkoxycarbonyl, aminocarbonyl, mono- or di-(C.sub.1 -C.sub.4)alkylaminocarbonyl, amino(C.sub.1 -C.sub.4)alkyl, hydroxy(C.sub.1 -C.sub.4)alkyl or halogeno(C.sub.1 -C.sub.4)alkyl;to a method of preparing them and to the pharmaceutical compositions containing them. These compounds have neurotrophic and neuroprotective activity.

    摘要翻译: PCT No.PCT / FR97 / 02286 Sec。 371日期:1999年7月27日 102(e)日期1997年7月27日PCT 1997年12月12日PCT PCT。 第WO98 / 25903号公报 日期:1998年6月18日本发明涉及下式的化合物,其中:Y为-CH-或-N-; R1是氢,卤素或CF3,(C1-C4)烷基或(C1-C4)烷氧基; R2是甲基或乙基; R3和R4各自为氢或(C1-C3)烷基; 并且X是:(a)(C 1 -C 6)烷基,(C 1 -C 6)烷氧基,(C 3 -C 7)羧基烷基,(C 1 -C 4)烷氧羰基(C 1 -C 6)烷基,(C 3 -C 7)羧基烷氧基或(C 1 -C 4)烷氧基羰基 - (C 1 -C 6)烷氧基; (c)选自(C 3 -C 7)环烷基,(C 3 -C 7)环烷氧基,(C 3 -C 7) - 环烷基甲基,(C 3 -C 7)环烷基氨基和环己烯基的基团,所述基团可以被卤素 ,羟基,(C 1 -C 4) - 烷氧基,羧基,(C 1 -C 4)烷氧基羰基,氨基或单 - 或二 - (C 1 -C 4) - 烷基氨基; 或(c)选自苯基,苯氧基,苯基氨基,N-(C1-C3)烷基 - 苯基氨基,苯基甲基,苯基乙基,苯基羰基,苯硫基,苯基磺酰基,苯基亚磺酰基和苯乙烯基的基团,所述基团可能是单取代的或 通过卤素,CF 3,(C 1 -C 4)烷基,(C 1 -C 4)烷氧基,氰基,氨基,单 - 或二 - (C 1 -C 4)烷基 - 氨基,(C 1 -C 4)酰基氨基, 羧基,(C 1 -C 4)烷氧基羰基,氨基羰基,单 - 或二 - (C 1 -C 4)烷基氨基羰基,氨基(C 1 -C 4)烷基,羟基(C 1 -C 4)烷基或卤代(C 1 -C 4) 涉及制备它们的方法和含有它们的药物组合物。 这些化合物具有神经营养和神经保护活性。